| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Ghost | - | - | - | $55,573,309 | 1,766 | $217,631,306 | Jul 13 | Paramount Pictures | false |
| 2 | Postcards from the Edge | - | - | - | $39,071,603 | 1,323 | $39,071,603 | Sep 14 | Columbia Pictures | false |
| 3 | Marked for Death | - | - | - | $34,932,759 | 1,974 | $46,044,396 | Oct 5 | Twentieth Century Fox | false |
| 4 | Goodfellas | - | - | - | $34,003,592 | 1,328 | $46,836,214 | Sep 19 | Warner Bros. | false |
| 5 | Pacific Heights | - | - | - | $25,283,729 | 1,291 | $29,381,956 | Sep 28 | Twentieth Century Fox | false |
| 6 | Flatliners | - | - | - | $23,056,008 | 1,483 | $61,489,265 | Aug 10 | Columbia Pictures | false |
| 7 | Presumed Innocent | - | - | - | $20,819,076 | 1,451 | $86,303,188 | Jul 27 | Warner Bros. | false |
| 8 | Fantasia 1990 Re-release | - | - | - | $18,395,740 | 481 | $25,363,371 | Oct 5 | Walt Disney Studios Motion Pictures | false |
| 9 | Darkman | - | - | - | $17,307,307 | 1,833 | $33,878,502 | Aug 24 | Universal Pictures | false |
| 10 | Death Warrant | - | - | - | $16,853,487 | 1,090 | $16,853,487 | Sep 14 | Metro-Goldwyn-Mayer (MGM) | false |
| 11 | Memphis Belle | - | - | - | $16,502,383 | 1,368 | $27,441,977 | Oct 12 | Warner Bros. | false |
| 12 | Narrow Margin | - | - | - | $10,873,237 | 1,253 | $10,873,237 | Sep 21 | TriStar Pictures | false |
| 13 | Problem Child | - | - | - | $10,850,295 | 1,769 | $53,470,891 | Jul 27 | Universal Pictures | false |
| 14 | Young Guns II | - | - | - | $10,630,826 | 1,770 | $44,143,410 | Aug 3 | Twentieth Century Fox | false |
| 15 | Mr. Destiny | - | - | - | $9,710,085 | 1,025 | $15,379,253 | Oct 12 | Walt Disney Studios Motion Pictures | false |
| 16 | Men at Work | - | - | - | $9,606,691 | 1,035 | $16,247,964 | Aug 24 | Triumph Releasing Corporation | false |
| 17 | Quigley Down Under | - | - | - | $8,627,090 | 1,094 | $21,413,105 | Oct 19 | Metro-Goldwyn-Mayer (MGM) | false |
| 18 | Die Hard 2 | - | - | - | $8,323,784 | 2,507 | $117,540,947 | Jul 6 | Twentieth Century Fox | false |
| 19 | Funny About Love | - | - | - | $8,141,292 | 1,213 | $8,141,292 | Sep 21 | Paramount Pictures | false |
| 20 | Taking Care of Business | - | - | - | $7,764,755 | 1,176 | $20,005,435 | Aug 17 | Walt Disney Studios Motion Pictures | false |
| 21 | Avalon | - | - | - | $7,098,894 | 635 | $15,740,796 | Oct 5 | TriStar Pictures | false |
| 22 | My Blue Heaven | - | - | - | $6,643,716 | 1,868 | $23,591,472 | Aug 17 | Warner Bros. | false |
| 23 | Henry & June | - | - | - | $6,603,173 | 295 | $11,567,449 | Oct 5 | Universal Pictures | false |
| 24 | Air America | - | - | - | $6,592,726 | 1,902 | $31,053,601 | Aug 10 | TriStar Pictures | false |
| 25 | Graveyard Shift | - | - | - | $6,489,180 | 1,603 | $11,582,891 | Oct 26 | Paramount Pictures | false |
| 26 | Pump Up the Volume | - | - | - | $6,426,226 | 821 | $11,541,758 | Aug 24 | New Line Cinema | false |
| 27 | Wild at Heart | - | - | - | $6,204,937 | 625 | $14,560,247 | Aug 17 | The Samuel Goldwyn Company | false |
| 28 | The Exorcist III | - | - | - | $6,179,241 | 1,414 | $26,098,824 | Aug 17 | Twentieth Century Fox | false |
| 29 | White Palace | - | - | - | $6,063,606 | 892 | $17,487,531 | Oct 19 | Universal Pictures | false |
| 30 | Hardware | - | - | - | $5,728,953 | 695 | $5,728,953 | Sep 14 | Miramax | false |
| 31 | The Witches | - | - | - | $5,398,490 | 879 | $10,360,553 | Aug 24 | Warner Bros. | false |
| 32 | Pretty Woman | - | - | - | $5,328,282 | 1,811 | $178,406,268 | Mar 23 | Walt Disney Studios Motion Pictures | false |
| 33 | Sibling Rivalry | - | - | - | $5,176,263 | 1,455 | $17,854,933 | Oct 26 | Columbia Pictures | false |
| 34 | Night of the Living Dead | - | - | - | $5,029,228 | 1,544 | $5,835,247 | Oct 19 | Columbia Pictures | false |
| 35 | Dark Angel | - | - | - | $4,348,368 | 1,041 | $4,348,368 | Sep 28 | Triumph Releasing Corporation | false |
| 36 | Welcome Home, Roxy Carmichael | - | - | - | $3,989,297 | 635 | $3,989,297 | Oct 12 | Paramount Pictures | false |
| 37 | Miller's Crossing | - | - | - | $3,768,462 | 289 | $5,080,409 | Sep 21 | Twentieth Century Fox | false |
| 38 | Delta Force 2: The Colombian Connection | - | - | - | $3,036,767 | 909 | $6,698,361 | Aug 24 | Metro-Goldwyn-Mayer (MGM) | false |
| 39 | Desperate Hours | - | - | - | $2,742,912 | 1,033 | $2,742,912 | Oct 5 | Metro-Goldwyn-Mayer (MGM) | false |
| 40 | Total Recall | - | - | - | $2,734,844 | 2,131 | $119,394,840 | Jun 1 | Sony Pictures Releasing | false |
| 41 | White Hunter Black Heart | - | - | - | $2,319,124 | 78 | $2,319,124 | Sep 14 | Warner Bros. | false |
| 42 | Texasville | - | - | - | $2,268,181 | 354 | $2,268,181 | Sep 28 | Columbia Pictures | false |
| 43 | The Lemon Sisters | - | - | - | $2,209,157 | 598 | $3,473,905 | Aug 31 | Miramax | false |
| 44 | Def by Temptation | - | - | - | $2,135,997 | 57 | $2,218,579 | May 11 | Troma | false |
| 45 | After Dark, My Sweet | - | - | - | $2,096,892 | 153 | $2,678,414 | Aug 24 | Avenue Pictures Productions | false |
| 46 | State of Grace | - | - | - | $1,911,542 | 335 | $1,911,542 | Sep 14 | Orion Pictures | false |
| 47 | Jesus of Montreal | - | - | - | $1,575,522 | 21 | $1,601,612 | May 25 | Orion Classics | false |
| 48 | May Fools | - | - | - | $1,542,130 | 30 | $1,576,702 | Jun 22 | Orion Classics | false |
| 49 | King of New York | - | - | - | $1,538,733 | 119 | $2,554,476 | Sep 28 | New Line Cinema | false |
| 50 | Repossessed | - | - | - | $1,382,462 | 115 | $1,382,462 | Sep 14 | New Line Cinema | false |
| 51 | Bloodfist II | - | - | - | $1,292,323 | 92 | $1,292,323 | Oct 12 | Concorde Pictures | false |
| 52 | Slumber Party Massacre III | - | - | - | $1,242,995 | 81 | $1,242,995 | Sep 7 | Concorde Pictures | false |
| 53 | The Icicle Thief | - | - | - | $1,197,430 | 22 | $1,231,622 | Aug 24 | Aries Films | false |
| 54 | The Boyfriend School | - | - | - | $1,171,762 | 177 | $1,171,762 | Sep 21 | Hemdale | false |
| 55 | Corporate Affairs | - | - | - | $1,006,575 | 57 | $1,006,575 | Oct 5 | Concorde Pictures | false |
| 56 | Reversal of Fortune | - | - | - | $996,482 | 661 | $15,445,131 | Oct 19 | Warner Bros. | false |
| 57 | The Hot Spot | - | - | - | $889,471 | 365 | $1,293,976 | Oct 12 | Orion Pictures | false |
| 58 | The Tall Guy | - | - | - | $510,712 | 41 | $510,712 | Sep 21 | Miramax | false |
| 59 | Tune in Tomorrow... | - | - | - | $86,635 | 207 | $1,794,001 | Oct 26 | Cinecom Pictures | false |
| 60 | Fools of Fortune | - | - | - | $83,490 | 9 | $83,490 | Sep 14 | New Line Cinema | false |
| 61 | The Spirit of '76 | - | - | - | $52,310 | 12 | $52,310 | Oct 12 | Columbia Pictures | false |
| 62 | The Nasty Girl | - | - | - | $30,574 | 40 | $2,281,569 | Oct 26 | Miramax | false |
| 63 | To Sleep with Anger | - | - | - | $26,349 | 23 | $1,161,135 | Oct 12 | The Samuel Goldwyn Company | false |
