| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Cocktail | - | - | - | $22,309,947 | 1,462 | $78,222,753 | Jul 29 | Walt Disney Studios Motion Pictures | false |
| 2 | A Fish Called Wanda | - | - | - | $21,529,544 | 1,223 | $62,493,712 | Jul 15 | Metro-Goldwyn-Mayer (MGM) | false |
| 3 | Alien Nation | - | - | - | $20,948,375 | 1,436 | $25,216,243 | Oct 7 | Twentieth Century Fox | false |
| 4 | Die Hard | - | - | - | $19,562,596 | 1,713 | $83,008,852 | Jul 15 | Twentieth Century Fox | false |
| 5 | Gorillas in the Mist | - | - | - | $18,409,915 | 1,085 | $24,720,479 | Sep 23 | Universal Pictures | false |
| 6 | Young Guns | - | - | - | $18,023,851 | 1,416 | $45,661,556 | Aug 12 | Twentieth Century Fox | false |
| 7 | Big | - | - | - | $17,967,437 | 1,419 | $114,968,774 | Jun 3 | Twentieth Century Fox | false |
| 8 | A Nightmare on Elm Street 4: The Dream Master | - | - | - | $17,354,639 | 1,767 | $49,369,899 | Aug 19 | New Line Cinema | false |
| 9 | Punchline | - | - | - | $16,124,018 | 917 | $21,042,667 | Sep 30 | Columbia Pictures | false |
| 10 | Who Framed Roger Rabbit | - | - | - | $15,608,169 | 1,598 | $156,452,370 | Jun 24 | Walt Disney Studios Motion Pictures | false |
| 11 | The Accused | - | - | - | $15,285,537 | 930 | $32,078,318 | Oct 14 | Paramount Pictures | false |
| 12 | Betrayed | - | - | - | $14,425,839 | 1,101 | $25,816,139 | Aug 26 | United Artists | false |
| 13 | Halloween 4: The Return of Michael Myers | - | - | - | $14,301,398 | 1,692 | $17,768,757 | Oct 21 | - | false |
| 14 | Coming to America | - | - | - | $11,537,542 | 2,064 | $128,152,301 | Jun 29 | Paramount Pictures | false |
| 15 | Moon Over Parador | - | - | - | $11,444,204 | 1,145 | $11,444,204 | Sep 9 | Universal Pictures | false |
| 16 | Crossing Delancey | - | - | - | $11,242,527 | 303 | $16,262,415 | Aug 26 | Warner Bros. | false |
| 17 | Married to the Mob | - | - | - | $10,530,684 | 828 | $21,486,757 | Aug 19 | Orion Pictures | false |
| 18 | Dead Ringers | - | - | - | $8,038,508 | 1,048 | $8,038,508 | Sep 23 | Twentieth Century Fox | false |
| 19 | Tucker: The Man and His Dream | - | - | - | $6,049,522 | 720 | $19,652,638 | Aug 12 | Paramount Pictures | false |
| 20 | Elvira: Mistress of the Dark | - | - | - | $5,596,267 | 627 | $5,596,267 | Sep 30 | New World Pictures | false |
| 21 | Heartbreak Hotel | - | - | - | $5,509,417 | 1,414 | $5,509,417 | Sep 30 | Walt Disney Studios Motion Pictures | false |
| 22 | Midnight Run | - | - | - | $5,041,528 | 1,161 | $38,413,606 | Jul 22 | Universal Pictures | false |
| 23 | Eight Men Out | - | - | - | $4,933,939 | 349 | $5,680,515 | Sep 2 | Orion Pictures | false |
| 24 | The Last Temptation of Christ | - | - | - | $4,537,604 | 123 | $8,373,585 | Aug 12 | Universal Pictures | false |
| 25 | Sweet Hearts Dance | - | - | - | $3,790,493 | 246 | $3,790,493 | Sep 23 | TriStar Pictures | false |
| 26 | Imagine: John Lennon | - | - | - | $3,753,977 | 561 | $3,753,977 | Oct 7 | Warner Bros. | false |
| 27 | Memories of Me | - | - | - | $3,583,303 | 723 | $3,965,604 | Sep 30 | Metro-Goldwyn-Mayer (MGM) | false |
| 28 | Tougher Than Leather | - | - | - | $3,582,760 | 130 | $3,582,760 | Sep 16 | New Line Cinema | false |
| 29 | Things Change | - | - | - | $3,527,886 | 99 | $3,527,886 | Oct 21 | Columbia Pictures | false |
| 30 | Clara's Heart | - | - | - | $3,406,299 | 315 | $5,194,491 | Oct 7 | Warner Bros. | false |
| 31 | Mystic Pizza | - | - | - | $3,340,769 | 440 | $12,793,213 | Oct 21 | The Samuel Goldwyn Company | false |
| 32 | Messenger of Death | - | - | - | $3,074,681 | 450 | $3,074,681 | Sep 16 | Cannon Film Distributors | false |
| 33 | Running on Empty | - | - | - | $2,835,116 | 238 | $2,835,116 | Sep 9 | Warner Bros. | false |
| 34 | Without a Clue | - | - | - | $2,792,963 | 491 | $8,539,181 | Oct 21 | Orion Pictures | false |
| 35 | Bat*21 | - | - | - | $2,687,824 | 516 | $3,966,256 | Oct 21 | TriStar Pictures | false |
| 36 | Stealing Home | - | - | - | $2,578,844 | 985 | $7,467,504 | Aug 26 | Warner Bros. | false |
| 37 | Kansas | - | - | - | $2,432,536 | 847 | $2,432,536 | Sep 23 | Trans World Entertainment (TWE) | false |
| 38 | A World Apart | - | - | - | $2,291,025 | 42 | $2,326,860 | Jun 17 | Atlantic Releasing Corporation | false |
| 39 | Pumpkinhead | - | - | - | $2,132,666 | 353 | $3,385,516 | Oct 14 | United Artists | false |
| 40 | Hot to Trot | - | - | - | $1,999,841 | 1,157 | $6,436,211 | Aug 26 | Warner Bros. | false |
| 41 | Hero and the Terror | - | - | - | $1,841,985 | 995 | $5,301,200 | Aug 26 | Cannon Film Distributors | false |
| 42 | Feds | - | - | - | $1,835,007 | 850 | $3,838,793 | Oct 28 | Warner Bros. | false |
| 43 | A Handful of Dust | - | - | - | $1,504,492 | 29 | $1,560,700 | Jun 24 | New Line Cinema | false |
| 44 | Pascali's Island | - | - | - | $1,410,331 | 55 | $1,451,857 | Jul 22 | Avenue Pictures Productions | false |
| 45 | Patty Hearst | - | - | - | $1,223,326 | 460 | $1,223,326 | Sep 23 | Atlantic Releasing Corporation | false |
| 46 | Mr. North | - | - | - | $1,164,822 | 29 | $1,221,366 | Jul 22 | The Samuel Goldwyn Company | false |
| 47 | The Thin Blue Line | - | - | - | $1,117,100 | 23 | $1,209,846 | Aug 26 | Miramax | false |
| 48 | Spellbinder | - | - | - | $657,446 | 326 | $657,446 | Sep 23 | Metro-Goldwyn-Mayer (MGM) | false |
| 49 | Track 29 | - | - | - | $429,028 | 13 | $429,028 | Sep 9 | Island Pictures | false |
| 50 | Tapeheads | - | - | - | $343,786 | 138 | $343,786 | Oct 21 | Avenue Pictures Productions | false |
| 51 | The Deceivers | - | - | - | $333,184 | 68 | $346,297 | Sep 2 | Cinecom Pictures | false |
| 52 | Madame Sousatzka | - | - | - | $251,083 | 123 | $3,548,238 | Oct 14 | Universal Pictures | false |
| 53 | The Year My Voice Broke | - | - | - | $203,548 | 20 | $213,901 | Aug 25 | Avenue Pictures Productions | false |
| 54 | Miles from Home | - | - | - | $188,964 | 32 | $188,964 | Sep 16 | Cinecom Pictures | false |
| 55 | Seven Hours to Judgment | - | - | - | $177,820 | 73 | $177,820 | Sep 16 | Trans World Entertainment (TWE) | false |
| 56 | Rocket Gibraltar | - | - | - | $146,803 | 5 | $187,349 | Sep 2 | Columbia Pictures | false |
| 57 | Another Woman | - | - | - | $115,962 | 24 | $1,562,749 | Oct 14 | Orion Pictures | false |
| 58 | Salaam Bombay! | - | - | - | $44,672 | 27 | $2,080,046 | Oct 7 | Cinecom Pictures | false |
| 59 | Bird | - | - | - | $42,800 | 93 | $2,181,286 | Sep 30 | Warner Bros. | false |
| 60 | The Lair of the White Worm | - | - | - | $33,762 | 32 | $1,189,315 | Oct 21 | Vestron Pictures | false |
| 61 | Some Girls | - | - | - | $17,430 | 23 | $401,421 | Sep 9 | Metro-Goldwyn-Mayer (MGM) | false |
| 62 | The Prince of Pennsylvania | - | - | - | $5,415 | 1 | $5,415 | Sep 16 | New Line Cinema | false |
