| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Fatal Attraction | - | - | - | $78,615,084 | 1,401 | $156,645,693 | Sep 18 | Paramount Pictures | false |
| 2 | Like Father Like Son | - | - | - | $26,658,566 | 1,277 | $34,377,585 | Oct 2 | TriStar Pictures | false |
| 3 | Dirty Dancing | - | - | - | $24,856,184 | 1,012 | $63,446,382 | Aug 21 | Vestron Pictures | false |
| 4 | Stakeout | - | - | - | $24,376,410 | 1,364 | $65,673,233 | Aug 7 | Walt Disney Studios Motion Pictures | false |
| 5 | The Principal | - | - | - | $19,734,940 | 1,196 | $19,734,940 | Sep 18 | TriStar Pictures | false |
| 6 | The Princess Bride | - | - | - | $17,017,016 | 803 | $30,857,814 | Sep 25 | Twentieth Century Fox | false |
| 7 | No Way Out | - | - | - | $14,686,094 | 1,130 | $35,509,515 | Aug 14 | Orion Pictures | false |
| 8 | Hellraiser | - | - | - | $14,564,027 | 1,104 | $14,564,027 | Sep 18 | New World Pictures | false |
| 9 | The Pick-up Artist | - | - | - | $13,290,368 | 1,132 | $13,290,368 | Sep 18 | Twentieth Century Fox | false |
| 10 | La Bamba | - | - | - | $13,120,687 | 1,251 | $54,215,416 | Jul 24 | Columbia Pictures | false |
| 11 | Can't Buy Me Love | - | - | - | $10,501,777 | 1,283 | $31,623,833 | Aug 14 | Walt Disney Studios Motion Pictures | false |
| 12 | The Big Easy | - | - | - | $10,039,238 | 1,219 | $17,685,307 | Aug 21 | Columbia Pictures | false |
| 13 | Baby Boom | - | - | - | $9,617,374 | 892 | $26,712,476 | Oct 9 | United Artists | false |
| 14 | Prince of Darkness | - | - | - | $9,576,010 | 1,239 | $14,182,492 | Oct 23 | Universal Pictures | false |
| 15 | Someone to Watch Over Me | - | - | - | $9,266,200 | 894 | $10,278,549 | Oct 9 | Columbia Pictures | false |
| 16 | Suspect | - | - | - | $8,881,826 | 1,029 | $18,782,400 | Oct 23 | TriStar Pictures | false |
| 17 | RoboCop | - | - | - | $6,841,498 | 1,601 | $53,424,681 | Jul 17 | Orion Pictures | false |
| 18 | Hamburger Hill | - | - | - | $6,821,165 | 814 | $13,839,404 | Aug 28 | Paramount Pictures | false |
| 19 | Born in East L.A. | - | - | - | $6,002,158 | 1,112 | $17,355,263 | Aug 21 | Universal Pictures | false |
| 20 | Surrender | - | - | - | $5,711,976 | 1,067 | $5,711,976 | Oct 9 | Warner Bros. | false |
| 21 | The Lost Boys | - | - | - | $5,541,690 | 1,249 | $32,222,567 | Jul 31 | Warner Bros. | false |
| 22 | The Fourth Protocol | - | - | - | $5,397,104 | 1,061 | $12,423,831 | Aug 28 | Lorimar Motion Pictures | false |
| 23 | The Living Daylights | - | - | - | $5,008,420 | 1,728 | $51,185,897 | Jul 31 | United Artists | false |
| 24 | Best Seller | - | - | - | $4,278,150 | 253 | $4,278,150 | Sep 25 | Orion Pictures | false |
| 25 | Fatal Beauty | - | - | - | $3,792,085 | 1,117 | $12,046,526 | Oct 30 | Metro-Goldwyn-Mayer (MGM) | false |
| 26 | Three O'Clock High | - | - | - | $3,685,862 | 849 | $3,685,862 | Oct 9 | Universal Pictures | false |
| 27 | The Hidden | - | - | - | $3,493,424 | 1,045 | $9,747,988 | Oct 30 | New Line Cinema | false |
| 28 | Big Shots | - | - | - | $3,390,043 | 932 | $3,390,043 | Oct 2 | Twentieth Century Fox | false |
| 29 | The Sicilian | - | - | - | $3,371,748 | 370 | $5,406,879 | Oct 23 | Twentieth Century Fox | false |
| 30 | Near Dark | - | - | - | $3,369,307 | 429 | $3,369,307 | Oct 2 | De Laurentiis Entertainment Group (DEG) | false |
| 31 | Barfly | - | - | - | $3,221,568 | 2 | $3,221,568 | Oct 16 | Cannon Film Distributors | false |
| 32 | Wish You Were Here | - | - | - | $3,206,252 | 43 | $3,283,832 | Jul 24 | Atlantic Releasing Corporation | false |
| 33 | House II: The Second Story | - | - | - | $2,912,118 | 1,069 | $7,800,000 | Aug 28 | New World Pictures | false |
| 34 | No Man's Land | - | - | - | $2,877,571 | 510 | $2,877,571 | Oct 23 | Orion Pictures | false |
| 35 | Hello Mary Lou: Prom Night II | - | - | - | $2,683,519 | 343 | $2,683,519 | Oct 16 | The Samuel Goldwyn Company | false |
| 36 | House of Games | - | - | - | $2,585,639 | 9 | $2,585,639 | Oct 16 | Orion Pictures | false |
| 37 | Maurice | - | - | - | $2,438,304 | 1 | $2,438,304 | Sep 18 | Cinecom Pictures | false |
| 38 | Maid to Order | - | - | - | $2,118,172 | 522 | $9,868,521 | Jul 31 | New Century | false |
| 39 | The Curse | - | - | - | $1,930,001 | 326 | $1,930,001 | Sep 11 | Trans World Entertainment (TWE) | false |
| 40 | The Big Town | - | - | - | $1,733,017 | 762 | $1,733,017 | Sep 25 | Columbia Pictures | false |
| 41 | Matewan | - | - | - | $1,641,247 | 42 | $1,680,358 | Aug 28 | Cinecom Pictures | false |
| 42 | The Whistle Blower | - | - | - | $1,447,473 | 62 | $1,500,000 | Jul 10 | Hemdale | false |
| 43 | A Prayer for the Dying | - | - | - | $1,432,687 | 407 | $1,432,687 | Sep 11 | The Samuel Goldwyn Company | false |
| 44 | China Girl | - | - | - | $1,262,091 | 193 | $1,262,091 | Sep 25 | Vestron Pictures | false |
| 45 | Dancers | - | - | - | $1,190,416 | 12 | $1,190,416 | Oct 9 | Cannon Film Distributors | false |
| 46 | Real Men | - | - | - | $873,903 | 150 | $873,903 | Sep 25 | United Artists | false |
| 47 | Chuck Berry: Hail! Hail! Rock 'n' Roll | - | - | - | $719,323 | 33 | $719,323 | Oct 9 | Universal Pictures | false |
| 48 | Weeds | - | - | - | $710,974 | 86 | $2,325,444 | Oct 16 | De Laurentiis Entertainment Group (DEG) | false |
| 49 | In the Mood | - | - | - | $682,881 | 361 | $999,382 | Sep 16 | Lorimar Motion Pictures | false |
| 50 | Amazon Women on the Moon | - | - | - | $548,696 | 50 | $548,696 | Sep 18 | Universal Pictures | false |
| 51 | Man on Fire | - | - | - | $519,596 | 178 | $519,596 | Oct 9 | TriStar Pictures | false |
| 52 | Oviri | - | - | - | $518,520 | 16 | $583,800 | Jul 31 | International Film Marketing | false |
| 53 | Slam Dance | - | - | - | $406,881 | 47 | $406,881 | Oct 2 | Island Pictures | false |
| 54 | Orphans | - | - | - | $252,430 | 25 | $252,430 | Sep 18 | Lorimar Motion Pictures | false |
| 55 | Witness in the War Zone | - | - | - | $141,211 | 46 | $141,211 | Sep 11 | Skouras Pictures | false |
| 56 | Sammy and Rosie Get Laid | - | - | - | $55,308 | 15 | $1,196,336 | Oct 30 | Cinecom Pictures | false |
| 57 | I've Heard the Mermaids Singing | - | - | - | $39,840 | 27 | $1,408,491 | Sep 11 | Miramax | false |
| 58 | Hope and Glory | - | - | - | $38,293 | 328 | $10,021,120 | Oct 16 | Columbia Pictures | false |
| 59 | Zombie High | - | - | - | $21,905 | 25 | $21,905 | Oct 2 | Palisades Pictures | false |
