
The Substance
A fading celebrity takes a black-market drug: a cell-replicating substance that helps her create a younger, better version of herself.
| Domestic | |||
|---|---|---|---|
| Market | Release Date | Opening | Gross |
| Domestic | Sep 20, 2024 | $3,205,212 | $17,584,795 |
| Europe, Middle East, and Africa | |||
|---|---|---|---|
| Market | Release Date | Opening | Gross |
| Angola | Sep 19, 2024 | – | – |
| Austria | Sep 20, 2024 | – | $320,659 |
| Belgium | Nov 6, 2024 | – | $680,713 |
| Bulgaria | Jan 17, 2025 | $8,234 | $44,595 |
| Croatia | Sep 19, 2024 | $15,516 | $93,649 |
| Czech Republic | Oct 17, 2024 | $35,217 | $250,072 |
| Denmark | Oct 25, 2024 | – | $334,051 |
| Estonia | Oct 31, 2024 | – | $124,928 |
| Finland | Sep 27, 2024 | – | $584,873 |
| France | Nov 6, 2024 | $1,188,864 | $4,170,555 |
| Germany | Sep 19, 2024 | – | $1,708,525 |
| Greece | Oct 31, 2024 | – | $339,783 |
| Hungary | Oct 10, 2024 | $73,662 | $328,795 |
| Iceland | Oct 11, 2024 | $4,449 | $69,744 |
| Israel | Nov 21, 2024 | – | $165,312 |
| Italy | Aug 31, 2024 | – | $3,054,351 |
| Latvia | Oct 25, 2024 | – | $125,413 |
| Lithuania | Sep 27, 2024 | $24,413 | $154,696 |
| Netherlands | Sep 19, 2024 | $232,367 | $2,257,514 |
| Norway | Sep 20, 2024 | $46,146 | $340,074 |
| Poland | Sep 20, 2024 | $197,867 | $2,304,986 |
| Portugal | Oct 31, 2024 | $119,473 | $485,748 |
| Romania | Jan 10, 2025 | $55,733 | $222,924 |
| Serbia and Montenegro | Sep 19, 2024 | $15,852 | $112,003 |
| Slovakia | Oct 10, 2024 | $16,190 | $63,731 |
| Slovenia | Dec 19, 2024 | $3,570 | $18,110 |
| Spain | Oct 11, 2024 | $490,373 | $3,631,454 |
| Sweden | Sep 18, 2024 | – | $474,473 |
| Switzerland | Sep 19, 2024 | – | $633,392 |
| Türkiye | Nov 1, 2024 | $9,774 | $87,618 |
| Ukraine | Oct 10, 2024 | – | $439,483 |
| United Kingdom | Sep 20, 2024 | $787,762 | $5,128,067 |
| Latin America | |||
|---|---|---|---|
| Market | Release Date | Opening | Gross |
| Central America | Sep 19, 2024 | – | – |
| Colombia | Sep 19, 2024 | $43,672 | $1,746,725 |
| Mexico | Sep 19, 2024 | $638,577 | $10,055,203 |
| Asia Pacific | |||
|---|---|---|---|
| Market | Release Date | Opening | Gross |
| Australia | Sep 19, 2024 | $211,930 | $1,859,759 |
| Hong Kong | Oct 10, 2024 | $216,467 | $910,315 |
| Indonesia | Oct 16, 2024 | – | $146,745 |
| Japan | May 16, 2025 | $390,040 | $422,966 |
| New Zealand | Sep 19, 2024 | $42,094 | $244,851 |
| Philippines | Sep 25, 2024 | – | $196,008 |
| Russia/CIS | Sep 18, 2024 | $344,247 | $6,510,530 |
| Singapore | Sep 26, 2024 | – | $131,367 |
| South Korea | Dec 11, 2024 | $232,785 | $3,726,947 |
| Taiwan | Oct 18, 2024 | – | $686,322 |
| Thailand | Sep 26, 2024 | – | $769,828 |
| Vietnam | Nov 1, 2024 | $57,033 | $261,566 |
