| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Home Alone | - | - | - | $99,024,353 | 2,173 | $285,761,243 | 34.7% | Nov 16, 1990 | Twentieth Century Fox |
| 2 | Ghost | - | - | - | $48,401,569 | 1,766 | $217,631,306 | 22.2% | Jul 13, 1990 | Paramount Pictures |
| 3 | Marked for Death | - | - | - | $46,044,396 | 1,974 | $46,044,396 | 100% | Oct 5, 1990 | Twentieth Century Fox |
| 4 | Three Men and a Little Lady | - | - | - | $39,821,562 | 1,614 | $71,609,321 | 55.6% | Nov 21, 1990 | Walt Disney Studios Motion Pictures |
| 5 | Dances with Wolves | - | - | - | $38,517,859 | 1,636 | $184,208,848 | 20.9% | Nov 9, 1990 | Orion Pictures |
| 6 | Rocky V | - | - | - | $36,106,731 | 2,106 | $40,946,358 | 88.2% | Nov 16, 1990 | United Artists |
| 7 | Child's Play 2 | - | - | - | $28,501,605 | 2,017 | $28,501,605 | 100% | Nov 9, 1990 | Universal Pictures |
| 8 | Memphis Belle | - | - | - | $27,441,977 | 1,368 | $27,441,977 | 100% | Oct 12, 1990 | Warner Bros. |
| 9 | Misery | - | - | - | $26,144,732 | 1,370 | $61,276,872 | 42.7% | Nov 30, 1990 | Columbia Pictures |
| 10 | Jacob's Ladder | - | - | - | $26,118,851 | 1,264 | $26,118,851 | 100% | Nov 2, 1990 | TriStar Pictures |
| 11 | Pacific Heights | - | - | - | $25,539,132 | 1,291 | $29,381,956 | 86.9% | Sep 28, 1990 | Twentieth Century Fox |
| 12 | Fantasia 1990 Re-release | - | - | - | $25,363,371 | 481 | $25,363,371 | 100% | Oct 5, 1990 | Walt Disney Studios Motion Pictures |
| 13 | Goodfellas | - | - | - | $25,069,662 | 1,328 | $46,836,214 | 53.5% | Sep 19, 1990 | Warner Bros. |
| 14 | Predator 2 | - | - | - | $25,043,445 | 1,978 | $30,669,413 | 81.7% | Nov 21, 1990 | Twentieth Century Fox |
| 15 | Quigley Down Under | - | - | - | $21,413,105 | 1,094 | $21,413,105 | 100% | Oct 19, 1990 | Metro-Goldwyn-Mayer (MGM) |
| 16 | Sibling Rivalry | - | - | - | $17,854,933 | 1,455 | $17,854,933 | 100% | Oct 26, 1990 | Columbia Pictures |
| 17 | Postcards from the Edge | - | - | - | $17,617,988 | 1,323 | $39,071,603 | 45.1% | Sep 14, 1990 | Columbia Pictures |
| 18 | White Palace | - | - | - | $17,487,531 | 892 | $17,487,531 | 100% | Oct 19, 1990 | Universal Pictures |
| 19 | Avalon | - | - | - | $15,740,796 | 635 | $15,740,796 | 100% | Oct 5, 1990 | TriStar Pictures |
| 20 | Reversal of Fortune | - | - | - | $15,445,131 | 661 | $15,445,131 | 100% | Oct 19, 1990 | Warner Bros. |
| 21 | Mr. Destiny | - | - | - | $15,379,253 | 1,025 | $15,379,253 | 100% | Oct 12, 1990 | Walt Disney Studios Motion Pictures |
| 22 | The Rescuers Down Under | - | - | - | $14,872,759 | 1,487 | $27,931,461 | 53.2% | Nov 16, 1990 | Walt Disney Studios Motion Pictures |
| 23 | Graveyard Shift | - | - | - | $11,582,891 | 1,603 | $11,582,891 | 100% | Oct 26, 1990 | Paramount Pictures |
| 24 | Henry & June | - | - | - | $11,567,449 | 295 | $11,567,449 | 100% | Oct 5, 1990 | Universal Pictures |
| 25 | The Rookie | - | - | - | $10,867,857 | 1,862 | $21,633,874 | 50.2% | Dec 7, 1990 | Warner Bros. |
| 26 | Flatliners | - | - | - | $8,551,745 | 1,483 | $61,489,265 | 13.9% | Aug 10, 1990 | Columbia Pictures |
| 27 | Look Who's Talking Too | - | - | - | $7,249,825 | 1,647 | $47,789,074 | 15.2% | Dec 14, 1990 | TriStar Pictures |
| 28 | Edward Scissorhands | - | - | - | $6,436,182 | 1,372 | $56,362,352 | 11.4% | Dec 7, 1990 | Twentieth Century Fox |
| 29 | Presumed Innocent | - | - | - | $6,319,337 | 1,451 | $86,303,188 | 7.3% | Jul 27, 1990 | Warner Bros. |
| 30 | Death Warrant | - | - | - | $5,862,727 | 1,090 | $16,853,487 | 34.8% | Sep 14, 1990 | Metro-Goldwyn-Mayer (MGM) |
| 31 | Night of the Living Dead | - | - | - | $5,835,247 | 1,544 | $5,835,247 | 100% | Oct 19, 1990 | Columbia Pictures |
| 32 | Narrow Margin | - | - | - | $5,142,635 | 1,253 | $10,873,237 | 47.3% | Sep 21, 1990 | TriStar Pictures |
| 33 | Miller's Crossing | - | - | - | $5,006,463 | 289 | $5,080,409 | 98.5% | Sep 21, 1990 | Twentieth Century Fox |
| 34 | Graffiti Bridge | - | - | - | $4,562,778 | 688 | $4,562,778 | 100% | Nov 2, 1990 | Warner Bros. |
| 35 | Pretty Woman | - | - | - | $4,444,517 | 1,811 | $178,406,268 | 2.5% | Mar 23, 1990 | Walt Disney Studios Motion Pictures |
| 36 | Welcome Home, Roxy Carmichael | - | - | - | $3,989,297 | 635 | $3,989,297 | 100% | Oct 12, 1990 | Paramount Pictures |
| 37 | Funny About Love | - | - | - | $3,609,256 | 1,213 | $8,141,292 | 44.3% | Sep 21, 1990 | Paramount Pictures |
| 38 | Mermaids | - | - | - | $3,590,085 | 1,154 | $35,419,397 | 10.1% | Dec 14, 1990 | Orion Pictures |
| 39 | Dark Angel | - | - | - | $3,239,119 | 1,041 | $4,348,368 | 74.5% | Sep 28, 1990 | Triumph Releasing Corporation |
| 40 | Desperate Hours | - | - | - | $2,742,912 | 1,033 | $2,742,912 | 100% | Oct 5, 1990 | Metro-Goldwyn-Mayer (MGM) |
| 41 | King of New York | - | - | - | $2,307,726 | 119 | $2,554,476 | 90.3% | Sep 28, 1990 | New Line Cinema |
| 42 | Havana | - | - | - | $2,234,815 | 835 | $9,243,140 | 24.2% | Dec 14, 1990 | Universal Pictures |
| 43 | Def by Temptation | - | - | - | $2,135,997 | 57 | $2,218,579 | 96.3% | May 11, 1990 | Troma |
| 44 | The Krays | - | - | - | $2,060,847 | 392 | $2,060,847 | 100% | Nov 9, 1990 | Miramax |
| 45 | Texasville | - | - | - | $1,795,817 | 354 | $2,268,181 | 79.2% | Sep 28, 1990 | Columbia Pictures |
| 46 | Tune in Tomorrow... | - | - | - | $1,794,001 | 207 | $1,794,001 | 100% | Oct 26, 1990 | Cinecom Pictures |
| 47 | The Nutcracker Prince | - | - | - | $1,781,694 | 906 | $1,781,694 | 100% | Nov 21, 1990 | Warner Bros. |
| 48 | The Hot Spot | - | - | - | $1,293,976 | 365 | $1,293,976 | 100% | Oct 12, 1990 | Orion Pictures |
| 49 | Bloodfist II | - | - | - | $1,292,323 | 92 | $1,292,323 | 100% | Oct 12, 1990 | Concorde Pictures |
| 50 | Robot Jox | - | - | - | $1,272,977 | 333 | $1,272,977 | 100% | Nov 21, 1990 | Triumph Releasing Corporation |
| 51 | The Icicle Thief | - | - | - | $1,197,430 | 22 | $1,231,622 | 97.2% | Aug 24, 1990 | Aries Films |
| 52 | To Sleep with Anger | - | - | - | $1,161,135 | 23 | $1,161,135 | 100% | Oct 12, 1990 | The Samuel Goldwyn Company |
| 53 | Corporate Affairs | - | - | - | $1,006,575 | 57 | $1,006,575 | 100% | Oct 5, 1990 | Concorde Pictures |
| 54 | State of Grace | - | - | - | $989,212 | 335 | $1,911,542 | 51.7% | Sep 14, 1990 | Orion Pictures |
| 55 | Waiting for the Light | - | - | - | $808,690 | 149 | $808,690 | 100% | Nov 2, 1990 | Triumph Releasing Corporation |
| 56 | C'est la vie | - | - | - | $805,472 | 28 | $805,472 | 100% | Nov 2, 1990 | The Samuel Goldwyn Company |
| 57 | The Return of Superfly | - | - | - | $610,402 | 260 | $610,402 | 100% | Nov 9, 1990 | Triton Pictures |
| 58 | The Tall Guy | - | - | - | $385,787 | 41 | $510,712 | 75.5% | Sep 21, 1990 | Miramax |
| 59 | Frankenstein Unbound | - | - | - | $334,748 | 34 | $334,748 | 100% | Nov 2, 1990 | Twentieth Century Fox |
| 60 | The Sheltering Sky | - | - | - | $120,880 | 95 | $2,075,084 | 5.8% | Dec 14, 1990 | Warner Bros. |
| 61 | The Grifters | - | - | - | $103,832 | 780 | $13,446,769 | 0.8% | Dec 7, 1990 | Miramax |
| 62 | Mr. & Mrs. Bridge | - | - | - | $98,086 | 240 | $7,698,010 | 1.3% | Nov 23, 1990 | Miramax |
| 63 | Hidden Agenda | - | - | - | $86,726 | 114 | $1,030,938 | 8.4% | Nov 21, 1990 | Hemdale |
| 64 | Fools of Fortune | - | - | - | $65,572 | 9 | $83,490 | 78.5% | Sep 14, 1990 | New Line Cinema |
| 65 | The Spirit of '76 | - | - | - | $52,310 | 12 | $52,310 | 100% | Oct 12, 1990 | Columbia Pictures |
| 66 | Vincent & Theo | - | - | - | $36,247 | 59 | $2,231,274 | 1.6% | Nov 2, 1990 | Hemdale |
| 67 | The Nasty Girl | - | - | - | $30,574 | 40 | $2,281,569 | 1.3% | Oct 26, 1990 | Miramax |
| 68 | Eating | - | - | - | $18,820 | 19 | $2,100,538 | 0.9% | Nov 16, 1990 | Rainbow Releasing |
| 69 | Just Ask for Diamond | - | - | - | $12,751 | 30 | $12,751 | 100% | Nov 30, 1990 | Castle Hill Productions |