| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Beetlejuice | - | - | - | $44,359,899 | 1,582 | $73,707,461 | 60.2% | Mar 30, 1988 | Warner Bros. |
| 2 | Biloxi Blues | - | - | - | $22,865,240 | 1,330 | $43,184,798 | 52.9% | Mar 25, 1988 | Universal Pictures |
| 3 | Bright Lights, Big City | - | - | - | $16,118,077 | 1,199 | $16,118,077 | 100% | Apr 1, 1988 | United Artists |
| 4 | The Fox and the Hound 1988 Re-release | - | - | - | $16,072,087 | 1,567 | $23,556,988 | 68.2% | Mar 25, 1988 | Walt Disney Studios Motion Pictures |
| 5 | Colors | - | - | - | $16,030,796 | 1,388 | $46,616,067 | 34.4% | Apr 15, 1988 | Orion Pictures |
| 6 | The Seventh Sign | - | - | - | $16,003,516 | 1,258 | $18,875,011 | 84.8% | Apr 1, 1988 | TriStar Pictures |
| 7 | Moonstruck | - | - | - | $12,516,872 | 1,178 | $80,640,528 | 15.5% | Dec 18, 1987 | Metro-Goldwyn-Mayer (MGM) |
| 8 | Good Morning, Vietnam | - | - | - | $12,107,541 | 1,598 | $123,922,370 | 9.8% | Dec 25, 1987 | Walt Disney Studios Motion Pictures |
| 9 | The Last Emperor | - | - | - | $11,345,950 | 877 | $43,984,230 | 25.8% | Nov 20, 1987 | Columbia Pictures |
| 10 | Above the Law | - | - | - | $10,674,477 | 868 | $18,869,631 | 56.6% | Apr 8, 1988 | Warner Bros. |
| 11 | Johnny Be Good | - | - | - | $10,235,789 | 1,194 | $17,550,399 | 58.3% | Mar 25, 1988 | Orion Pictures |
| 12 | Bad Dreams | - | - | - | $9,797,098 | 1,185 | $9,797,098 | 100% | Apr 8, 1988 | Twentieth Century Fox |
| 13 | Return to Snowy River | - | - | - | $7,607,447 | 1,121 | $13,687,027 | 55.6% | Apr 15, 1988 | Walt Disney Studios Motion Pictures |
| 14 | Police Academy 5: Assignment: Miami Beach | - | - | - | $6,982,470 | 1,700 | $19,510,371 | 35.8% | Mar 18, 1988 | Warner Bros. |
| 15 | Casual Sex? | - | - | - | $6,245,895 | 1,265 | $12,277,096 | 50.9% | Apr 22, 1988 | Universal Pictures |
| 16 | The Milagro Beanfield War | - | - | - | $5,873,573 | 437 | $13,825,794 | 42.5% | Mar 18, 1988 | Universal Pictures |
| 17 | Stand and Deliver | - | - | - | $5,829,981 | 472 | $13,994,920 | 41.7% | Mar 11, 1988 | Warner Bros. |
| 18 | Fatal Attraction | - | - | - | $5,612,019 | 1,401 | $156,645,693 | 3.6% | Sep 18, 1987 | Paramount Pictures |
| 19 | The Unbearable Lightness of Being | - | - | - | $5,242,069 | 140 | $10,006,806 | 52.4% | Feb 5, 1988 | Orion Pictures |
| 20 | Masquerade | - | - | - | $4,335,120 | 1,031 | $15,855,828 | 27.3% | Mar 11, 1988 | Metro-Goldwyn-Mayer (MGM) |
| 21 | A New Life | - | - | - | $4,246,843 | 796 | $7,721,852 | 55% | Mar 25, 1988 | Paramount Pictures |
| 22 | D.O.A. | - | - | - | $4,129,700 | 908 | $12,706,478 | 32.5% | Mar 18, 1988 | Walt Disney Studios Motion Pictures |
| 23 | The Unholy | - | - | - | $4,018,496 | 1,189 | $6,337,299 | 63.4% | Apr 22, 1988 | Vestron Pictures |
| 24 | Broadcast News | - | - | - | $3,702,642 | 848 | $51,249,404 | 7.2% | Dec 18, 1987 | Twentieth Century Fox |
| 25 | Three Men and a Baby | - | - | - | $3,259,421 | 1,813 | $167,780,960 | 1.9% | Nov 25, 1987 | Walt Disney Studios Motion Pictures |
| 26 | Hope and Glory | - | - | - | $2,755,282 | 328 | $10,021,120 | 27.5% | Oct 16, 1987 | Columbia Pictures |
| 27 | 18 Again! | - | - | - | $2,567,099 | 1,152 | $2,567,099 | 100% | Apr 8, 1988 | New World Pictures |
| 28 | Vice Versa | - | - | - | $2,387,681 | 1,225 | $13,664,060 | 17.5% | Mar 11, 1988 | Columbia Pictures |
| 29 | Hairspray | - | - | - | $2,220,353 | 227 | $6,671,108 | 33.3% | Feb 26, 1988 | New Line Cinema |
| 30 | Sunset | - | - | - | $1,096,290 | 1,024 | $4,594,452 | 23.9% | Apr 29, 1988 | TriStar Pictures |
| 31 | Critters 2: The Main Course | - | - | - | $963,519 | 1,114 | $3,813,293 | 25.3% | Apr 29, 1988 | New Line Cinema |
| 32 | Appointment with Death | - | - | - | $960,040 | 465 | $960,040 | 100% | Apr 15, 1988 | Cannon Film Distributors |
| 33 | A Time of Destiny | - | - | - | $800,905 | 220 | $1,212,487 | 66.1% | Apr 22, 1988 | Columbia Pictures |
| 34 | Lady in White | - | - | - | $358,029 | 107 | $1,705,139 | 21% | Apr 22, 1988 | New Century |
| 35 | Two Moon Junction | - | - | - | $337,800 | 458 | $1,547,397 | 21.8% | Apr 29, 1988 | Lorimar Motion Pictures |
| 36 | Plain Clothes | - | - | - | $289,323 | 193 | $289,323 | 100% | Apr 15, 1988 | Paramount Pictures |
| 37 | Sammy and Rosie Get Laid | - | - | - | $258,321 | 15 | $1,196,336 | 21.6% | Oct 30, 1987 | Cinecom Pictures |
| 38 | Mondo New York | - | - | - | $193,209 | 1 | $193,209 | 100% | Apr 22, 1988 | Fourth and Broadway |
| 39 | Little Nikita | - | - | - | $118,077 | 376 | $1,733,070 | 6.8% | Mar 18, 1988 | Columbia Pictures |
| 40 | Stormy Monday | - | - | - | $61,830 | 49 | $1,791,328 | 3.5% | Apr 22, 1988 | Atlantic Releasing Corporation |
| 41 | White Mischief | - | - | - | $47,637 | 87 | $3,107,551 | 1.5% | Apr 22, 1988 | Columbia Pictures |
| 42 | The Lighthorsemen | - | - | - | $33,779 | 16 | $33,779 | 100% | Apr 8, 1988 | Cinecom Pictures |
| 43 | The Moderns | - | - | - | $33,235 | 28 | $2,011,497 | 1.7% | Apr 15, 1988 | Alive Films |
| 44 | Bellman and True | - | - | - | $30,423 | 8 | $226,944 | 13.4% | Apr 1, 1988 | Island Pictures |
| 45 | Powaqqatsi | - | - | - | $17,655 | 22 | $589,244 | 3% | Apr 29, 1988 | Cannon Film Distributors |
| 46 | Wings of Desire | - | - | - | $13,131 | 29 | $3,210,139 | 0.4% | Apr 29, 1988 | Orion Classics |
| 47 | Consuming Passions | - | - | - | $9,552 | 5 | $118,206 | 8.1% | Apr 6, 1988 | The Samuel Goldwyn Company |
| 48 | Da | - | - | - | $7,479 | 1 | $644,532 | 1.2% | Apr 29, 1988 | FilmDallas Pictures |
