| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | A Quiet Place Part II | - | - | - | $139,269,168 | 3,744 | $160,072,261 | May 28 | Paramount Pictures | false |
| 2 | Godzilla vs. Kong | - | - | - | $89,192,760 | 3,084 | $100,916,094 | Mar 31 | Warner Bros. | false |
| 3 | F9: The Fast Saga | - | - | - | $88,163,505 | 4,203 | $173,005,945 | Jun 25 | Universal Pictures | false |
| 4 | Cruella | - | - | - | $73,413,706 | 3,922 | $86,103,234 | May 28 | Walt Disney Studios Motion Pictures | false |
| 5 | The Conjuring: The Devil Made Me Do It | - | - | - | $57,113,366 | 3,280 | $65,631,050 | Jun 4 | Warner Bros. | false |
| 6 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | - | - | - | $49,196,684 | 2,087 | $49,505,008 | Apr 23 | FUNimation Entertainment | false |
| 7 | Mortal Kombat | - | - | - | $37,354,630 | 3,114 | $42,326,031 | Apr 23 | Warner Bros. | false |
| 8 | Peter Rabbit 2: The Runaway | - | - | - | $31,422,722 | 3,346 | $40,501,717 | Jun 11 | Sony Pictures Releasing | false |
| 9 | Hitman's Wife's Bodyguard | - | - | - | $27,769,227 | 3,361 | $38,014,727 | Jun 16 | Lionsgate Films | false |
| 10 | Wrath of Man | - | - | - | $27,326,528 | 3,007 | $27,466,489 | May 7 | United Artists Releasing | false |
| 11 | Raya and the Last Dragon | - | - | - | $24,752,715 | 2,375 | $54,723,032 | Mar 5 | Walt Disney Studios Motion Pictures | false |
| 12 | Spiral | - | - | - | $23,169,064 | 2,991 | $23,216,862 | May 14 | Lionsgate Films | false |
| 13 | In the Heights | - | - | - | $22,581,509 | 3,509 | $29,975,167 | Jun 11 | Warner Bros. | false |
| 14 | Nobody | - | - | - | $18,537,560 | 2,567 | $27,568,035 | Mar 26 | Universal Pictures | false |
| 15 | Spirit Untamed | - | - | - | $16,406,150 | 3,394 | $17,716,215 | Jun 4 | Universal Pictures | false |
| 16 | The Unholy | - | - | - | $15,530,440 | 2,057 | $15,532,137 | Apr 2 | Screen Gems | false |
| 17 | Tom & Jerry | - | - | - | $7,922,728 | 2,563 | $46,536,687 | Feb 26 | Warner Bros. | false |
| 18 | Those Who Wish Me Dead | - | - | - | $6,791,716 | 3,379 | $7,407,200 | May 14 | Warner Bros. | false |
| 19 | Separation | - | - | - | $4,509,143 | 1,911 | $4,509,143 | Apr 30 | Open Road Films (II) | false |
| 20 | The Girl Who Believes in Miracles | - | - | - | $3,162,012 | 1,012 | $3,163,362 | Apr 2 | Atlas Distribution Company | false |
| 21 | Voyagers | - | - | - | $3,149,935 | 1,996 | $3,149,935 | Apr 9 | Lionsgate Films | false |
| 22 | The Courier | - | - | - | $2,883,939 | 1,641 | $6,613,432 | Mar 19 | Roadside Attractions | false |
| 23 | Here Today | - | - | - | $2,807,320 | 1,230 | $2,807,494 | May 7 | Stage 6 Films | false |
| 24 | Dream Horse | - | - | - | $2,788,135 | 1,284 | $2,913,328 | May 21 | Bleecker Street Media | false |
| 25 | Finding You | - | - | - | $2,753,585 | 1,447 | $2,753,985 | May 14 | Roadside Attractions | false |
| 26 | The House Next Door: Meet the Blacks 2 | - | - | - | $2,629,430 | 539 | $2,893,660 | Jun 11 | Hidden Empire Film Group (HEFG) | false |
| 27 | The Croods: A New Age | - | - | - | $2,471,942 | 2,211 | $58,568,815 | Nov 25 | Universal Pictures | false |
| 28 | 12 Mighty Orphans | - | - | - | $2,459,162 | 1,047 | $3,689,637 | Jun 11 | Sony Pictures Releasing | false |
| 29 | Profile | - | - | - | $1,744,740 | 2,104 | $1,744,740 | May 14 | Focus Features | false |
| 30 | Chaos Walking | - | - | - | $1,508,453 | 2,132 | $13,287,908 | Mar 5 | Lionsgate Films | false |
| 31 | Together Together | - | - | - | $1,435,671 | 665 | $1,437,938 | Apr 23 | Bleecker Street Media | false |
| 32 | Queen Bees | - | - | - | $1,406,439 | 600 | $1,926,706 | Jun 11 | Gravitas Ventures | false |
| 33 | Scott Pilgrim vs. the World 10th Anniversary (2021 Re-release) | - | - | - | $1,253,415 | 448 | $1,867,625 | - | Universal Pictures | false |
| 34 | Minari | - | - | - | $1,161,789 | 912 | $3,110,580 | Feb 12 | A24 | false |
| 35 | In the Earth | - | - | - | $1,083,576 | 571 | $1,113,723 | Apr 16 | Neon | false |
| 36 | The Father | - | - | - | $867,802 | 933 | $2,122,771 | Feb 26 | Sony Pictures Classics | false |
| 37 | Scoob! | - | - | - | $850,000 | - | $2,188,425 | May 21 | Warner Bros. | false |
| 38 | Four Good Days | - | - | - | $837,849 | 489 | $837,849 | Apr 30 | Vertical Entertainment | false |
| 39 | French Exit | - | - | - | $734,814 | 493 | $741,895 | Feb 12 | Sony Pictures Classics | false |
| 40 | The Marksman | - | - | - | $711,871 | 2,018 | $15,566,093 | Jan 15 | Open Road Films (II) | false |
| 41 | Witnesses | - | - | - | $630,018 | 90 | $855,765 | Jun 4 | Purdie Distribution | false |
| 42 | Wonder Woman 1984 | - | - | - | $588,041 | 2,218 | $46,801,036 | Dec 25 | Warner Bros. | false |
| 43 | The Sparks Brothers | - | - | - | $575,090 | 534 | $648,665 | Jun 18 | Focus Features | false |
| 44 | Zola | - | - | - | $504,992 | 1,468 | $4,844,399 | Jun 30 | A24 | false |
| 45 | Long Weekend | - | - | - | $500,652 | 821 | $1,018,532 | Mar 12 | Stage 6 Films | false |
| 46 | Promising Young Woman | - | - | - | $455,635 | 1,448 | $6,460,965 | Dec 25 | Focus Features | false |
| 47 | World War Z 2021 Re-release | - | - | - | $448,000 | 80 | $448,000 | May 28 | Paramount Pictures | false |
| 48 | 2021 Oscar Nominated Short Films: Live Action | - | - | - | $443,050 | 184 | $443,050 | Apr 2 | Magnolia Pictures | false |
| 49 | The Truffle Hunters | - | - | - | $412,301 | 105 | $521,202 | Mar 5 | Sony Pictures Classics | false |
| 50 | Top Gun 2021 Re-release | - | - | - | $408,937 | 153 | $457,577 | May 14 | Paramount Pictures | false |
| 51 | Dad, I'm Sorry | - | - | - | $350,000 | - | $350,000 | May 28 | 3388 Films | false |
| 52 | The Dry | - | - | - | $346,079 | 186 | $364,237 | May 21 | IFC Films | false |
| 53 | Werewolves Within | - | - | - | $331,914 | 270 | $575,783 | Jun 25 | IFC Films | false |
| 54 | Final Account | - | - | - | $308,976 | 308 | $308,976 | May 21 | Focus Features | false |
| 55 | The Water Man | - | - | - | $304,602 | 311 | $383,234 | May 7 | RLJE Films | false |
| 56 | New Order | - | - | - | $303,556 | 236 | $303,556 | May 21 | Neon | false |
| 57 | The Little Things | - | - | - | $300,341 | 2,206 | $15,342,746 | Jan 29 | Warner Bros. | false |
| 58 | Wrong Turn | - | - | - | $294,534 | 259 | $1,251,184 | Jan 26 | Saban Films | false |
| 59 | Boogie | - | - | - | $256,675 | 1,272 | $4,178,620 | Mar 5 | Focus Features | false |
| 60 | The War with Grandpa | - | - | - | $235,661 | 2,365 | $21,277,892 | Oct 9 | 101 Studios | false |
| 61 | Limbo | - | - | - | $224,405 | 213 | $224,405 | Apr 30 | Focus Features | false |
| 62 | Judas and the Black Messiah | - | - | - | $220,178 | 1,906 | $5,478,009 | Feb 12 | Warner Bros. | false |
| 63 | Rita Moreno: Just a Girl Who Decided to Go for It | - | - | - | $209,223 | 227 | $264,626 | Jun 18 | Roadside Attractions | false |
| 64 | The Resort | - | - | - | $191,996 | 114 | $191,996 | Apr 30 | Vertical Entertainment | false |
| 65 | Monster Hunter | - | - | - | $176,899 | 1,817 | $15,162,470 | Dec 18 | Screen Gems | false |
| 66 | Lamb of God: The Concert Film | - | - | - | $169,162 | 138 | $744,813 | Mar 12 | Excel Entertainment | false |
| 67 | Cliff Walkers | - | - | - | $152,972 | 65 | $152,972 | Apr 30 | CMC Pictures | false |
| 68 | SAS: Red Notice | - | - | - | $146,329 | 189 | $146,329 | Apr 16 | Vertical Entertainment | false |
| 69 | Shiva Baby | - | - | - | $145,047 | 27 | $159,294 | Apr 2 | Utopia | false |
| 70 | Held | - | - | - | $131,460 | 129 | $142,817 | Apr 9 | Magnolia Pictures | false |
| 71 | The Djinn | - | - | - | $124,772 | 44 | $124,772 | May 14 | IFC Films | false |
| 72 | Walking with Herb | - | - | - | $120,226 | 507 | $120,226 | May 7 | Fathom Events | false |
| 73 | The Paper Tigers | - | - | - | $108,229 | 65 | $112,691 | May 7 | Well Go USA Entertainment | false |
| 74 | The Swimming Pool 2021 Re-release | - | - | - | $98,378 | 10 | $211,467 | May 14 | Rialto Distribution | false |
| 75 | News of the World | - | - | - | $92,145 | 1,986 | $12,668,325 | Dec 25 | Universal Pictures | false |
| 76 | Mission Stories | - | - | - | $86,830 | 44 | $87,059 | May 7 | Excel Entertainment | false |
| 77 | My Love | - | - | - | $86,252 | 25 | $86,252 | May 7 | CMC Pictures | false |
| 78 | Children of the Sea | - | - | - | $81,237 | 633 | $81,237 | Mar 20 | Fathom Events | false |
| 79 | Riders of Justice | - | - | - | $71,200 | 18 | $77,115 | May 14 | Magnolia Pictures | false |
| 80 | The Killing of Two Lovers | - | - | - | $71,162 | 36 | $71,162 | May 14 | Neon | false |
| 81 | Undine | - | - | - | $69,473 | 56 | $78,689 | Jun 4 | IFC Films | false |
| 82 | Six Minutes to Midnight | - | - | - | $66,404 | 145 | $132,500 | Mar 26 | IFC Films | false |
| 83 | Gunda | - | - | - | $65,104 | 35 | $115,691 | Apr 16 | Neon | false |
| 84 | Dutch | - | - | - | $63,528 | 202 | $404,371 | Mar 12 | Faith Media Distribution | false |
| 85 | Censor | - | - | - | $61,227 | 93 | $90,050 | Jun 11 | Magnolia Pictures | false |
| 86 | City of Lies | - | - | - | $53,703 | 502 | $572,493 | Mar 19 | Saban Films | false |
| 87 | DOMINO: Battle of the Bones | - | - | - | $50,124 | - | $50,124 | Jun 11 | TriCoast Worldwide | false |
| 88 | About Endlessness | - | - | - | $43,250 | 17 | $51,386 | Apr 30 | Magnolia Pictures | false |
| 89 | Summer of 85 | - | - | - | $37,362 | 23 | $71,788 | Jun 18 | Music Box Films | false |
| 90 | All Light, Everywhere | - | - | - | $37,266 | 19 | $37,266 | Jun 4 | Super LTD | false |
| 91 | Lansky | - | - | - | $36,930 | 49 | $61,030 | Jun 25 | Vertical Entertainment | false |
| 92 | Mainstream | - | - | - | $35,696 | 76 | $35,696 | May 7 | IFC Films | false |
| 93 | The Human Factor | - | - | - | $35,570 | 90 | $36,693 | May 7 | Sony Pictures Classics | false |
| 94 | Tenet | - | - | - | $32,230 | 2,930 | $58,504,105 | Sep 3 | Warner Bros. | false |
| 95 | Monday | - | - | - | $30,932 | 54 | $30,932 | Apr 16 | IFC Films | false |
| 96 | Truman & Tennessee: An Intimate Conversation | - | - | - | $30,511 | 22 | $54,817 | Jun 18 | Kino Lorber | false |
| 97 | Trigger Point | - | - | - | $29,262 | 77 | $29,262 | Apr 16 | Screen Media Films | false |
| 98 | The Perfect Candidate | - | - | - | $28,466 | 17 | $30,134 | May 14 | Music Box Films | false |
| 99 | Holler | - | - | - | $27,793 | 31 | $28,706 | Jun 11 | IFC Films | false |
| 100 | Jakob's Wife | - | - | - | $27,588 | 101 | $27,588 | Apr 16 | - | false |
| 101 | Moffie | - | - | - | $24,520 | 51 | $24,520 | Apr 9 | IFC Films | false |
| 102 | Our Ladies | - | - | - | $24,360 | 25 | $27,558 | Jun 18 | Sony Pictures Releasing | false |
| 103 | 100% Wolf | - | - | - | $22,820 | 124 | $658,764 | Oct 9 | Viva Pictures | false |
| 104 | Gully | - | - | - | $22,517 | 100 | $22,517 | Jun 4 | Vertical Entertainment | false |
| 105 | Hero Mode | - | - | - | $21,178 | 46 | $21,178 | Jun 4 | Blue Fox Entertainment | false |
| 106 | I Carry You with Me | - | - | - | $20,184 | 111 | $166,403 | Jun 25 | Sony Pictures Classics | false |
| 107 | Gaia | - | - | - | $17,530 | 75 | $17,530 | Jun 18 | Neon | false |
| 108 | Equal Standard | - | - | - | $15,938 | 25 | $15,938 | May 7 | Mutiny Pictures | false |
| 109 | We Broke Up | - | - | - | $15,063 | 35 | $15,063 | Apr 16 | Vertical Entertainment | false |
| 110 | Counter Column | - | - | - | $14,864 | 7 | $32,323 | Oct 16 | Not That Kind of Movie Productions | false |
| 111 | The Red Circle 2021 Re-release | - | - | - | $14,772 | 5 | $62,850 | Jun 25 | Rialto Pictures | false |
| 112 | American Traitor: The Trial of Axis Sally | - | - | - | $14,000 | - | $14,000 | May 28 | Vertical Entertainment | false |
| 113 | The Ladykillers 2021 Re-release | - | - | - | $12,772 | 3 | $23,213 | Jun 4 | Rialto Pictures | false |
| 114 | A Soldier's Story 2: Return from the Dead | - | - | - | $11,190 | 5 | $21,543 | Jun 26 | Indican Pictures | false |
| 115 | State Funeral | - | - | - | $9,913 | 2 | $11,342 | May 7 | MUBI | false |
| 116 | Senior Moment | - | - | - | $9,913 | 57 | $41,598 | Mar 26 | Screen Media Films | false |
| 117 | There Is No Evil | - | - | - | $8,063 | 7 | $8,063 | May 14 | Kino Lorber | false |
| 118 | Endless Rain | - | - | - | $7,334 | 14 | $7,334 | Apr 30 | Sony Pictures Releasing | false |
| 119 | Final Frequency | - | - | - | $7,098 | 9 | $7,098 | Jun 11 | Integrity Releasing | false |
| 120 | Ghost Master | - | - | - | $6,130 | 2 | $6,136 | May 14 | Indican Pictures | false |
| 121 | The Boonies | - | - | - | $6,091 | 2 | $6,887 | Mar 31 | Indican Pictures | false |
| 122 | Blood Brothers: Civil War | - | - | - | $5,191 | 2 | $5,191 | Apr 2 | Indican Pictures | false |
| 123 | Blithe Spirit | - | - | - | $5,113 | 239 | $282,500 | Feb 19 | IFC Films | false |
| 124 | Bill Traylor: Chasing Ghosts | - | - | - | $4,504 | 2 | $4,504 | Apr 16 | Kino Lorber | false |
| 125 | Sweat | - | - | - | $3,406 | 6 | $11,546 | Jun 18 | MUBI | false |
| 126 | A Writer's Odyssey | - | - | - | $3,240 | 117 | $160,013 | Feb 12 | CMC Pictures | false |
| 127 | Paper Spiders | - | - | - | $2,992 | 17 | $2,992 | May 7 | Entertainment Squad | false |
| 128 | Slalom | - | - | - | $2,796 | 4 | $2,788 | Apr 9 | Kino Lorber | false |
| 129 | Psycho Goreman | - | - | - | $2,402 | 70 | $95,182 | Jan 22 | RLJE Films | false |
| 130 | Mystery of the Kingdom of God | - | - | - | $2,174 | 106 | $17,316 | Mar 26 | Atlas Distribution Company | false |
| 131 | Crack House of the Dead | - | - | - | $1,616 | 5 | $1,616 | Jun 18 | Sunrayz International Films | false |
| 132 | Things Don't Stay Fixed | - | - | - | $1,610 | 3 | $5,430 | Mar 26 | Indican Pictures | false |
| 133 | Bang! Bang! | - | - | - | $1,348 | 1 | $6,390 | Oct 23 | Indican Pictures | false |
| 134 | Last Call | - | - | - | $1,313 | 110 | $48,144 | Mar 19 | IFC Films | false |
| 135 | The Incredible 25th Year of Mitzi Bearclaw | - | - | - | $1,299 | 2 | $10,368 | Feb 12 | Indican Pictures | false |
| 136 | My Zoe | - | - | - | $1,133 | 237 | $52,733 | Feb 26 | Blue Fox Entertainment | false |
| 137 | The Unthinkable | - | - | - | $974 | 3 | $974 | May 7 | Magnolia Pictures | false |
| 138 | The Mauritanian | - | - | - | $812 | 287 | $836,536 | Feb 12 | STX Entertainment | false |
| 139 | Come True | - | - | - | $600 | 96 | $62,080 | Mar 12 | IFC Films | false |
| 140 | Safer at Home | - | - | - | $516 | 79 | $95,643 | Feb 26 | Vertical Entertainment | false |
| 141 | Funhouse | - | - | - | $507 | 3 | $507 | May 28 | Magnet Releasing | false |
| 142 | Supernova | - | - | - | $464 | 330 | $234,220 | Jan 29 | Bleecker Street Media | false |
| 143 | The Evil Next Door | - | - | - | $462 | 3 | $1,010 | Jun 25 | Magnolia Pictures | false |
| 144 | The World to Come | - | - | - | $449 | 277 | $116,143 | Feb 12 | Bleecker Street Media | false |
| 145 | No Place | - | - | - | $363 | 1 | $4,194 | Mar 5 | Indican Pictures | false |
| 146 | The Vigil | - | - | - | $332 | 55 | $50,439 | Feb 26 | IFC Films | false |
| 147 | First Signal | - | - | - | $300 | 1 | $880 | Mar 26 | The Ashton Times | false |
| 148 | Stray | - | - | - | $271 | 17 | $13,325 | Mar 5 | Magnolia Pictures | false |
| 149 | My Salinger Year | - | - | - | $270 | 123 | $54,730 | Mar 5 | IFC Films | false |
| 150 | Felix and the Hidden Treasure | - | - | - | $126 | 10 | $153 | Jun 25 | Viva Pictures | false |
| 151 | The Shade Shepherd | - | - | - | $120 | 1 | $4,409 | Oct 16 | Indican Pictures | false |
| 152 | Abandoned: Angelique's Isle | - | - | - | $100 | 1 | $6,055 | Feb 19 | Indican Pictures | false |
