| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Top Gun: Maverick | - | - | - | $239,649,177 | 4,751 | $718,732,821 | 33.3% | May 27, 2022 | Paramount Pictures |
| 2 | Jurassic World: Dominion | - | - | - | $182,471,110 | 4,697 | $376,851,080 | 48.4% | Jun 10, 2022 | Universal Pictures |
| 3 | Doctor Strange in the Multiverse of Madness | - | - | - | $23,737,194 | 4,534 | $411,331,607 | 5.8% | May 6, 2022 | Walt Disney Studios Motion Pictures |
| 4 | The Bob's Burgers Movie | - | - | - | $12,394,426 | 3,425 | $31,933,830 | 38.8% | May 27, 2022 | 20th Century Studios |
| 5 | Downton Abbey: A New Era | - | - | - | $10,122,920 | 3,830 | $44,141,550 | 22.9% | May 20, 2022 | Focus Features |
| 6 | The Bad Guys | - | - | - | $10,050,475 | 4,042 | $97,459,240 | 10.3% | Apr 22, 2022 | Universal Pictures |
| 7 | Everything Everywhere All at Once | - | - | - | $5,559,024 | 2,220 | $77,191,785 | 7.2% | Mar 25, 2022 | A24 |
| 8 | Sonic the Hedgehog 2 | - | - | - | $4,159,302 | 4,258 | $190,872,904 | 2.2% | Apr 8, 2022 | Paramount Pictures |
| 9 | The Lost City | - | - | - | $2,660,975 | 4,283 | $105,344,029 | 2.5% | Mar 25, 2022 | Paramount Pictures |
| 10 | Crimes of the Future | - | - | - | $2,216,314 | 773 | $2,452,882 | 90.4% | Jun 3, 2022 | Neon |
| 11 | Vikram | - | - | - | $1,770,000 | 465 | $1,770,000 | 100% | Jun 3, 2022 | Prime Media Pictures |
| 12 | Watcher | - | - | - | $1,746,396 | 764 | $1,961,207 | 89% | Jun 3, 2022 | IFC Films |
| 13 | Firestarter | - | - | - | $1,131,445 | 3,413 | $9,739,250 | 11.6% | May 13, 2022 | Universal Pictures |
| 14 | Men | - | - | - | $915,103 | 2,212 | $7,587,853 | 12.1% | May 20, 2022 | A24 |
| 15 | Fantastic Beasts: The Secrets of Dumbledore | - | - | - | $760,280 | 4,245 | $95,850,844 | 0.8% | Apr 15, 2022 | Warner Bros. |
| 16 | Ante Sundharaniki | - | - | - | $621,000 | 350 | $620,000 | 100.2% | Jun 10, 2022 | N/A |
| 17 | Morbius | - | - | - | $543,176 | 4,268 | $73,865,530 | 0.7% | Apr 1, 2022 | Columbia Pictures |
| 18 | Uncharted | - | - | - | $522,889 | 4,275 | $148,648,820 | 0.4% | Feb 18, 2022 | Sony Pictures Releasing |
| 19 | Family Camp | - | - | - | $403,832 | 1,057 | $3,973,263 | 10.2% | May 13, 2022 | Roadside Attractions |
| 20 | The Roundup | - | - | - | $343,186 | 22 | $812,859 | 42.2% | May 19, 2022 | Capelight Pictures |
| 21 | The Northman | - | - | - | $338,025 | 3,284 | $34,233,110 | 1% | Apr 22, 2022 | Focus Features |
| 22 | Deep in the Heart: A Texas Wildlife Story | - | - | - | $309,090 | 69 | $480,240 | 64.4% | Jun 3, 2022 | Fin & Fur Films |
| 23 | The Unbearable Weight of Massive Talent | - | - | - | $208,156 | 3,036 | $20,300,157 | 1% | Apr 22, 2022 | Lionsgate |
| 24 | Eiffel | - | - | - | $203,729 | 308 | $444,814 | 45.8% | Apr 29, 2022 | Blue Fox Entertainment |
| 25 | Benediction | - | - | - | $154,555 | 1,241 | $201,093 | 76.9% | Jun 3, 2022 | Roadside Attractions |
| 26 | 2000 Mules | - | - | - | $154,065 | 415 | $1,465,513 | 10.5% | May 20, 2022 | D'Souza Media |
| 27 | The Duke | - | - | - | $121,290 | 353 | $1,526,970 | 7.9% | Apr 22, 2022 | Sony Pictures Classics |
| 28 | Jazz Fest: A New Orleans Story | - | - | - | $121,125 | 302 | $179,005 | 67.7% | May 13, 2022 | Sony Pictures Releasing |
| 29 | Father Stu | - | - | - | $117,552 | 2,705 | $20,884,796 | 0.6% | Apr 13, 2022 | Sony Pictures Releasing |
| 30 | Fortune Favors Lady Nikuko | - | - | - | $90,880 | 476 | $91,653 | 99.2% | Jun 2, 2022 | GKIDS |
| 31 | Montana Story | - | - | - | $81,412 | 290 | $292,915 | 27.8% | May 13, 2022 | Bleecker Street Media |
| 32 | RRR 2022 Re-release | - | - | - | $80,734 | 135 | $399,485 | 20.2% | Jun 1, 2022 | Variance Films |
| 33 | The Phantom of the Open | - | - | - | $66,178 | 501 | $748,695 | 8.8% | Jun 3, 2022 | Sony Pictures Classics |
| 34 | Petite Maman | - | - | - | $56,944 | 224 | $829,065 | 6.9% | Apr 22, 2022 | Neon |
| 35 | ¿Y cómo es él? | - | - | - | $46,683 | 325 | $1,500,636 | 3.1% | Apr 22, 2022 | Lionsgate |
| 36 | Maika | - | - | - | $46,421 | 23 | $69,257 | 67% | Jun 3, 2022 | Well Go USA Entertainment |
| 37 | Neptune Frost | - | - | - | $43,007 | 42 | $193,875 | 22.2% | Jun 3, 2022 | Kino Lorber |
| 38 | A Chiara | - | - | - | $29,644 | 28 | $41,925 | 70.7% | May 27, 2022 | Neon |
| 39 | Lost Illusions | - | - | - | $21,516 | 17 | $126,391 | 17% | Jun 10, 2022 | Music Box Films |
| 40 | Freakscene: The Story of Dinosaur Jr. | - | - | - | $20,591 | 69 | $67,979 | 30.3% | May 27, 2022 | Utopia |
| 41 | Spider-Man: No Way Home | - | - | - | $19,169 | 4,336 | $804,793,477 | <0.1% | Dec 17, 2021 | Sony Pictures Releasing |
| 42 | Poser | - | - | - | $17,464 | 9 | $42,179 | 41.4% | Jun 3, 2022 | Oscilloscope |
| 43 | Hit the Road | - | - | - | $17,138 | 432 | $151,018 | 11.3% | Apr 22, 2022 | Kino Lorber |
| 44 | Fireheart | - | - | - | $13,524 | 22 | $49,848 | 27.1% | May 27, 2022 | Entertainment One |
| 45 | Mad God | - | - | - | $13,038 | 37 | $325,042 | 4% | Jun 10, 2022 | IFC Films |
| 46 | Back to the Drive-in | - | - | - | $12,318 | 17 | $626,557 | 2% | Jun 6, 2022 | - |
| 47 | Love in Kilnerry | - | - | - | $11,140 | 11 | $213,099 | 5.2% | Apr 8, 2022 | Archway Pictures |
| 48 | The Velvet Queen | - | - | - | $10,757 | 51 | $151,006 | 7.1% | Dec 22, 2021 | Oscilloscope |
| 49 | The Batman | - | - | - | $10,391 | 4,417 | $369,345,583 | <0.1% | Mar 4, 2022 | Warner Bros. |
| 50 | The Automat | - | - | - | $10,080 | 20 | $257,371 | 3.9% | Feb 18, 2022 | Slice of Pie |
| 51 | Relative | - | - | - | $7,776 | 1 | $21,257 | 36.6% | Jun 8, 2022 | Newcity |
| 52 | Pleasure | - | - | - | $7,403 | 44 | $106,789 | 6.9% | May 13, 2022 | Neon |
| 53 | Happening | - | - | - | $7,318 | 188 | $181,023 | 4% | May 6, 2022 | IFC Films |
| 54 | Diva 2022 Re-release | - | - | - | $6,722 | 2 | $73,411 | 9.2% | May 6, 2022 | Rialto Pictures |
| 55 | Rite of the Shaman | - | - | - | $6,688 | 12 | $16,210 | 41.3% | May 27, 2022 | Purdie Distribution |
| 56 | 1982 | - | - | - | $6,015 | 5 | $43,829 | 13.7% | Jun 10, 2022 | Tricycle Logic |
| 57 | Green Ghost and the Masters of the Stone | - | - | - | $4,369 | 135 | $113,685 | 3.8% | Apr 29, 2022 | Gravitas Ventures |
| 58 | Lux Æterna | - | - | - | $4,116 | 25 | $50,027 | 8.2% | May 6, 2022 | Yellow Veil Pictures |
| 59 | Vortex | - | - | - | $3,914 | 39 | $145,708 | 2.7% | May 6, 2022 | Utopia |
| 60 | Take Me to the River: New Orleans | - | - | - | $3,350 | 33 | $43,563 | 7.7% | Apr 22, 2022 | N/A |
| 61 | Distant 2022 Re-release | - | - | - | $2,301 | 4 | $10,329 | 22.3% | May 20, 2022 | Big World Pictures |
| 62 | Firebird | - | - | - | $2,056 | 89 | $144,118 | 1.4% | Apr 29, 2022 | Roadside Attractions |
| 63 | Kill Devil Hills | - | - | - | $2,022 | 1 | $2,022 | 100% | Jun 4, 2022 | Sumbadhat Productions |
| 64 | Fire in the Mountains | - | - | - | $2,013 | 5 | $12,038 | 16.7% | May 20, 2022 | Kino Lorber |
| 65 | The Rose Maker | - | - | - | $1,837 | 26 | $119,160 | 1.5% | Apr 1, 2022 | Music Box Films |
| 66 | Remembering Heaven | - | - | - | $1,424 | 14 | $40,907 | 3.5% | May 6, 2022 | Purdie Distribution |
| 67 | Kamikaze Hearts | - | - | - | $1,156 | 3 | $6,669 | 17.3% | May 13, 2022 | N/A |
| 68 | The Conversation 2022 Re-release | - | - | - | $995 | 19 | $143,329 | 0.7% | May 6, 2022 | Rialto Pictures |
| 69 | We're All Going to the World's Fair | - | - | - | $928 | 9 | $101,178 | 0.9% | Apr 15, 2022 | Utopia |
| 70 | Paap Punyo | - | - | - | $892 | 91 | $26,037 | 3.4% | May 20, 2022 | Swapna Scarecrow |
| 71 | Be Natural: The Untold Story of Alice Guy-Blaché 2022 Re-release | - | - | - | $780 | - | $780 | 100% | Jun 2, 2022 | - |
| 72 | The Wobblies 2022 Re-release | - | - | - | $582 | 13 | $12,232 | 4.8% | Apr 29, 2022 | Kino Lorber |
| 73 | Aline | - | - | - | $581 | 72 | $667,815 | <0.1% | Nov 26, 2021 | Roadside Attractions |
| 74 | Mondocane | - | - | - | $472 | 5 | $4,927 | 9.6% | May 20, 2022 | Kino Lorber |
| 75 | Around the World in 80 Days | - | - | - | $117 | 86 | $48,757 | 0.2% | May 12, 2022 | Viva Pictures |
| 76 | Bronco Bullfrog 2022 Re-release | - | - | - | $106 | 2 | $13,171 | 0.8% | Mar 25, 2022 | Seventy-Seven |
