| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Cars | - | - | - | $1,957,375 | 127 | $3,100,679 | 63.1% | Jun 29, 2006 | Buena Vista International |
| 2 | Bañeros III, todopoderosos | - | - | - | $678,554 | 105 | $3,018,987 | 22.5% | Jul 13, 2006 | Argentina Sono Film S.A.C.I. |
| 3 | El ratón Pérez | - | - | - | $573,680 | 110 | $2,390,912 | 24% | Jul 6, 2006 | Buena Vista International |
| 4 | Patoruzito: The Great Adventure | - | - | - | $567,088 | 141 | $1,427,293 | 39.7% | Jun 29, 2006 | Warner Bros. |
| 5 | Poseidon | - | - | - | $530,558 | 76 | $1,414,063 | 37.5% | Jun 15, 2006 | Warner Bros. |
| 6 | Over the Hedge | - | - | - | $519,931 | 145 | $2,652,731 | 19.6% | Jul 13, 2006 | United International Pictures |
| 7 | Superman Returns | - | - | - | $471,741 | 132 | $1,560,704 | 30.2% | Jul 13, 2006 | Warner Bros. |
| 8 | Garfield: A Tail of Two Kitties | - | - | - | $376,856 | 77 | $844,279 | 44.6% | Jul 6, 2006 | 20th Century Fox International |
| 9 | Prime | - | - | - | $286,620 | 28 | $1,310,973 | 21.9% | May 25, 2006 | Distribution Company |
| 10 | The Omen | - | - | - | $220,613 | 52 | $1,040,082 | 21.2% | Jun 8, 2006 | 20th Century Fox International |
| 11 | X-Men: The Last Stand | - | - | - | $185,444 | 102 | $2,202,510 | 8.4% | May 25, 2006 | 20th Century Fox International |
| 12 | The Da Vinci Code | - | - | - | $152,665 | 124 | $4,748,930 | 3.2% | May 18, 2006 | Sony Pictures Releasing |
| 13 | The Beat That My Heart Skipped 2005 Re-release | - | - | - | $92,280 | 15 | $257,104 | 35.9% | Jun 15, 2006 | Alfa Films |
| 14 | Live and Become | - | - | - | $86,900 | 6 | $256,234 | 33.9% | Jun 15, 2006 | Distribution Company |
| 15 | Reeker | - | - | - | $86,467 | 21 | $185,793 | 46.5% | Jun 15, 2006 | Eurocine |
| 16 | Lord of War | - | - | - | $86,328 | 33 | $419,282 | 20.6% | Jun 1, 2006 | Alfa Films |
| 17 | Sunday Lunch 2006 Re-release | - | - | - | $67,365 | 9 | $113,052 | 59.6% | Jun 29, 2006 | CDI Films |
| 18 | Paradise Now | - | - | - | $63,701 | 11 | $128,803 | 49.5% | Jun 22, 2006 | Alfa Films |
| 19 | The Libertine | - | - | - | $53,048 | 18 | $153,513 | 34.6% | Jun 22, 2006 | Distribution Company |
| 20 | Private | - | - | - | $38,372 | 8 | $68,798 | 55.8% | Jul 6, 2006 | Distribution Company |
| 21 | Eight Below | - | - | - | $18,824 | 35 | $346,174 | 5.4% | May 25, 2006 | Buena Vista International |
| 22 | Tarnation 2006 Re-release | - | - | - | $16,715 | 2 | $22,554 | 74.1% | Jul 6, 2006 | 791 Cine |
| 23 | The Shaggy Dog | - | - | - | $13,224 | 26 | $398,171 | 3.3% | Apr 20, 2006 | Buena Vista International |
| 24 | Dreamer | - | - | - | $11,392 | 16 | $95,086 | 12% | Jun 8, 2006 | Distribution Company |
| 25 | Triple Agent 2006 Re-release | - | - | - | $9,260 | 3 | $9,260 | 100% | Jun 29, 2006 | CDI Films |
| 26 | March of the Penguins | - | - | - | $5,102 | 39 | $445,938 | 1.1% | May 11, 2006 | Alfa Films |
| 27 | Mission: Impossible III | - | - | - | $4,561 | 123 | $1,585,642 | 0.3% | May 4, 2006 | United International Pictures |
