| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Tenet | - | - | - | $4,835,162 | 874 | $8,034,640 | Aug 26 | Warner Bros. | false |
| 2 | After We Collided | - | - | - | $4,017,679 | 743 | $4,842,527 | Sep 2 | 01 Distribution | false |
| 3 | The New Mutants | - | - | - | $623,508 | 351 | $732,337 | Sep 2 | Walt Disney Pictures | false |
| 4 | Unhinged | - | - | - | $621,600 | 415 | $1,490,260 | Sep 24 | 01 Distribution | false |
| 5 | Onward | - | - | - | $567,755 | 512 | $1,469,373 | Aug 19 | Walt Disney Pictures | false |
| 6 | Padrenostro | - | - | - | $544,980 | 457 | $1,160,718 | Sep 24 | - | false |
| 7 | Break the Silence: The Movie | - | - | - | $452,337 | 230 | $452,337 | Sep 10 | Nexo Digital | false |
| 8 | Endless | - | - | - | $404,508 | 406 | $736,813 | Sep 23 | Eagle Pictures | false |
| 9 | Thou Shalt Not Hate | - | - | - | $401,021 | 262 | $425,244 | Sep 10 | Notorious Pictures | false |
| 10 | The Macaluso Sisters | - | - | - | $374,042 | 123 | $528,744 | Sep 10 | Teodora Film | false |
| 11 | Miss Marx | - | - | - | $345,885 | 222 | $526,786 | Sep 17 | 01 Distribution | false |
| 12 | Waiting for the Barbarians | - | - | - | $327,567 | 108 | $614,247 | Sep 24 | Iervolino Entertainment | false |
| 13 | The Best Is Yet to Come | - | - | - | $306,096 | 331 | $477,044 | Aug 21 | Lucky Red | false |
| 14 | The Jack in the Box | - | - | - | $294,673 | 207 | $340,145 | Sep 17 | Adler Entertainment | false |
| 15 | Hidden Away | - | - | - | $252,983 | 316 | $1,031,096 | Mar 4 | 01 Distribution | false |
| 16 | Missing Link | - | - | - | $200,861 | 289 | $316,241 | Sep 17 | 01 Distribution | false |
| 17 | The Vigil | - | - | - | $191,486 | 170 | $191,486 | Sep 10 | BIM Distribuzione | false |
| 18 | Yesterday | - | - | - | $168,405 | 369 | $1,082,927 | Sep 26 | Universal Pictures International (UPI) | false |
| 19 | Dreambuilders | - | - | - | $149,796 | 210 | $222,657 | Sep 10 | BIM Distribuzione | false |
| 20 | Dogtooth 2020 Re-release | - | - | - | $141,861 | 136 | $256,031 | Aug 27 | Lucky Red | false |
| 21 | The Great Alaskan Race | - | - | - | $136,021 | 201 | $229,350 | Sep 3 | Notorious Pictures | false |
| 22 | A Good Doctor | - | - | - | $122,225 | 221 | $122,225 | Sep 10 | Medusa Distribuzione | false |
| 23 | Notturno | - | - | - | $90,346 | 92 | $95,824 | Sep 9 | 01 Distribution | false |
| 24 | Gretel & Hansel | - | - | - | $84,430 | 227 | $374,190 | Aug 20 | Koch Media | false |
| 25 | Assandira | - | - | - | $49,764 | 24 | $53,378 | Sep 9 | Lucky Red | false |
| 26 | Romantic Guide to Lost Places | - | - | - | $48,951 | 180 | $48,951 | Sep 24 | Lucky Red | false |
| 27 | Crescendo | - | - | - | $47,686 | 38 | $97,861 | Aug 27 | Satine Film | false |
| 28 | Molecole | - | - | - | $44,471 | 40 | $46,252 | Sep 3 | Zalab Film | false |
| 29 | Undine | - | - | - | $42,427 | 51 | $145,702 | Sep 24 | Europictures | false |
| 30 | The Perfect Candidate | - | - | - | $41,720 | 41 | $73,346 | Sep 3 | - | false |
| 31 | Papicha | - | - | - | $35,975 | 27 | $96,396 | Jul 3 | Teodora Film | false |
| 32 | Ema | - | - | - | $12,941 | 31 | $23,290 | Sep 3 | Movies Inspired | false |
| 33 | Sow the Wind | - | - | - | $10,250 | 21 | $15,460 | Sep 3 | I Wonder Pictures | false |
| 34 | The Big Step | - | - | - | $9,833 | 47 | $83,298 | Aug 20 | Tucker Film | false |
| 35 | Gauguin a Tahiti. Il paradiso perduto | - | - | - | $8,553 | 35 | $8,553 | Sep 17 | Draka Distribution | false |
| 36 | Whatever Happened to My Revolution | - | - | - | $7,978 | 18 | $37,535 | Aug 27 | Wanted | false |
| 37 | La piazza della mia città - Bologna e Lo Stato Sociale | - | - | - | $6,103 | 2 | $6,230 | Sep 10 | I Wonder Pictures | false |
| 38 | La vacanza | - | - | - | $5,513 | 45 | $7,494 | Sep 3 | Adler Entertainment | false |
| 39 | A Rainy Day in New York | - | - | - | $4,890 | 431 | $3,832,707 | Nov 28 | Lucky Red | false |
| 40 | Les Misérables | - | - | - | $4,729 | 42 | $191,646 | Jun 18 | Lucky Red | false |
| 41 | The Shiny Shrimps | - | - | - | $3,810 | 15 | $47,351 | Jul 9 | Movies Inspired | false |
| 42 | Emma. | - | - | - | $2,792 | 10 | $37,602 | Jun 16 | Universal Pictures International (UPI) | false |
| 43 | Downton Abbey | - | - | - | $1,952 | 374 | $3,515,607 | Oct 24 | Universal Pictures International (UPI) | false |
| 44 | Trolls World Tour | - | - | - | $1,345 | 21 | $58,741 | Jun 15 | Universal Pictures International (UPI) | false |
| 45 | 1917 | - | - | - | $1,061 | 565 | $7,339,129 | Jan 23 | 01 Distribution | false |
| 46 | Knives Out | - | - | - | $666 | 468 | $5,661,031 | Dec 5 | 01 Distribution | false |
| 47 | Dark Waters | - | - | - | $523 | 245 | $536,894 | Feb 20 | Eagle Pictures | false |
| 48 | Abominable | - | - | - | $429 | 438 | $2,486,480 | Oct 3 | Universal Pictures International (UPI) | false |
| 49 | The Invisible Man | - | - | - | $373 | 8 | $15,853 | Jun 15 | Universal Pictures International (UPI) | false |
| 50 | The Addams Family | - | - | - | $345 | 555 | $7,192,896 | Oct 31 | Eagle Pictures | false |
| 51 | Cats | - | - | - | $77 | 101 | $31,103 | Feb 20 | Universal Pictures International (UPI) | false |
| 52 | Champions | - | - | - | $64 | 123 | $355,079 | - | BIM Distribuzione | false |
