| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Toy Story 3 | - | - | - | $9,777,241 | 569 | $116,625,632 | Jul 23 | Walt Disney Pictures | false |
| 2 | Grown Ups | - | - | - | $8,070,902 | 401 | $12,161,427 | Aug 27 | Sony Pictures Releasing | false |
| 3 | The Other Guys | - | - | - | $7,998,154 | 444 | $12,605,131 | Sep 17 | Sony Pictures Releasing | false |
| 4 | Resident Evil: Afterlife | - | - | - | $6,529,852 | 361 | $7,492,098 | Sep 10 | Sony Pictures Releasing | false |
| 5 | The Last Exorcism | - | - | - | $5,552,740 | 322 | $5,874,380 | Sep 3 | Optimum Releasing | false |
| 6 | Scott Pilgrim vs. the World | - | - | - | $5,551,380 | 414 | $8,445,713 | Aug 27 | Universal Pictures International (UPI) | false |
| 7 | The Expendables | - | - | - | $4,470,085 | 453 | $15,969,695 | Aug 20 | Lionsgate | false |
| 8 | Inception | - | - | - | $4,430,067 | 472 | $56,566,947 | Jul 16 | Warner Bros. | false |
| 9 | Salt | - | - | - | $3,725,964 | 413 | $11,321,253 | Aug 20 | Sony Pictures Releasing | false |
| 10 | Devil | - | - | - | $3,410,805 | 338 | $4,477,471 | Sep 17 | Universal Pictures International (UPI) | false |
| 11 | Tamara Drewe | - | - | - | $3,330,735 | 358 | $4,013,954 | Sep 10 | Momentum Pictures | false |
| 12 | Eat Pray Love | - | - | - | $3,268,076 | 433 | $7,371,485 | Sep 24 | Sony Pictures Releasing | false |
| 13 | Marmaduke | - | - | - | $3,085,433 | 457 | $9,019,305 | Aug 20 | 20th Century Fox International | false |
| 14 | Dinner for Schmucks | - | - | - | $2,869,848 | 428 | $4,040,902 | Sep 3 | Paramount Pictures International | false |
| 15 | The Town | - | - | - | $2,724,131 | 326 | $7,484,217 | Sep 24 | Warner Bros. | false |
| 16 | Diary of a Wimpy Kid | - | - | - | $2,618,057 | 372 | $4,283,601 | Aug 27 | 20th Century Fox International | false |
| 17 | The Hole | - | - | - | $1,868,193 | 362 | $4,499,067 | Sep 24 | - | false |
| 18 | Piranha 3D | - | - | - | $1,796,460 | 354 | $6,903,929 | Aug 20 | Entertainment Film Distributors | false |
| 19 | Going the Distance | - | - | - | $1,609,658 | 360 | $2,124,322 | Sep 10 | Warner Bros. | false |
| 20 | Cyrus | - | - | - | $1,436,638 | 261 | $1,936,218 | Sep 10 | 20th Century Fox International | false |
| 21 | The Switch | - | - | - | $1,029,490 | 357 | $1,029,490 | Sep 3 | Lionsgate | false |
| 22 | The Girl Who Played with Fire | - | - | - | $770,521 | 141 | $2,556,558 | Aug 27 | Momentum Pictures | false |
| 23 | Winter's Bone | - | - | - | $568,245 | 72 | $947,359 | Sep 17 | Artificial Eye | false |
| 24 | Dabangg | - | - | - | $511,309 | 41 | $1,247,468 | Sep 10 | Eros Worldwide | false |
| 25 | Avatar | - | - | - | $259,913 | 503 | $147,646,580 | Dec 18 | 20th Century Fox International | false |
| 26 | We Are Family | - | - | - | $251,744 | 51 | $251,744 | Sep 3 | UTV Motion Pictures | false |
