| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Resident Evil: Afterlife | - | - | - | $1,583,810 | 57 | $2,427,531 | Sep 16 | Constantin Film | false |
| 2 | Step Up 3D | - | - | - | $1,351,600 | 49 | $2,349,174 | Aug 26 | Constantin Film | false |
| 3 | Vampires Suck | - | - | - | $1,193,543 | 80 | $1,299,458 | Sep 10 | 20th Century Fox International | false |
| 4 | The Sorcerer's Apprentice | - | - | - | $1,002,953 | 71 | $1,187,281 | Sep 2 | Walt Disney Pictures | false |
| 5 | Get Him to the Greek | - | - | - | $885,859 | 43 | $1,011,591 | Sep 3 | Universal Pictures International (UPI) | false |
| 6 | The Expendables | - | - | - | $762,280 | 72 | $1,656,368 | Aug 27 | 20th Century Fox International | false |
| 7 | Eat Pray Love | - | - | - | $607,070 | 90 | $2,000,100 | Sep 24 | Sony Pictures Releasing | false |
| 8 | The Last Airbender | - | - | - | $594,716 | 82 | $2,191,663 | Aug 20 | Universal Pictures International (UPI) | false |
| 9 | Inception | - | - | - | $515,673 | 72 | $3,607,185 | Jul 29 | Warner Bros. | false |
| 10 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $371,863 | 65 | $1,162,088 | Aug 13 | Warner Bros. | false |
| 11 | Der Atem des Himmels | - | - | - | $355,516 | 38 | $620,346 | Sep 3 | Constantin Film | false |
| 12 | Toy Story 3 | - | - | - | $344,159 | 99 | $2,265,419 | Jul 29 | Walt Disney Pictures | false |
| 13 | In the Beginning There Was Light | - | - | - | $336,643 | 54 | $960,029 | Sep 17 | - | false |
| 14 | Going the Distance | - | - | - | $322,000 | 48 | $349,423 | Sep 3 | Warner Bros. | false |
| 15 | The American | - | - | - | $306,329 | 25 | $466,414 | Sep 17 | Constantin Film | false |
| 16 | Grown Ups | - | - | - | $270,725 | 88 | $3,521,030 | Aug 6 | Sony Pictures Releasing | false |
| 17 | Salt | - | - | - | $253,942 | 83 | $1,159,422 | Aug 20 | Sony Pictures Releasing | false |
| 18 | Letters to Juliet | - | - | - | $192,065 | 35 | $604,251 | Aug 19 | Constantin Film | false |
| 19 | Dinner for Schmucks | - | - | - | $187,642 | 44 | $370,361 | Sep 24 | Universal Pictures International (UPI) | false |
| 20 | Loose Cannons | - | - | - | $164,211 | 22 | $456,719 | Aug 6 | Polyfilm Verleih | false |
| 21 | The Concert | - | - | - | $150,363 | 27 | $460,521 | Aug 13 | Filmladen | false |
| 22 | Marmaduke | - | - | - | $135,151 | 66 | $1,297,402 | Jul 16 | 20th Century Fox International | false |
| 23 | The Town | - | - | - | $125,538 | 26 | $291,641 | Sep 23 | Warner Bros. | false |
| 24 | Single by Contract | - | - | - | $121,674 | 45 | $185,597 | Sep 16 | Walt Disney Pictures | false |
| 25 | Mahler on the Couch | - | - | - | $107,200 | 17 | $173,233 | Sep 9 | - | false |
| 26 | Hanni & Nanni | - | - | - | $98,761 | 48 | $854,586 | Jun 18 | Universal Pictures International (UPI) | false |
| 27 | Little Nicholas | - | - | - | $93,207 | 36 | $173,024 | Sep 17 | Filmladen | false |
| 28 | Killers | - | - | - | $89,082 | 48 | $860,858 | Aug 5 | - | false |
| 29 | Babies | - | - | - | $84,220 | 21 | $196,109 | Aug 19 | - | false |
| 30 | Jew Suss: Rise and Fall | - | - | - | $77,906 | 32 | $179,272 | Sep 24 | - | false |
| 31 | Mary and Max | - | - | - | $67,165 | 14 | $126,470 | Aug 27 | Polyfilm Verleih | false |
| 32 | Easy Virtue | - | - | - | $58,018 | 29 | $71,769 | Sep 10 | Sony Pictures Releasing | false |
| 33 | Gypsy Spirit: Harri Stojka - Eine Reise | - | - | - | $56,069 | 9 | $80,396 | Sep 3 | - | false |
| 34 | Furcht & Zittern | - | - | - | $52,758 | 48 | $59,785 | Sep 9 | - | false |
| 35 | Women Without Men | - | - | - | $43,257 | 6 | $74,283 | Sep 10 | Polyfilm Verleih | false |
| 36 | Life Is Too Long | - | - | - | $39,825 | 15 | $41,641 | Sep 3 | Filmladen | false |
| 37 | The Karate Kid | - | - | - | $28,999 | 66 | $1,632,594 | Jul 23 | Sony Pictures Releasing | false |
| 38 | Honey | - | - | - | $25,988 | 2 | $56,744 | Sep 3 | Stadtkino Filmverleih | false |
| 39 | The A-Team | - | - | - | $25,399 | 84 | $873,867 | Aug 12 | 20th Century Fox International | false |
| 40 | Plato's Academy | - | - | - | $24,290 | 11 | $25,290 | Sep 10 | Polyfilm Verleih | false |
| 41 | Shrek Forever After | - | - | - | $23,382 | 102 | $4,589,527 | Jul 1 | Universal Pictures International (UPI) | false |
| 42 | When You're Strange | - | - | - | $22,966 | 4 | $30,417 | Sep 3 | - | false |
| 43 | Nothing Personal | - | - | - | $16,284 | 6 | $43,233 | Aug 20 | Polyfilm Verleih | false |
| 44 | The Hedgehog | - | - | - | $16,020 | 5 | $110,836 | Jun 3 | Constantin Film | false |
| 45 | Leaving | - | - | - | $14,824 | 3 | $17,992 | Sep 10 | Polyfilm Verleih | false |
| 46 | Crazy Heart | - | - | - | $14,752 | 9 | $150,917 | Jul 2 | - | false |
| 47 | Rammbock: Berlin Undead | - | - | - | $12,699 | 10 | $12,699 | Sep 10 | - | false |
| 48 | Freche Mädchen 2 | - | - | - | $10,907 | 43 | $256,854 | Aug 6 | Constantin Film | false |
| 49 | Splice 2010 Re-release | - | - | - | $9,928 | 12 | $28,288 | Aug 27 | Constantin Film | false |
| 50 | Knight and Day 2010 Re-release | - | - | - | $9,734 | 100 | $2,097,407 | Jul 22 | 20th Century Fox International | false |
| 51 | The Door 2010 Re-release | - | - | - | $9,222 | 7 | $9,472 | Sep 17 | Constantin Film | false |
| 52 | Autumn Gold | - | - | - | $8,245 | 3 | $10,616 | Sep 24 | - | false |
| 53 | Wild Grass | - | - | - | $6,814 | 7 | $29,605 | Aug 20 | Filmladen | false |
| 54 | Certified Copy | - | - | - | $6,791 | 2 | $27,033 | Sep 24 | Stadtkino Filmverleih | false |
| 55 | Domain | - | - | - | $2,380 | 2 | $8,716 | Sep 24 | Stadtkino Filmverleih | false |
| 56 | Earth Madness | - | - | - | $2,162 | 1 | $4,372 | Sep 3 | Stadtkino Filmverleih | false |
| 57 | Wonderful and Loved by All 2010 Re-release | - | - | - | $1,223 | 25 | $68,879 | Jul 30 | - | false |
| 58 | Coma | - | - | - | $876 | 1 | $4,061 | Sep 17 | Stadtkino Filmverleih | false |
| 59 | Salami Aleikum | - | - | - | $695 | 47 | $934,475 | Jan 1 | Stadtkino Filmverleih | false |
| 60 | Fantastic Mr. Fox | - | - | - | $578 | 12 | $65,786 | Jun 25 | 20th Century Fox International | false |
| 61 | The Fish Child 2010 Re-release | - | - | - | $416 | 2 | $3,562 | Aug 13 | Polyfilm Verleih | false |
| 62 | Episode 3: 'Enjoy Poverty' 2010 Re-release | - | - | - | $113 | 1 | $557 | Sep 17 | Stadtkino Filmverleih | false |
