| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Inglourious Basterds | - | - | - | $9,349,266 | 482 | $15,418,489 | Sep 18 | United International Pictures | false |
| 2 | District 9 | - | - | - | $6,105,842 | 357 | $7,023,330 | Sep 11 | Sony Pictures Releasing | false |
| 3 | He's Just Not That Into You | - | - | - | $5,911,593 | 336 | $6,788,630 | Sep 3 | TriPictures | false |
| 4 | Up | - | - | - | $4,703,847 | 603 | $37,052,520 | Jul 30 | Walt Disney Pictures | false |
| 5 | My Bloody Valentine | - | - | - | $4,064,651 | 310 | $4,593,087 | Sep 11 | TriPictures | false |
| 6 | The Hangover | - | - | - | $2,653,690 | 327 | $9,374,796 | Aug 14 | Warner Bros. | false |
| 7 | Surrogates | - | - | - | $2,418,237 | 320 | $6,176,221 | Sep 25 | Walt Disney Pictures | false |
| 8 | Year One | - | - | - | $2,195,275 | 222 | $4,173,713 | Aug 28 | Sony Pictures Releasing | false |
| 9 | Gamer | - | - | - | $2,046,453 | 302 | $2,049,947 | Sep 4 | - | false |
| 10 | Case 39 | - | - | - | $2,024,270 | 221 | $3,837,870 | Aug 28 | Paramount Pictures International | false |
| 11 | Fat People | - | - | - | $1,997,703 | 176 | $2,664,834 | Sep 11 | Alta Films | false |
| 12 | Public Enemies | - | - | - | $1,854,365 | 460 | $10,686,582 | Aug 14 | United International Pictures | false |
| 13 | Map of the Sounds of Tokyo | - | - | - | $1,574,631 | 170 | $2,990,991 | Aug 28 | Alta Films | false |
| 14 | Aliens in the Attic | - | - | - | $1,298,338 | 324 | $5,465,811 | Aug 14 | 20th Century Fox International | false |
| 15 | Guts | - | - | - | $1,003,283 | 166 | $1,023,161 | Sep 4 | Sony Pictures Releasing | false |
| 16 | Shorts | - | - | - | $991,277 | 165 | $1,754,478 | Aug 28 | Warner Bros. | false |
| 17 | Ice Age: Dawn of the Dinosaurs | - | - | - | $954,871 | 663 | $32,142,485 | Jul 2 | 20th Century Fox International | false |
| 18 | Spread | - | - | - | $953,653 | 203 | $2,052,392 | Aug 28 | Aurum Films | false |
| 19 | Funny People | - | - | - | $924,219 | 182 | $980,798 | Sep 4 | United International Pictures | false |
| 20 | The Girl with the Dragon Tattoo | - | - | - | $876,435 | 283 | $13,727,644 | May 29 | Vértigo Films | false |
| 21 | Jennifer's Body | - | - | - | $719,152 | 265 | $1,462,153 | Sep 25 | 20th Century Fox International | false |
| 22 | Bandslam | - | - | - | $628,832 | 125 | $749,455 | Sep 11 | Aurum Films | false |
| 23 | Frozen River | - | - | - | $579,126 | 36 | $722,067 | Sep 4 | Sagrera TV | false |
| 24 | Harry Potter and the Half-Blood Prince | - | - | - | $574,732 | 589 | $20,813,480 | Jul 15 | Warner Bros. | false |
| 25 | OceanWorld | - | - | - | $434,891 | 118 | $938,228 | Sep 25 | Wanda Visión S.A. | false |
| 26 | Gran Torino | - | - | - | $418,223 | 263 | $19,038,938 | Mar 6 | Warner Bros. | false |
| 27 | The Informant! | - | - | - | $392,762 | 104 | $789,433 | Sep 25 | Warner Bros. | false |
| 28 | A French Gigolo | - | - | - | $257,602 | 50 | $266,126 | Sep 4 | Vértigo Films | false |
| 29 | Antichrist | - | - | - | $202,897 | 80 | $770,255 | Aug 21 | Golem Distribución | false |
| 30 | The Proposal | - | - | - | $165,580 | 350 | $5,959,363 | Jul 9 | Walt Disney Pictures | false |
| 31 | Flores negras | - | - | - | $155,894 | 105 | $157,325 | Sep 18 | Filmax | false |
| 32 | G.I. Joe: The Rise of Cobra | - | - | - | $150,738 | 462 | $6,501,034 | Aug 7 | Paramount Pictures International | false |
| 33 | The Taking of Pelham 123 | - | - | - | $147,871 | 401 | $8,867,740 | Jul 24 | Sony Pictures Releasing | false |
| 34 | Motherhood | - | - | - | $114,026 | 104 | $353,440 | Aug 28 | DeAPlaneta | false |
| 35 | Departures | - | - | - | $107,342 | 35 | $726,311 | Jul 3 | Golem Distribución | false |
| 36 | Ex | - | - | - | $104,577 | 158 | $1,115,617 | Jul 24 | Notro Films | false |
| 37 | Mid-August Lunch | - | - | - | $91,427 | 31 | $1,272,844 | May 22 | Alta Films | false |
| 38 | Lilly the Witch: The Dragon and the Magic Book | - | - | - | $90,381 | 2,642 | $3,494,942 | Jun 12 | Walt Disney Pictures | false |
| 39 | 12 Rounds | - | - | - | $85,086 | 30 | $92,150 | Sep 11 | 20th Century Fox International | false |
| 40 | The First Day of the Rest of Your Life | - | - | - | $84,469 | 47 | $856,174 | Jun 19 | - | false |
| 41 | My Life in Ruins | - | - | - | $83,824 | 207 | $1,842,519 | Aug 7 | Manga Entertainment | false |
| 42 | The Haunting in Connecticut | - | - | - | $82,305 | 253 | $2,430,568 | Aug 7 | DeAPlaneta | false |
| 43 | Ong Bak 2 | - | - | - | $68,017 | 181 | $1,096,242 | Aug 21 | Aurum Films | false |
| 44 | Land of the Lost | - | - | - | $52,485 | 95 | $513,239 | Aug 21 | United International Pictures | false |
| 45 | Let's Get Lost 2009 Re-release | - | - | - | $49,260 | 3 | $99,046 | Sep 18 | Avalon | false |
| 46 | I Love You, Beth Cooper | - | - | - | $44,697 | 30 | $47,255 | Sep 18 | 20th Century Fox International | false |
| 47 | Taking Woodstock | - | - | - | $43,338 | 22 | $43,338 | Sep 25 | United International Pictures | false |
| 48 | The Drummer | - | - | - | $34,363 | 3 | $35,938 | Sep 11 | Karma Films | false |
| 49 | Still Walking | - | - | - | $29,526 | 4 | $386,649 | Jun 5 | Golem Distribución | false |
| 50 | Drag Me to Hell | - | - | - | $26,859 | 282 | $3,656,061 | Jul 31 | United International Pictures | false |
| 51 | Tear This Heart Out | - | - | - | $25,865 | 80 | $509,547 | Jul 24 | Wanda Visión S.A. | false |
| 52 | LOL (Laughing Out Loud) | - | - | - | $24,424 | 191 | $847,737 | Jun 26 | Alta Films | false |
| 53 | Satin Rouge 2009 Re-release | - | - | - | $24,279 | 4 | $118,389 | Jul 31 | Karma Films | false |
| 54 | Three Days with the Family | - | - | - | $22,887 | 30 | $382,763 | Jun 26 | - | false |
| 55 | Amazing Grace | - | - | - | $21,957 | 5 | $21,957 | Sep 11 | Filmax | false |
| 56 | The Life Before Her Eyes | - | - | - | $20,617 | 25 | $141,603 | Aug 21 | Manga Entertainment | false |
| 57 | Disgrace | - | - | - | $20,290 | 6 | $400,184 | Jul 31 | Golem Distribución | false |
| 58 | V.O.S. | - | - | - | $19,499 | 24 | $272,271 | Jul 10 | Alta Films | false |
| 59 | Owl and the Sparrow | - | - | - | $13,491 | 10 | $118,354 | Jul 24 | - | false |
| 60 | Small Country | - | - | - | $11,367 | 30 | $348,105 | Jul 24 | Alta Films | false |
| 61 | Friend Zone | - | - | - | $11,196 | 228 | $2,866,118 | Jul 3 | Manga Entertainment | false |
| 62 | The September Issue | - | - | - | $10,900 | 5 | $26,073 | Sep 25 | Avalon | false |
| 63 | Pájaros muertos | - | - | - | $10,125 | 24 | $10,125 | Sep 18 | - | false |
| 64 | A Boyfriend for My Wife | - | - | - | $9,367 | 49 | $512,380 | Jul 10 | - | false |
| 65 | Angels & Demons | - | - | - | $7,030 | 699 | $21,944,084 | May 15 | Sony Pictures Releasing | false |
| 66 | Pandora's Box | - | - | - | $6,798 | 20 | $332,081 | Jun 12 | Karma Films | false |
| 67 | The Year My Parents Went on Vacation | - | - | - | $6,678 | 23 | $123,551 | Aug 14 | Vértigo Films | false |
| 68 | Don't Look Down | - | - | - | $5,583 | 11 | $114,673 | Jul 17 | Karma Films | false |
| 69 | Brüno | - | - | - | $5,322 | 310 | $2,542,344 | Jul 10 | Sony Pictures Releasing | false |
| 70 | My Führer 2009 Re-release | - | - | - | $4,041 | 18 | $88,200 | Aug 7 | - | false |
| 71 | Lokas 2009 Re-release | - | - | - | $2,827 | 7 | $11,867 | Aug 28 | - | false |
| 72 | Seraphine | - | - | - | $2,478 | 30 | $566,810 | May 8 | Golem Distribución | false |
| 73 | The Visitor | - | - | - | $2,272 | 52 | $1,514,424 | Mar 13 | Karma Films | false |
| 74 | Sex Drive | - | - | - | $2,133 | 230 | $704,430 | Jul 31 | Paramount Pictures International | false |
| 75 | Glory to the Filmmaker! | - | - | - | $1,944 | 3 | $7,301 | Aug 28 | - | false |
| 76 | Beyond a Reasonable Doubt | - | - | - | $1,903 | 204 | $2,257,921 | Jul 10 | DeAPlaneta | false |
| 77 | The Sky Crawlers | - | - | - | $916 | 1 | $916 | Sep 25 | - | false |
| 78 | How to Lose Friends & Alienate People | - | - | - | $837 | 175 | $976,030 | Jul 24 | Warner Bros. | false |
| 79 | Transformers: Revenge of the Fallen | - | - | - | $516 | 598 | $8,698,257 | Jun 24 | Paramount Pictures International | false |
| 80 | Ashes of Time | - | - | - | $505 | 7 | $57,060 | Jul 31 | Vértigo Films | false |
| 81 | Labor Pains | - | - | - | $471 | 100 | $287,260 | Jul 31 | DeAPlaneta | false |
| 82 | Como Fazer Um Filme de Amor | - | - | - | $364 | 3 | $2,748 | Sep 25 | - | false |
| 83 | Paranoid Park | - | - | - | $270 | 2 | $63,314 | Jul 10 | - | false |
| 84 | The Last House on the Left | - | - | - | $226 | 252 | $2,886,802 | Jul 3 | United International Pictures | false |
| 85 | Coco Before Chanel | - | - | - | $34 | 139 | $2,448,911 | Jun 5 | Warner Bros. | false |
