| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | A Boyfriend for My Wife | - | - | - | $2,362,527 | 91 | $5,655,910 | Aug 14 | Walt Disney Pictures | false |
| 2 | Tropic Thunder | - | - | - | $1,052,462 | 48 | $1,349,571 | Sep 4 | United International Pictures | false |
| 3 | Mamma Mia! | - | - | - | $730,324 | 50 | $178,082 | Aug 21 | United International Pictures | false |
| 4 | Tinker Bell | - | - | - | $590,609 | 58 | $788,678 | Sep 11 | Walt Disney Pictures | false |
| 5 | Reasons for Not Falling in Love | - | - | - | $525,804 | 44 | $542,931 | Sep 4 | Distribution Company | false |
| 6 | You Don't Mess with the Zohan | - | - | - | $360,110 | 30 | $723,308 | Sep 18 | Sony Pictures Releasing | false |
| 7 | Wanted | - | - | - | $335,974 | 46 | $583,615 | Aug 28 | United International Pictures | false |
| 8 | Superhero Movie | - | - | - | $288,514 | 40 | $334,873 | Sep 11 | Pachamama Cine | false |
| 9 | The Strangers | - | - | - | $272,035 | 32 | $368,904 | Sep 11 | Distribution Company | false |
| 10 | Taken | - | - | - | $236,296 | 30 | $572,787 | Sep 18 | 20th Century Fox International | false |
| 11 | Babylon A.D. | - | - | - | $200,336 | 30 | $261,450 | Sep 4 | 20th Century Fox International | false |
| 12 | The Dark Knight | - | - | - | $169,058 | 160 | $5,480,477 | Jul 17 | Warner Bros. | false |
| 13 | REC | - | - | - | $166,926 | 20 | $225,119 | Sep 11 | CDI Films | false |
| 14 | My Brother is an Only Child | - | - | - | $125,796 | 13 | $222,886 | Sep 18 | Alfa Films | false |
| 15 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | - | - | - | $123,825 | 2 | $157,244 | Sep 4 | Walt Disney Pictures | false |
| 16 | The X Files: I Want to Believe | - | - | - | $123,090 | 45 | $706,287 | Aug 14 | 20th Century Fox International | false |
| 17 | Four Minutes | - | - | - | $108,417 | 14 | $159,960 | Aug 28 | Alfa Films | false |
| 18 | The Mummy: Tomb of the Dragon Emperor | - | - | - | $105,048 | 127 | $2,893,362 | Jul 31 | United International Pictures | false |
| 19 | La próxima estación | - | - | - | $90,008 | 13 | $120,249 | Sep 4 | Primer Plano Film Group | false |
| 20 | Dan in Real Life | - | - | - | $85,313 | 32 | $213,204 | Sep 25 | Distribution Company | false |
| 21 | L'invité | - | - | - | $83,196 | 15 | $127,719 | Aug 28 | Pachamama Cine | false |
| 22 | Eagle Eye | - | - | - | $82,109 | 40 | $189,322 | Sep 25 | United International Pictures | false |
| 23 | The Bottle | - | - | - | $80,326 | 24 | $81,944 | Sep 11 | Primer Plano Film Group | false |
| 24 | WALL·E | - | - | - | $66,990 | 167 | $4,664,019 | Jul 10 | Walt Disney Pictures | false |
| 25 | Meet Dave | - | - | - | $51,001 | 29 | $264,944 | Aug 7 | 20th Century Fox International | false |
| 26 | Star Wars: The Clone Wars | - | - | - | $49,189 | 43 | $236,497 | Aug 14 | Warner Bros. | false |
| 27 | The Headless Woman | - | - | - | $49,067 | 17 | $129,638 | Aug 21 | Distribution Company | false |
| 28 | Black Sheep | - | - | - | $47,226 | 31 | $148,517 | Aug 21 | Pachamama Cine | false |
| 29 | Run Fatboy Run | - | - | - | $45,061 | 19 | $80,421 | Aug 28 | Distribution Company | false |
| 30 | Kung Fu Panda | - | - | - | $39,022 | 153 | $5,038,274 | Jul 3 | United International Pictures | false |
| 31 | Before the Devil Knows You're Dead | - | - | - | $32,812 | 18 | $595,095 | Jul 10 | Distribution Company | false |
| 32 | Manual of Love 2008 Re-release | - | - | - | $28,698 | 9 | $136,530 | Sep 25 | Notro Films | false |
| 33 | The Other Boleyn Girl | - | - | - | $26,720 | 26 | $339,213 | Aug 7 | Distribution Company | false |
| 34 | Francesca | - | - | - | $25,891 | 6 | $181,839 | Jul 17 | IFA | false |
| 35 | Hancock | - | - | - | $23,908 | 89 | $2,309,663 | Jul 3 | Sony Pictures Releasing | false |
| 36 | Nim's Island | - | - | - | $23,250 | 38 | $166,142 | Aug 7 | United International Pictures | false |
| 37 | Chaos | - | - | - | $22,029 | 16 | $95,026 | Aug 14 | - | false |
| 38 | You, the Living | - | - | - | $20,489 | 7 | $20,807 | Sep 4 | Zeta Films | false |
| 39 | Irina Palm | - | - | - | $20,131 | 11 | $43,250 | Sep 25 | Alfa Films | false |
| 40 | Los superagentes, nueva generación | - | - | - | $19,616 | 75 | $864,512 | Jul 17 | Argentina Sono Film S.A.C.I. | false |
| 41 | Lars and the Real Girl | - | - | - | $16,839 | 18 | $74,502 | Aug 21 | Impacto Cine | false |
| 42 | The Chronicles of Narnia: Prince Caspian | - | - | - | $15,042 | 189 | $3,702,166 | Jun 12 | Walt Disney Pictures | false |
| 43 | 100% lucha, la película | - | - | - | $14,237 | 53 | $874,285 | Jul 10 | Primer Plano Film Group | false |
| 44 | Cassandra's Dream | - | - | - | $13,771 | 30 | $583,973 | Jun 5 | Alfa Films | false |
| 45 | A Girl Cut in Two | - | - | - | $13,702 | 20 | $286,698 | Jul 24 | Alfa Films | false |
| 46 | The Happening | - | - | - | $13,514 | 50 | $1,341,309 | Jun 19 | 20th Century Fox International | false |
| 47 | Climates | - | - | - | $13,187 | 2 | $19,214 | Aug 28 | 791 Cine | false |
| 48 | The Diving Bell and the Butterfly | - | - | - | $12,567 | 10 | $105,015 | Aug 14 | Alfa Films | false |
| 49 | Get Smart | - | - | - | $11,809 | 107 | $2,252,024 | Jun 26 | Warner Bros. | false |
| 50 | High School Musical: El Desafío | - | - | - | $10,812 | 141 | $1,766,913 | Jul 17 | Walt Disney Pictures | false |
| 51 | Hunting and Gathering | - | - | - | $10,508 | 8 | $21,660 | Aug 28 | Notro Films | false |
| 52 | The Incredible Hulk | - | - | - | $10,256 | 80 | $935,727 | Jun 19 | United International Pictures | false |
| 53 | Twentieth Century | - | - | - | $9,800 | 7 | $9,800 | Sep 4 | Zeta Films | false |
| 54 | Journey to the Center of the Earth | - | - | - | $9,759 | 55 | $1,311,200 | Jul 17 | Distribution Company | false |
| 55 | Death at a Funeral | - | - | - | $9,669 | 33 | $2,153,078 | Mar 6 | Compañía General de la Imagen (CGI) | false |
| 56 | The Price to Pay | - | - | - | $8,614 | 12 | $131,936 | Jul 31 | Impacto Cine | false |
| 57 | Valentina: The Movie | - | - | - | $8,298 | 52 | $61,224 | Jul 10 | Pachamama Cine | false |
| 58 | Golden Door | - | - | - | $7,327 | 3 | $111,029 | Sep 18 | Primer Plano Film Group | false |
| 59 | A Guide to Recognizing Your Saints | - | - | - | $7,063 | 6 | $14,087 | Aug 28 | CDI Films | false |
| 60 | Under the Same Moon | - | - | - | $5,926 | 12 | $27,572 | Aug 21 | 20th Century Fox International | false |
| 61 | 88 Minutes | - | - | - | $5,653 | 31 | $396,117 | May 29 | Distribution Company | false |
| 62 | My Blueberry Nights | - | - | - | $4,805 | 19 | $226,167 | Jun 26 | Distribution Company | false |
| 63 | I Served the King of England | - | - | - | $4,198 | 10 | $69,163 | Jul 31 | Distribution Company | false |
| 64 | The Mist | - | - | - | $4,049 | 31 | $428,010 | Jun 5 | Distribution Company | false |
| 65 | Comedy of Innocence | - | - | - | $3,985 | 4 | $20,045 | Oct 25 | Primer Plano Film Group | false |
| 66 | A Secret | - | - | - | $3,161 | 13 | $207,016 | Jun 19 | Alfa Films | false |
| 67 | Aaltra | - | - | - | $2,913 | 2 | $6,083 | Sep 25 | Vera Films | false |
| 68 | The Band's Visit | - | - | - | $2,328 | 13 | $136,627 | Jul 10 | Alfa Films | false |
| 69 | Backstage 2008 Re-release | - | - | - | $2,057 | 3 | $2,057 | Sep 11 | Distribution Company | false |
| 70 | Conversations with My Gardener | - | - | - | $2,042 | 14 | $221,688 | Apr 24 | Alfa Films | false |
| 71 | Abrígate | - | - | - | $1,991 | 3 | $3,124 | Sep 11 | Walt Disney Pictures | false |
| 72 | Saint Ralph 2008 Re-release | - | - | - | $1,229 | 5 | $1,229 | Sep 25 | Distribution Company | false |
| 73 | Paranoid Park | - | - | - | $1,144 | 3 | $10,033 | Aug 21 | Alfa Films | false |
| 74 | U2 3D | - | - | - | $503 | 1 | $140,453 | Mar 27 | IMAX | false |
| 75 | Awake | - | - | - | $182 | 31 | $274,878 | May 15 | Distribution Company | false |
| 76 | The Nest | - | - | - | $51 | 39 | $1,008,755 | Apr 24 | Distribution Company | false |
| 77 | La león | - | - | - | $12 | 4 | $8,333 | Jun 12 | 791 Cine | false |
