| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Devil Wears Prada | - | - | - | $3,716,026 | 323 | $11,614,255 | - | 20th Century Fox International | false |
| 2 | Monster House | - | - | - | $3,496,044 | 266 | $6,136,400 | Sep 14 | Sony Pictures Releasing | false |
| 3 | Talladega Nights: The Ballad of Ricky Bobby | - | - | - | $2,674,453 | 2,890 | $4,534,472 | - | Sony Pictures Releasing | false |
| 4 | John Tucker Must Die | - | - | - | $2,517,034 | 177 | $2,894,839 | Sep 7 | 20th Century Fox International | false |
| 5 | Garfield: A Tail of Two Kitties | - | - | - | $2,292,647 | 204 | $5,369,874 | Sep 7 | 20th Century Fox International | false |
| 6 | Kenny | - | - | - | $2,168,563 | 124 | $6,117,952 | Aug 17 | Madman Entertainment | false |
| 7 | Nacho Libre | - | - | - | $2,002,381 | 232 | $2,424,764 | Sep 14 | United International Pictures | false |
| 8 | Silent Hill | - | - | - | $1,496,627 | 155 | $1,496,627 | Aug 31 | United International Pictures | false |
| 9 | An Inconvenient Truth | - | - | - | $1,390,517 | 63 | $3,184,352 | Sep 14 | United International Pictures | false |
| 10 | Step Up | - | - | - | $1,285,611 | 158 | $5,047,655 | Sep 28 | United International Pictures | false |
| 11 | Friends with Money | - | - | - | $1,239,434 | 44 | $1,370,408 | Aug 31 | Roadshow Films | false |
| 12 | Barnyard | - | - | - | $1,212,360 | 206 | $3,094,601 | Sep 21 | United International Pictures | false |
| 13 | Thank You for Smoking | - | - | - | $1,206,946 | 90 | $2,221,170 | Aug 24 | 20th Century Fox International | false |
| 14 | Stormbreaker | - | - | - | $1,047,973 | 190 | $1,886,398 | Sep 21 | Roadshow Films | false |
| 15 | Snakes on a Plane | - | - | - | $1,003,469 | 225 | $2,207,877 | Aug 24 | Roadshow Films | false |
| 16 | Material Girls | - | - | - | $1,000,863 | 130 | $1,361,960 | Sep 14 | Hoyts Distribution | false |
| 17 | Lady in the Water | - | - | - | $917,946 | 232 | $991,678 | Sep 7 | Warner Bros. | false |
| 18 | DOA: Dead or Alive | - | - | - | $880,039 | 139 | $977,424 | Sep 7 | United International Pictures | false |
| 19 | The Wild | - | - | - | $819,729 | 254 | $2,739,903 | Sep 28 | Buena Vista International | false |
| 20 | Clerks II | - | - | - | $733,918 | 124 | $797,522 | Aug 31 | Roadshow Films | false |
| 21 | You, Me and Dupree | - | - | - | $714,083 | 247 | $7,775,353 | Jul 27 | United International Pictures | false |
| 22 | Hoodwinked | - | - | - | $601,952 | 206 | $4,166,936 | Aug 3 | Roadshow Films | false |
| 23 | Miami Vice | - | - | - | $585,071 | 302 | $5,206,936 | Aug 10 | United International Pictures | false |
| 24 | The Ant Bully | - | - | - | $562,594 | 211 | $2,006,114 | Sep 28 | Warner Bros. | false |
| 25 | Fearless | - | - | - | $497,446 | 140 | $1,358,185 | Aug 24 | United International Pictures | false |
| 26 | Jindabyne | - | - | - | $488,832 | 86 | $4,165,518 | Jul 20 | Roadshow Films | false |
| 27 | Pirates of the Caribbean: Dead Man's Chest | - | - | - | $421,621 | 490 | $28,477,460 | Jul 6 | Buena Vista International | false |
| 28 | United 93 | - | - | - | $271,727 | 195 | $1,383,583 | Aug 17 | United International Pictures | false |
| 29 | The Wind that Shakes the Barley | - | - | - | $241,903 | 26 | $633,713 | Sep 21 | Dendy Films | false |
| 30 | Curious George | - | - | - | $232,397 | 198 | $880,828 | Aug 17 | United International Pictures | false |
| 31 | Beerfest | - | - | - | $122,220 | 101 | $398,997 | Sep 28 | Warner Bros. | false |
| 32 | The Lake House | - | - | - | $107,519 | 208 | $4,373,186 | Jul 27 | Roadshow Films | false |
| 33 | Ten Canoes | - | - | - | $61,946 | 65 | $2,519,614 | - | Palace Films | false |
| 34 | Lage Raho Munna Bhai | - | - | - | $57,244 | 8 | $57,244 | Aug 31 | Eros Worldwide | false |
| 35 | 48 Shades | - | - | - | $53,972 | 50 | $70,901 | Aug 31 | Buena Vista International | false |
| 36 | Aquamarine | - | - | - | $51,661 | 81 | $198,247 | Sep 28 | 20th Century Fox International | false |
| 37 | Man About Town | - | - | - | $51,121 | 80 | $51,121 | Aug 31 | Hoyts Distribution | false |
| 38 | Unfolding Florence: The Many Lives of Florence Broadhurst | - | - | - | $40,896 | 15 | $122,660 | Aug 24 | Dendy Films | false |
