| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Lake House | - | - | - | $487,182 | 28 | $720,346 | Aug 31 | Warner Bros. | false |
| 2 | Miami Vice | - | - | - | $385,709 | 50 | $465,908 | Sep 7 | United International Pictures | false |
| 3 | The Devil Wears Prada | - | - | - | $349,590 | 36 | $951,335 | Sep 21 | 20th Century Fox International | false |
| 4 | Volver | - | - | - | $308,076 | 31 | $956,119 | Aug 10 | 20th Century Fox International | false |
| 5 | Click | - | - | - | $303,183 | 31 | $710,028 | Aug 17 | Sony Pictures Releasing | false |
| 6 | Fuerza aérea sociedad anónima | - | - | - | $281,636 | 19 | $297,366 | Aug 31 | Distribution Company | false |
| 7 | United 93 | - | - | - | $244,706 | 20 | $321,365 | Aug 31 | United International Pictures | false |
| 8 | Lady in the Water | - | - | - | $229,937 | 25 | $399,003 | Aug 24 | Warner Bros. | false |
| 9 | Snakes on a Plane | - | - | - | $200,597 | 49 | $272,200 | Sep 14 | Distribution Company | false |
| 10 | The Break-Up | - | - | - | $199,462 | 40 | $960,763 | Aug 3 | United International Pictures | false |
| 11 | The Sentinel | - | - | - | $185,661 | 41 | $567,876 | Aug 17 | 20th Century Fox International | false |
| 12 | Monster House | - | - | - | $184,972 | 48 | $555,676 | Aug 10 | Sony Pictures Releasing | false |
| 13 | The Hands | - | - | - | $183,864 | 48 | $513,709 | Aug 10 | Primer Plano Film Group | false |
| 14 | The Jacket | - | - | - | $153,566 | 28 | $205,285 | Sep 7 | Alfa Films | false |
| 15 | 16 Blocks | - | - | - | $147,065 | 31 | $550,731 | Aug 10 | Distribution Company | false |
| 16 | Pirates of the Caribbean: Dead Man's Chest | - | - | - | $116,226 | 115 | $4,409,190 | Jul 20 | Buena Vista International | false |
| 17 | My Super Ex-Girlfriend | - | - | - | $113,537 | 23 | $167,199 | Sep 7 | 20th Century Fox International | false |
| 18 | Transamerica | - | - | - | $106,501 | 19 | $153,455 | Sep 14 | Alfa Films | false |
| 19 | The Fast and the Furious: Tokyo Drift | - | - | - | $103,433 | 30 | $300,714 | Aug 17 | United International Pictures | false |
| 20 | You, Me and Dupree | - | - | - | $94,687 | 30 | $553,132 | Sep 28 | United International Pictures | false |
| 21 | The Ant Bully | - | - | - | $77,547 | 34 | $179,878 | Aug 17 | Warner Bros. | false |
| 22 | Que sea rock | - | - | - | $37,751 | 40 | $37,751 | Sep 7 | Aries Cinematográfica Argentina | false |
| 23 | The Tiger and the Snow | - | - | - | $30,253 | 19 | $93,280 | Sep 28 | Distribution Company | false |
| 24 | Cry Wolf | - | - | - | $27,372 | 16 | $69,261 | Aug 31 | Distribution Company | false |
| 25 | Sofabed | - | - | - | $19,616 | 23 | $19,616 | Aug 31 | Primer Plano Film Group | false |
| 26 | The Road to San Diego | - | - | - | $18,381 | 21 | $18,381 | Sep 14 | 20th Century Fox International | false |
| 27 | Open Water 2: Adrift | - | - | - | $18,112 | 31 | $59,720 | Aug 24 | Alfa Films | false |
| 28 | A través de tus ojos | - | - | - | $14,493 | 10 | $14,493 | Sep 7 | Distribution Company | false |
| 29 | Mientras tanto | - | - | - | $13,979 | 10 | $13,979 | Sep 28 | 791 Cine | false |
| 30 | Princesses | - | - | - | $11,074 | 12 | $26,394 | Sep 28 | Alfa Films | false |
| 31 | What the #$*! Do We (K)now!? 2005 Re-release | - | - | - | $10,597 | 8 | $42,476 | Sep 14 | Pachamama Cine | false |
| 32 | Jews in Space or Why Is this Night Different from All Other Nights? | - | - | - | $10,365 | 5 | $10,365 | Sep 7 | Primer Plano Film Group | false |
| 33 | Over the Hedge | - | - | - | $10,175 | 145 | $2,652,731 | Jul 13 | United International Pictures | false |
| 34 | Prime | - | - | - | $9,909 | 28 | $1,310,973 | May 25 | Distribution Company | false |
| 35 | Bañeros III, todopoderosos | - | - | - | $9,790 | 105 | $3,018,987 | Jul 13 | Argentina Sono Film S.A.C.I. | false |
