| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Madagascar | - | - | - | $22,257,955 | 470 | $28,044,781 | Sep 2 | United International Pictures | false |
| 2 | Fantastic Four | - | - | - | $7,864,217 | 482 | $12,412,822 | Sep 16 | 20th Century Fox International | false |
| 3 | Don't Tell | - | - | - | $4,613,974 | 282 | $5,859,312 | Sep 9 | 01 Distribution | false |
| 4 | Charlie and the Chocolate Factory | - | - | - | $3,946,540 | 389 | $12,487,531 | Sep 23 | Warner Bros. | false |
| 5 | Cinderella Man | - | - | - | $3,077,201 | 377 | $3,401,719 | Sep 9 | Buena Vista International | false |
| 6 | The Days of Abandonment | - | - | - | $2,347,270 | 226 | $3,740,380 | Sep 16 | Medusa Distribuzione | false |
| 7 | Wedding Crashers | - | - | - | $2,278,169 | 318 | $2,550,388 | Sep 9 | Eagle Pictures | false |
| 8 | Good Night, and Good Luck. | - | - | - | $1,829,405 | 195 | $2,890,928 | Sep 16 | Mediafilm | false |
| 9 | The Island | - | - | - | $1,673,004 | 309 | $3,737,321 | Aug 26 | Warner Bros. | false |
| 10 | The Skeleton Key | - | - | - | $1,140,285 | 128 | $1,275,206 | Sep 9 | United International Pictures | false |
| 11 | Herbie: Fully Loaded | - | - | - | $1,034,840 | 354 | $3,241,316 | Aug 26 | Buena Vista International | false |
| 12 | Seven Swords | - | - | - | $1,015,611 | 239 | $1,054,623 | Sep 2 | Medusa Distribuzione | false |
| 13 | Mindhunters | - | - | - | $996,831 | 228 | $2,449,850 | Aug 26 | Eagle Pictures | false |
| 14 | The Dukes of Hazzard | - | - | - | $949,599 | 106 | $949,599 | Sep 2 | Warner Bros. | false |
| 15 | War of the Worlds | - | - | - | $793,509 | 567 | $17,295,956 | Jun 29 | United International Pictures | false |
| 16 | Viva Zapatero! | - | - | - | $686,739 | 78 | $1,890,632 | Sep 16 | Lucky Red | false |
| 17 | Howl's Moving Castle | - | - | - | $654,934 | 81 | $654,934 | Sep 9 | Lucky Red | false |
| 18 | Stealth | - | - | - | $353,082 | 170 | $353,082 | Sep 2 | - | false |
| 19 | The Amityville Horror | - | - | - | $265,523 | 197 | $1,957,932 | Aug 19 | Buena Vista International | false |
| 20 | Changing Times | - | - | - | $231,790 | 49 | $384,690 | Aug 26 | Mikado Film | false |
| 21 | Creep | - | - | - | $223,269 | 80 | $292,050 | Sep 23 | Italian International Film | false |
| 22 | Mean Spirit 2005 Re-release | - | - | - | $223,231 | 101 | $293,549 | Sep 23 | Medusa Distribuzione | false |
| 23 | The SpongeBob SquarePants Movie | - | - | - | $221,751 | 147 | $573,082 | Sep 23 | United International Pictures | false |
| 24 | Gabrielle | - | - | - | $195,082 | 35 | $195,082 | Sep 9 | Mikado Film | false |
| 25 | Nine Lives | - | - | - | $167,598 | 39 | $167,598 | Sep 2 | Mikado Film | false |
| 26 | Deuce Bigalow: European Gigolo | - | - | - | $153,965 | 101 | $502,296 | Aug 26 | Sony Pictures Releasing | false |
| 27 | The Bridesmaid | - | - | - | $100,685 | 40 | $196,476 | Sep 23 | BIM Distribuzione | false |
| 28 | A Lot Like Love | - | - | - | $80,564 | 141 | $444,670 | Aug 26 | Italian International Film | false |
| 29 | 20 Centimeters | - | - | - | $78,018 | 30 | $153,657 | Aug 26 | Lady Film | false |
| 30 | Guess Who | - | - | - | $55,475 | 111 | $695,840 | Aug 19 | 20th Century Fox International | false |
| 31 | Salvador Allende | - | - | - | $53,590 | 9 | $53,590 | Sep 2 | Fandango | false |
| 32 | Dear Wendy | - | - | - | $26,545 | 41 | $26,545 | Sep 23 | Eagle Pictures | false |
| 33 | La passione di Giosué l'Ebreo | - | - | - | $22,859 | 43 | $22,859 | Sep 9 | Istituto Luce | false |
| 34 | Concorso di colpa | - | - | - | $17,133 | 48 | $79,780 | Aug 26 | Istituto Luce | false |
| 35 | Raise Your Voice | - | - | - | $13,335 | 179 | $818,660 | Aug 19 | Eagle Pictures | false |
| 36 | Good Life Delivery 2005 Re-release | - | - | - | $8,441 | 7 | $8,441 | Sep 2 | Italian International Film | false |
| 37 | The Life and Death of Peter Sellers | - | - | - | $7,914 | 107 | $260,409 | Aug 19 | Lucky Red | false |
