| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Hotel Transylvania 2 | - | - | - | $12,107,539 | 119 | $24,966,016 | Sep 25 | Sony Pictures Releasing | false |
| 2 | The Martian | - | - | - | $2,959,039 | 31 | $3,441,610 | Oct 2 | 20th Century Fox International | false |
| 3 | Maze Runner: The Scorch Trials | - | - | - | $1,813,964 | 81 | $5,208,364 | Sep 18 | 20th Century Fox International | false |
| 4 | Everest | - | - | - | $1,578,013 | 46 | $2,538,157 | Sep 25 | United International Pictures | false |
| 5 | The Walk | - | - | - | $1,225,308 | 46 | $2,188,956 | Oct 16 | Sony Pictures Releasing | false |
| 6 | Pan | - | - | - | $1,225,117 | 33 | $2,862,934 | Oct 9 | Warner Bros. | false |
| 7 | The Intern | - | - | - | $796,009 | 33 | $2,866,948 | Oct 23 | Warner Bros. | false |
| 8 | The 33 | - | - | - | $494,458 | 23 | $1,105,820 | Oct 9 | 20th Century Fox International | false |
| 9 | Pixels | - | - | - | $459,277 | 67 | $10,106,090 | Jul 23 | Sony Pictures Releasing | false |
| 10 | Knock Knock | - | - | - | $187,558 | 9 | $514,837 | Oct 9 | - | false |
| 11 | Inside Out | - | - | - | $160,236 | 109 | $25,432,065 | Jun 19 | Walt Disney Pictures | false |
| 12 | Hitman: Agent 47 | - | - | - | $130,285 | 57 | $2,441,184 | Sep 4 | 20th Century Fox International | false |
| 13 | Jessabelle | - | - | - | $129,713 | 19 | $400,604 | Sep 18 | Cinematográfica Blancica (CB) | false |
| 14 | Fantastic Four | - | - | - | $128,960 | 71 | $8,043,460 | Aug 21 | 20th Century Fox International | false |
| 15 | Insidious: Chapter 3 | - | - | - | $124,491 | 33 | $2,571,801 | Jun 26 | Sony Pictures Releasing | false |
| 16 | Ant-Man | - | - | - | $119,531 | 58 | $6,781,787 | Jul 15 | Walt Disney Pictures | false |
| 17 | Minions | - | - | - | $106,477 | 117 | $27,015,386 | Jul 10 | United International Pictures | false |
| 18 | Magic Mike XXL | - | - | - | $84,666 | 34 | $438,073 | Sep 18 | Warner Bros. | false |
| 19 | Leviathan | - | - | - | $65,143 | 2 | $70,565 | Sep 25 | - | false |
| 20 | Vacation | - | - | - | $64,293 | 31 | $2,421,226 | Jul 31 | Warner Bros. | false |
| 21 | Ricki and the Flash | - | - | - | $51,363 | 36 | $436,923 | Sep 11 | Sony Pictures Releasing | false |
| 22 | 1,000 Times Good Night | - | - | - | $28,820 | 14 | $382,067 | Aug 28 | - | false |
| 23 | Unfriended | - | - | - | $26,602 | 21 | $626,111 | Aug 21 | United International Pictures | false |
| 24 | Sinister 2 | - | - | - | $18,427 | 28 | $821,425 | Sep 4 | Cinematográfica Blancica (CB) | false |
| 25 | Paul Blart: Mall Cop 2 | - | - | - | $14,454 | 58 | $5,222,889 | Apr 17 | Sony Pictures Releasing | false |
| 26 | All Creatures Big And Small 2015 Re-release | - | - | - | $13,664 | 43 | $2,044,197 | Jul 31 | - | false |
| 27 | Mission: Impossible - Rogue Nation | - | - | - | $9,071 | 61 | $5,407,042 | Jul 31 | United International Pictures | false |
| 28 | Coming Home | - | - | - | $5,684 | 3 | $43,706 | Sep 18 | Sony Pictures Releasing | false |
| 29 | Annie | - | - | - | $1,221 | 53 | $1,984,643 | Mar 6 | Sony Pictures Releasing | false |
