| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Hotel Transylvania 2 | - | - | - | $5,688,653 | 213 | $2,438,444 | Sep 24 | United International Pictures | false |
| 2 | The Martian | - | - | - | $2,423,054 | 86 | $2,521,251 | Oct 1 | 20th Century Fox International | false |
| 3 | Truman | - | - | - | $1,487,795 | 159 | $2,363,282 | Sep 24 | Walt Disney Pictures | false |
| 4 | Pan | - | - | - | $1,184,091 | 159 | $1,211,152 | Oct 8 | Warner Bros. | false |
| 5 | Paranormal Activity: The Ghost Dimension | - | - | - | $958,618 | 102 | $2,408,119 | Oct 29 | United International Pictures | false |
| 6 | Crimson Peak | - | - | - | $891,200 | 63 | $929,644 | Oct 15 | United International Pictures | false |
| 7 | No Escape | - | - | - | $828,111 | 59 | $848,854 | Oct 8 | - | false |
| 8 | Irrational Man | - | - | - | $769,237 | 57 | $815,783 | Oct 1 | - | false |
| 9 | The Intern | - | - | - | $703,143 | 55 | $1,301,285 | Sep 24 | Warner Bros. | false |
| 10 | Everest | - | - | - | $632,972 | 87 | $2,445,099 | Sep 17 | United International Pictures | false |
| 11 | Black Mass | - | - | - | $581,736 | 107 | $718,398 | Oct 22 | Warner Bros. | false |
| 12 | The Walk | - | - | - | $558,718 | 75 | $559,051 | Oct 8 | Sony Pictures Releasing | false |
| 13 | The Clan | - | - | - | $523,201 | 297 | $10,360,307 | Aug 13 | 20th Century Fox International | false |
| 14 | Goosebumps | - | - | - | $471,783 | 141 | $1,225,023 | Oct 29 | Sony Pictures Releasing | false |
| 15 | Furious 7 | - | - | - | $421,580 | 433 | $10,494,030 | Apr 2 | United International Pictures | false |
| 16 | Bridge of Spies | - | - | - | $393,219 | 71 | $1,291,043 | Oct 29 | 20th Century Fox International | false |
| 17 | Sicario | - | - | - | $331,091 | 32 | $332,549 | Oct 8 | Alfa Films | false |
| 18 | Maze Runner: The Scorch Trials | - | - | - | $311,315 | 196 | $2,551,164 | Sep 10 | 20th Century Fox International | false |
| 19 | Unfriended | - | - | - | $261,135 | 34 | $517,364 | Sep 24 | United International Pictures | false |
| 20 | All Creatures Big And Small 2015 Re-release | - | - | - | $150,182 | 139 | $157,480 | Oct 15 | Alfa Films | false |
| 21 | El espejo de los otros | - | - | - | $134,203 | 147 | $961,433 | Sep 3 | Walt Disney Pictures | false |
| 22 | Pixels | - | - | - | $127,179 | 217 | $7,911,909 | Jul 23 | Sony Pictures Releasing | false |
| 23 | American Ultra | - | - | - | $106,700 | 43 | $112,587 | Oct 15 | - | false |
| 24 | The Gift | - | - | - | $104,049 | 35 | $104,556 | Oct 8 | Distribution Company | false |
| 25 | Roger Waters: The Wall | - | - | - | $85,157 | 6 | $112,488 | Oct 1 | - | false |
| 26 | Two Days, One Night | - | - | - | $75,543 | 19 | $91,551 | Oct 22 | Distribution Company | false |
| 27 | Cinderella | - | - | - | $72,935 | 268 | $1,368,674 | Mar 19 | Walt Disney Pictures | false |
| 28 | Ant-Man | - | - | - | $62,318 | 213 | $4,126,139 | Jul 16 | Walt Disney Pictures | false |
| 29 | We Are Your Friends | - | - | - | $60,209 | 37 | $60,209 | Oct 15 | - | false |
| 30 | The Little Prince | - | - | - | $43,241 | 196 | $964,460 | Aug 20 | Alfa Films | false |
| 31 | Demonic | - | - | - | $25,773 | 76 | $497,618 | Sep 10 | Distribution Company | false |
| 32 | Victoria 2015 Re-release | - | - | - | $15,889 | 10 | $16,214 | Oct 1 | - | false |
| 33 | Out of the Dark | - | - | - | $14,556 | 70 | $203,320 | Sep 17 | - | false |
| 34 | Indio, La Pelicula | - | - | - | $13,415 | 12 | $222,429 | Oct 2 | - | false |
| 35 | Labyrinth of Lies | - | - | - | $12,471 | 17 | $90,117 | Sep 17 | CDI Films | false |
| 36 | Inside Out | - | - | - | $12,384 | 335 | $11,241,015 | Jun 18 | Walt Disney Pictures | false |
| 37 | The Salt of the Earth | - | - | - | $9,352 | 13 | $56,628 | Aug 27 | - | false |
| 38 | My Friend from the Park | - | - | - | $7,352 | 16 | $27,216 | Sep 17 | Primer Plano Film Group | false |
| 39 | Minions | - | - | - | $7,320 | 333 | $36,154,412 | Jul 2 | United International Pictures | false |
| 40 | Bergoglio, the Pope Francis | - | - | - | $6,811 | 139 | $234,717 | Sep 10 | Walt Disney Pictures | false |
| 41 | The Kindergarten Teacher | - | - | - | $5,986 | 10 | $83,325 | Sep 17 | Zeta Films | false |
| 42 | Ricki and the Flash | - | - | - | $5,915 | 70 | $320,555 | Sep 10 | Sony Pictures Releasing | false |
| 43 | Jurassic World | - | - | - | $5,471 | 262 | $15,418,925 | Jun 11 | Universal Pictures International (UPI) | false |
| 44 | San Andreas | - | - | - | $3,877 | 209 | $7,211,836 | May 28 | Warner Bros. | false |
| 45 | Abzurdah | - | - | - | $3,842 | 175 | $4,771,660 | Jun 4 | Walt Disney Pictures | false |
| 46 | No Kids | - | - | - | $3,651 | 136 | $2,851,138 | May 14 | Walt Disney Pictures | false |
| 47 | The Vatican Tapes | - | - | - | $3,540 | 115 | $836,399 | Aug 6 | - | false |
| 48 | Spanish Affair | - | - | - | $3,314 | 18 | $313,251 | Jul 9 | Distribution Company | false |
| 49 | The 33 | - | - | - | $2,165 | 8 | $21,430 | Aug 27 | 20th Century Fox International | false |
| 50 | It Follows | - | - | - | $1,845 | 3 | $2,761 | Mar 26 | Impacto Cine | false |
| 51 | The Gallows | - | - | - | $1,830 | 91 | $2,160,289 | Jul 9 | Warner Bros. | false |
| 52 | Mission: Impossible - Rogue Nation | - | - | - | $1,485 | 214 | $3,158,317 | Jul 30 | United International Pictures | false |
| 53 | Terminator Genisys | - | - | - | $1,262 | 249 | $5,937,184 | Jul 9 | Paramount Pictures International | false |
| 54 | Trading Places in the Zoo | - | - | - | $1,072 | 134 | $759,399 | Jul 9 | Walt Disney Pictures | false |
| 55 | Vacation | - | - | - | $506 | 105 | $523,754 | Jul 30 | Warner Bros. | false |
| 56 | Guardians of Oz | - | - | - | $448 | 38 | $36,579 | Sep 10 | Impacto Cine | false |
| 57 | Mood Indigo | - | - | - | $443 | 6 | $5,630 | Sep 24 | Distribution Company | false |
| 58 | She's Funny That Way | - | - | - | $392 | 35 | $260,610 | Aug 27 | Distribution Company | false |
| 59 | Shaun the Sheep Movie | - | - | - | $334 | 142 | $314,956 | Sep 3 | United International Pictures | false |
| 60 | Fantastic Four | - | - | - | $293 | 158 | $1,425,574 | Aug 6 | 20th Century Fox International | false |
| 61 | The Man from U.N.C.L.E. | - | - | - | $143 | 108 | $368,127 | Aug 27 | Warner Bros. | false |
| 62 | Gloria | - | - | - | $76 | 7 | $7,480 | Sep 3 | Mirada Distribution | false |
| 63 | Kidnapping Mr. Heineken | - | - | - | $72 | 35 | $99,965 | Sep 17 | - | false |
| 64 | Southpaw | - | - | - | $47 | 97 | $242,708 | Aug 20 | - | false |
