| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Rise of the Planet of the Apes | - | - | - | $1,907,558 | 73 | $2,252,177 | Sep 30 | 20th Century Fox International | false |
| 2 | Transformers: Dark of the Moon | - | - | - | $1,744,351 | 103 | $2,618,374 | Oct 14 | - | false |
| 3 | Mr. Popper's Penguins | - | - | - | $1,464,106 | 62 | $3,122,579 | Sep 16 | 20th Century Fox International | false |
| 4 | Bad Teacher | - | - | - | $939,180 | 51 | $1,193,923 | Oct 7 | Sony Pictures Releasing | false |
| 5 | Fright Night | - | - | - | $603,724 | 58 | $634,361 | Sep 30 | Walt Disney Pictures | false |
| 6 | Sanctum | - | - | - | $435,609 | 42 | $456,600 | Oct 7 | - | false |
| 7 | The Rumble of the Stones | - | - | - | $399,890 | 24 | $604,565 | Sep 30 | - | false |
| 8 | Final Destination 5 | - | - | - | $369,985 | 69 | $2,455,391 | Oct 28 | Warner Bros. | false |
| 9 | Abduction | - | - | - | $361,578 | 30 | $625,974 | Sep 23 | - | false |
| 10 | Friends with Benefits | - | - | - | $349,684 | 51 | $1,531,724 | Sep 9 | Sony Pictures Releasing | false |
| 11 | Moneyball | - | - | - | $296,045 | 49 | $603,835 | Oct 21 | Sony Pictures Releasing | false |
| 12 | Er Conde Jones | - | - | - | $261,099 | 65 | $3,579,383 | Aug 26 | - | false |
| 13 | The Three Musketeers | - | - | - | $248,072 | 52 | $1,284,238 | Oct 28 | - | false |
| 14 | Something Borrowed | - | - | - | $170,685 | 15 | $330,015 | Oct 14 | - | false |
| 15 | Garfield's Pet Force | - | - | - | $137,411 | 31 | $471,031 | Sep 16 | - | false |
| 16 | Cars 2 | - | - | - | $89,032 | 116 | $4,570,943 | Aug 19 | Walt Disney Pictures | false |
| 17 | Green Lantern | - | - | - | $81,540 | 82 | $2,663,058 | Sep 2 | Warner Bros. | false |
| 18 | Hoodwinked Too! Hood vs. Evil | - | - | - | $71,526 | 18 | $96,540 | Sep 30 | - | false |
| 19 | Chinese Take-Away | - | - | - | $53,495 | 3 | $90,880 | Sep 24 | Walt Disney Pictures | false |
| 20 | Insidious | - | - | - | $43,786 | 20 | $346,607 | Sep 9 | - | false |
| 21 | Saluda al diablo de mi parte | - | - | - | $40,637 | 18 | $315,630 | Sep 9 | - | false |
| 22 | Barney's Version | - | - | - | $30,930 | 5 | $56,132 | Oct 21 | - | false |
| 23 | The Smurfs | - | - | - | $26,600 | 110 | $7,757,729 | Aug 5 | Sony Pictures Releasing | false |
| 24 | The Dilemma | - | - | - | $25,649 | 31 | $257,998 | Sep 16 | United International Pictures | false |
| 25 | Baaria | - | - | - | $16,707 | 3 | $43,666 | Oct 21 | - | false |
| 26 | Crazy, Stupid, Love. | - | - | - | $9,269 | 45 | $1,061,554 | Aug 19 | Warner Bros. | false |
| 27 | Igor | - | - | - | $2,764 | 22 | $56,582 | Sep 9 | - | false |
| 28 | Limitless | - | - | - | $2,643 | 27 | $627,863 | Aug 26 | - | false |
| 29 | Paul | - | - | - | $2,044 | 41 | $177,597 | Sep 2 | United International Pictures | false |
| 30 | You Will Meet a Tall Dark Stranger | - | - | - | $1,277 | 4 | $96,561 | Aug 12 | - | false |
| 31 | Zookeeper | - | - | - | $1,011 | 75 | $4,018,283 | Jul 22 | Sony Pictures Releasing | false |
| 32 | Horrible Bosses | - | - | - | $198 | 40 | $1,363,244 | Aug 5 | Warner Bros. | false |
| 33 | The Beaver | - | - | - | $184 | 15 | $184,980 | Aug 12 | - | false |
| 34 | Skyline | - | - | - | $180 | 15 | $151,722 | Aug 19 | - | false |
| 35 | Season of the Witch | - | - | - | $156 | 25 | $765,591 | Aug 12 | - | false |
