| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Eat Pray Love | - | - | - | $1,601,683 | 45 | $1,780,478 | Oct 2 | Sony Pictures Releasing | false |
| 2 | Red | - | - | - | $796,590 | 18 | $986,414 | Oct 16 | - | false |
| 3 | Detective Dee: The Mystery of the Phantom Flame | - | - | - | $666,364 | 19 | $759,625 | Oct 9 | Walt Disney Pictures | false |
| 4 | Life as We Know It | - | - | - | $346,550 | 17 | $557,333 | Oct 23 | Warner Bros. | false |
| 5 | The Town | - | - | - | $334,267 | 17 | $365,770 | Oct 2 | Warner Bros. | false |
| 6 | Resident Evil: Afterlife | - | - | - | $316,218 | 105 | $6,048,031 | Sep 10 | Sony Pictures Releasing | false |
| 7 | Wall Street: Money Never Sleeps | - | - | - | $311,180 | 17 | $833,306 | Sep 22 | 20th Century Fox International | false |
| 8 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $287,633 | 16 | $331,879 | Oct 9 | Warner Bros. | false |
| 9 | The Child's Eye | - | - | - | $238,345 | 18 | $285,700 | Oct 16 | - | false |
| 10 | Grown Ups | - | - | - | $230,439 | 33 | $252,773 | Oct 16 | Sony Pictures Releasing | false |
| 11 | Saw 3D | - | - | - | $193,019 | 19 | $695,862 | Oct 30 | - | false |
| 12 | Charlie St. Cloud | - | - | - | $96,896 | 18 | $107,745 | Oct 9 | United International Pictures | false |
| 13 | Reign of Assassins | - | - | - | $82,430 | 16 | $94,422 | Oct 23 | Long Shong Entertainment Multimedia Company | false |
| 14 | Legend of the Fist: The Return of Chen Zhen | - | - | - | $65,402 | 17 | $399,406 | Sep 25 | Long Shong Entertainment Multimedia Company | false |
| 15 | The Experiment 2010 Re-release | - | - | - | $61,072 | 11 | $69,393 | Oct 1 | - | false |
| 16 | Stone | - | - | - | $59,924 | 16 | $153,424 | Oct 30 | - | false |
| 17 | Let Me In | - | - | - | $57,635 | 13 | $65,487 | Oct 2 | - | false |
| 18 | Confessions | - | - | - | $53,218 | 7 | $765,676 | Oct 30 | - | false |
| 19 | The Human Centipede (First Sequence) | - | - | - | $50,419 | 12 | $61,108 | Oct 2 | - | false |
| 20 | Seven Days in Heaven | - | - | - | $49,619 | 13 | $572,292 | Aug 28 | - | false |
| 21 | Gintama: The Movie | - | - | - | $40,005 | 6 | $47,859 | Oct 16 | - | false |
| 22 | The Disappearance of Haruhi Suzumiya | - | - | - | $39,076 | 3 | $54,351 | Oct 23 | - | false |
| 23 | You Will Meet a Tall Dark Stranger | - | - | - | $25,822 | 9 | $29,557 | Oct 23 | - | false |
| 24 | Inception | - | - | - | $22,239 | 20 | $5,370,400 | Jul 17 | Warner Bros. | false |
| 25 | Mobile Suit Gundam 00: A Wakening of the Trailblazer | - | - | - | $19,257 | 1 | $59,715 | Oct 16 | - | false |
| 26 | Spring Fever | - | - | - | $14,427 | 2 | $16,971 | Oct 9 | - | false |
| 27 | Harmony | - | - | - | $9,663 | 5 | $13,187 | Oct 23 | - | false |
| 28 | Devil | - | - | - | $7,330 | 18 | $172,794 | Sep 18 | United International Pictures | false |
| 29 | The American | - | - | - | $5,924 | 12 | $172,954 | Sep 18 | - | false |
| 30 | Pope Joan | - | - | - | $5,875 | 2 | $6,159 | Oct 2 | - | false |
| 31 | Heartbreaker | - | - | - | $5,608 | 3 | $6,149 | Oct 23 | - | false |
| 32 | Going the Distance | - | - | - | $3,908 | 18 | $375,630 | Sep 4 | Warner Bros. | false |
| 33 | I Saw the Devil | - | - | - | $2,919 | 4 | $6,445 | Oct 30 | - | false |
| 34 | Tales of Vesperia: The First Strike 2010 Re-release | - | - | - | $2,692 | 2 | $4,351 | Oct 30 | - | false |
| 35 | Moss | - | - | - | $2,422 | 2 | $2,590 | Oct 23 | - | false |
| 36 | My Rainy Days | - | - | - | $2,374 | 1 | $2,598 | Oct 23 | - | false |
| 37 | Dancing Dreams | - | - | - | $1,878 | 1 | $9,682 | Sep 18 | - | false |
| 38 | Parêdo | - | - | - | $1,632 | 1 | $1,788 | Oct 30 | - | false |
| 39 | Krai... Nai Hong | - | - | - | $1,526 | 10 | $49,891 | Sep 25 | - | false |
| 40 | Lourdes | - | - | - | $1,414 | 1 | $1,556 | Oct 16 | - | false |
| 41 | Goodbye, Someday | - | - | - | $1,307 | 11 | $50,517 | Sep 11 | - | false |
| 42 | Box! | - | - | - | $998 | 6 | $1,302 | Oct 9 | - | false |
| 43 | Greenberg | - | - | - | $957 | 5 | $13,183 | Sep 25 | - | false |
| 44 | Bangkok Traffic (Love) Story | - | - | - | $765 | 4 | $23,288 | Sep 11 | - | false |
| 45 | The Girl Who Played with Fire | - | - | - | $525 | 11 | $42,030 | Sep 18 | - | false |
| 46 | Step Up 3D | - | - | - | $430 | 18 | $1,891,029 | Aug 14 | - | false |
| 47 | Man of Vendetta | - | - | - | $382 | 2 | $1,707 | Sep 25 | - | false |
| 48 | Ocean Heaven | - | - | - | $236 | 11 | $226,948 | Aug 27 | - | false |
| 49 | Flowers | - | - | - | $120 | 9 | $9,978 | Sep 11 | - | false |
