| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Enthiran | - | - | - | $2,935,124 | 80 | $3,048,246 | Sep 30 | Five Star | false |
| 2 | The Child's Eye | - | - | - | $1,329,811 | 82 | $1,487,116 | Oct 14 | - | false |
| 3 | Detective Dee: The Mystery of the Phantom Flame | - | - | - | $887,808 | 62 | $887,808 | Sep 30 | - | false |
| 4 | Legend of the Fist: The Return of Chen Zhen | - | - | - | $868,667 | 97 | $2,049,033 | Sep 23 | Golden Screen Cinemas | false |
| 5 | The Other Guys | - | - | - | $792,360 | 43 | $880,971 | Oct 14 | Sony Pictures Releasing | false |
| 6 | A Turtle's Tale: Sammy's Adventures | - | - | - | $718,161 | 81 | $742,057 | Oct 7 | Golden Screen Cinemas | false |
| 7 | Magika | - | - | - | $630,771 | 64 | $1,041,237 | Sep 23 | - | false |
| 8 | Eat Pray Love | - | - | - | $435,760 | 25 | $440,613 | Sep 30 | Sony Pictures Releasing | false |
| 9 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $392,199 | 85 | $807,586 | Sep 23 | Warner Bros. | false |
| 10 | Reign of Assassins | - | - | - | $387,099 | 44 | $409,988 | Oct 14 | Golden Screen Cinemas | false |
| 11 | The Extraordinary Adventures of Adèle Blanc-Sec | - | - | - | $336,496 | 50 | $920,652 | Oct 28 | - | false |
| 12 | Takers 2010 Re-release | - | - | - | $324,076 | 52 | $957,802 | Oct 28 | Sony Pictures Releasing | false |
| 13 | Life as We Know It | - | - | - | $284,974 | 28 | $443,749 | Oct 21 | Warner Bros. | false |
| 14 | Wall Street: Money Never Sleeps | - | - | - | $205,240 | 35 | $434,317 | Sep 23 | 20th Century Fox International | false |
| 15 | You Again | - | - | - | $202,651 | 32 | $328,739 | Oct 21 | Walt Disney Pictures | false |
| 16 | Buried | - | - | - | $197,179 | 30 | $197,179 | Oct 14 | - | false |
| 17 | Red | - | - | - | $187,296 | 58 | $903,153 | Oct 21 | Golden Screen Cinemas | false |
| 18 | The American | - | - | - | $164,654 | 17 | $164,654 | Oct 7 | - | false |
| 19 | Resident Evil: Afterlife | - | - | - | $154,383 | 139 | $3,563,274 | Sep 10 | Sony Pictures Releasing | false |
| 20 | Charlie St. Cloud | - | - | - | $151,399 | 15 | $163,181 | Sep 30 | United International Pictures | false |
| 21 | The Switch | - | - | - | $137,033 | 20 | $137,033 | Oct 7 | - | false |
| 22 | Dinner for Schmucks | - | - | - | $135,527 | 15 | $135,527 | Oct 7 | United International Pictures | false |
| 23 | Alpha and Omega | - | - | - | $128,728 | 33 | $128,728 | Sep 30 | - | false |
| 24 | Devil | - | - | - | $77,236 | 42 | $555,731 | Sep 16 | United International Pictures | false |
| 25 | Blood Ties 2010 Re-release | - | - | - | $76,113 | 18 | $76,113 | Sep 30 | - | false |
| 26 | The Hole | - | - | - | $64,552 | 19 | $139,937 | Sep 23 | - | false |
| 27 | The Sanctuary 2010 Re-release | - | - | - | $29,203 | 24 | $29,203 | Oct 14 | - | false |
| 28 | Anjaana Anjaani | - | - | - | $26,166 | 2 | $26,166 | Sep 30 | Five Star | false |
| 29 | Piranha 3D | - | - | - | $19,220 | 66 | $2,120,514 | Sep 2 | - | false |
| 30 | Hachi: A Dog's Tale | - | - | - | $18,281 | 3 | $48,045 | Oct 21 | Golden Screen Cinemas | false |
| 31 | Love Cuts | - | - | - | $9,625 | 25 | $26,252 | Oct 28 | - | false |
| 32 | Ocean Heaven | - | - | - | $6,482 | 8 | $16,155 | Oct 28 | - | false |
| 33 | Step Up 3D | - | - | - | $5,444 | 70 | $1,503,391 | Aug 26 | - | false |
| 34 | Grown Ups | - | - | - | $5,110 | 45 | $770,022 | Aug 26 | Sony Pictures Releasing | false |
| 35 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $4,545 | 69 | $721,521 | Sep 2 | Warner Bros. | false |
| 36 | Toy Story 3 | - | - | - | $3,596 | 108 | $2,812,540 | Jun 17 | Walt Disney Pictures | false |
| 37 | Repo Men | - | - | - | $3,503 | 25 | $214,627 | Aug 19 | United International Pictures | false |
| 38 | Avatar 2010 Special Edition | - | - | - | $3,496 | 29 | $381,873 | Aug 26 | 20th Century Fox International | false |
| 39 | The Descent: Part 2 | - | - | - | $3,281 | 40 | $246,222 | Aug 19 | Sony Pictures Releasing | false |
| 40 | Vampires Suck | - | - | - | $1,304 | 45 | $511,600 | Aug 26 | 20th Century Fox International | false |
| 41 | Boss Engira Baskaran | - | - | - | $673 | 17 | $289,672 | Sep 9 | Five Star | false |
| 42 | Going the Distance | - | - | - | $533 | 25 | $186,161 | Sep 2 | Warner Bros. | false |
| 43 | Old Cow Vs Tender Grass | - | - | - | $255 | 64 | $445,888 | Sep 2 | - | false |
| 44 | The Back-up Plan | - | - | - | $247 | 35 | $287,964 | Jul 1 | Sony Pictures Releasing | false |
| 45 | Salt | - | - | - | $155 | 110 | $2,634,070 | Jul 29 | Sony Pictures Releasing | false |
