| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Cloudy with a Chance of Meatballs | - | - | - | $1,586,844 | 63 | $2,287,269 | Oct 9 | Sony Pictures Releasing | false |
| 2 | Surrogates | - | - | - | $1,476,648 | 45 | $1,637,609 | Oct 2 | Walt Disney Pictures | false |
| 3 | The Ugly Truth | - | - | - | $991,915 | 36 | $2,010,193 | Sep 18 | Sony Pictures Releasing | false |
| 4 | Venezzia | - | - | - | $715,134 | 29 | $1,302,931 | Sep 25 | - | false |
| 5 | The Taking of Pelham 123 | - | - | - | $607,222 | 52 | $2,100,185 | Sep 11 | Sony Pictures Releasing | false |
| 6 | Inglourious Basterds | - | - | - | $532,228 | 34 | $855,911 | Oct 9 | United International Pictures | false |
| 7 | District 9 | - | - | - | $467,090 | 30 | $728,302 | Oct 16 | Sony Pictures Releasing | false |
| 8 | Saw VI | - | - | - | $457,573 | 40 | $2,024,684 | Oct 23 | Walt Disney Pictures | false |
| 9 | Orphan | - | - | - | $363,342 | 45 | $2,096,667 | Sep 4 | Warner Bros. | false |
| 10 | The Dolphin: Story of a Dreamer | - | - | - | $341,659 | 30 | $495,092 | Oct 9 | 20th Century Fox International | false |
| 11 | The Uninvited | - | - | - | $312,985 | 29 | $500,110 | Oct 16 | United International Pictures | false |
| 12 | Whiteout | - | - | - | $270,407 | 39 | $540,207 | Oct 23 | Warner Bros. | false |
| 13 | Ghosts of Girlfriends Past | - | - | - | $252,146 | 22 | $968,933 | Sep 4 | - | false |
| 14 | Land of the Lost | - | - | - | $248,189 | 41 | $862,222 | Oct 23 | United International Pictures | false |
| 15 | Boogeyman 2 | - | - | - | $226,535 | 12 | $232,094 | Oct 2 | - | false |
| 16 | Aliens in the Attic | - | - | - | $213,545 | 50 | $1,919,023 | Aug 28 | 20th Century Fox International | false |
| 17 | The Hangover | - | - | - | $187,898 | 58 | $2,605,296 | Aug 28 | Warner Bros. | false |
| 18 | The Proposal | - | - | - | $144,203 | 41 | $2,636,592 | Aug 14 | Walt Disney Pictures | false |
| 19 | Día naranja | - | - | - | $124,085 | 23 | $166,739 | Oct 16 | - | false |
| 20 | 12 Rounds | - | - | - | $113,917 | 19 | $251,580 | Sep 25 | 20th Century Fox International | false |
| 21 | Broken Embraces | - | - | - | $105,323 | 12 | $164,798 | Oct 16 | United International Pictures | false |
| 22 | School for Scoundrels 2009 Re-release | - | - | - | $89,219 | 14 | $340,189 | Sep 4 | - | false |
| 23 | Tinker Bell and the Lost Treasure | - | - | - | $85,061 | 22 | $438,225 | Sep 4 | Walt Disney Pictures | false |
| 24 | See No Evil 2009 Re-release | - | - | - | $83,782 | 7 | $143,499 | Sep 18 | - | false |
| 25 | Unknown 2009 Re-release | - | - | - | $81,228 | 15 | $81,228 | Oct 2 | - | false |
| 26 | I Do: How to Get Married and Stay Single 2009 Re-release | - | - | - | $70,733 | 5 | $121,080 | Sep 25 | - | false |
| 27 | Zomora | - | - | - | $48,146 | 19 | $48,146 | Oct 2 | - | false |
| 28 | G-Force | - | - | - | $47,874 | 58 | $5,183,475 | Jul 31 | Walt Disney Pictures | false |
| 29 | Imagine That | - | - | - | $47,339 | 48 | $1,230,179 | Aug 21 | United International Pictures | false |
| 30 | Then She Found Me | - | - | - | $40,565 | 9 | $46,048 | Oct 23 | - | false |
| 31 | Hannah Montana: The Movie | - | - | - | $21,236 | 30 | $534,271 | Aug 28 | Walt Disney Pictures | false |
| 32 | Cassandra's Dream | - | - | - | $18,489 | 7 | $106,659 | Sep 18 | - | false |
| 33 | Donkey Xote | - | - | - | $9,625 | 20 | $133,093 | Aug 21 | - | false |
| 34 | Jonas Brothers: The 3D Concert Experience | - | - | - | $5,875 | 3 | $48,520 | Sep 18 | Walt Disney Pictures | false |
| 35 | The Bank Job | - | - | - | $4,187 | 19 | $575,540 | Aug 14 | - | false |
| 36 | Shorts | - | - | - | $3,300 | 49 | $1,041,526 | Aug 14 | Warner Bros. | false |
| 37 | Vinotinto - La película | - | - | - | $2,825 | 16 | $156,931 | Aug 28 | - | false |
| 38 | Public Enemies | - | - | - | $2,541 | 47 | $875,234 | Aug 21 | United International Pictures | false |
| 39 | Fighting | - | - | - | $2,004 | 20 | $232,319 | Sep 4 | United International Pictures | false |
| 40 | Two Days in Paris | - | - | - | $805 | 5 | $71,157 | Oct 2 | - | false |
