| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Secret in Their Eyes | - | - | - | $2,099,909 | 90 | $9,255,067 | Aug 13 | Distribution Company | false |
| 2 | Cloudy with a Chance of Meatballs | - | - | - | $1,247,080 | 71 | $1,667,186 | Oct 1 | Sony Pictures Releasing | false |
| 3 | The Final Destination | - | - | - | $644,468 | 71 | $1,733,271 | Sep 17 | Distribution Company | false |
| 4 | The Widows of Thursdays | - | - | - | $582,614 | 80 | $1,999,017 | Sep 10 | Alfa Films | false |
| 5 | Broken Embraces | - | - | - | $465,068 | 35 | $515,741 | Oct 1 | Universal Pictures International (UPI) | false |
| 6 | Surrogates | - | - | - | $405,539 | 49 | $826,572 | Oct 22 | Walt Disney Pictures | false |
| 7 | Orphan | - | - | - | $372,716 | 38 | $610,784 | Sep 24 | Warner Bros. | false |
| 8 | District 9 | - | - | - | $341,062 | 45 | $554,342 | Sep 24 | Sony Pictures Releasing | false |
| 9 | A Matter of Principles | - | - | - | $326,975 | 36 | $581,219 | Sep 24 | - | false |
| 10 | My Life in Ruins | - | - | - | $300,549 | 40 | $396,055 | Oct 8 | Distribution Company | false |
| 11 | Inglourious Basterds | - | - | - | $289,369 | 56 | $1,216,394 | Sep 3 | Universal Pictures International (UPI) | false |
| 12 | Boogie | - | - | - | $277,203 | 51 | $406,610 | Oct 22 | Distribution Company | false |
| 13 | This Is It | - | - | - | $256,454 | 82 | $647,258 | Oct 29 | Sony Pictures Releasing | false |
| 14 | Jennifer's Body | - | - | - | $165,751 | 27 | $195,110 | Oct 1 | 20th Century Fox International | false |
| 15 | Julie & Julia | - | - | - | $140,727 | 40 | $430,607 | Sep 17 | Sony Pictures Releasing | false |
| 16 | Night Runner | - | - | - | $110,510 | 52 | $338,898 | Oct 29 | Alfa Films | false |
| 17 | Welcome to the Sticks | - | - | - | $104,552 | 21 | $155,242 | Oct 15 | Distribution Company | false |
| 18 | [Rec]² | - | - | - | $103,513 | 27 | $303,775 | Oct 29 | CDI Films | false |
| 19 | Dad for a Day | - | - | - | $95,405 | 75 | $1,770,291 | Aug 6 | Walt Disney Pictures | false |
| 20 | The Ugly Truth | - | - | - | $94,139 | 31 | $528,566 | Aug 27 | Sony Pictures Releasing | false |
| 21 | The Dolphin: Story of a Dreamer | - | - | - | $88,936 | 21 | $151,480 | Oct 8 | 20th Century Fox International | false |
| 22 | Tinker Bell and the Lost Treasure | - | - | - | $87,519 | 49 | $553,375 | Sep 3 | Walt Disney Pictures | false |
| 23 | The Brothers Bloom | - | - | - | $79,230 | 17 | $151,151 | Oct 22 | Alfa Films | false |
| 24 | Everyone Else | - | - | - | $75,167 | 10 | $93,317 | Oct 15 | IFA | false |
| 25 | Shorts | - | - | - | $68,347 | 21 | $245,752 | Sep 10 | Warner Bros. | false |
| 26 | The Time Traveler's Wife | - | - | - | $64,690 | 30 | $128,974 | Sep 24 | Distribution Company | false |
| 27 | My Best Friend's Girl | - | - | - | $38,445 | 25 | $99,311 | Sep 17 | Alfa Films | false |
| 28 | The Soloist | - | - | - | $37,045 | 16 | $138,291 | Oct 29 | Paramount Pictures International | false |
| 29 | Cherry Blossoms | - | - | - | $36,042 | 6 | $73,095 | Sep 17 | Alfa Films | false |
| 30 | The Killing Gene | - | - | - | $35,871 | 9 | $39,077 | Oct 15 | CDI Films | false |
| 31 | Lemon Tree | - | - | - | $35,643 | 11 | $117,698 | Oct 29 | Distribution Company | false |
| 32 | Anita | - | - | - | $31,669 | 47 | $404,609 | Aug 27 | Distribution Company | false |
| 33 | The Meerkats | - | - | - | $28,955 | 34 | $35,101 | Oct 8 | Alfa Films | false |
| 34 | The Hangover | - | - | - | $27,864 | 42 | $855,892 | Aug 13 | Warner Bros. | false |
| 35 | G-Force | - | - | - | $24,618 | 116 | $2,110,560 | Jul 30 | Walt Disney Pictures | false |
| 36 | Aliens in the Attic | - | - | - | $22,458 | 32 | $200,004 | Aug 20 | 20th Century Fox International | false |
| 37 | The Haunting in Connecticut | - | - | - | $22,264 | 24 | $208,676 | Aug 20 | Alfa Films | false |
| 38 | Coco Before Chanel | - | - | - | $17,174 | 17 | $219,920 | Aug 27 | Warner Bros. | false |
| 39 | Pandora's Box | - | - | - | $15,828 | 6 | $19,182 | Oct 22 | Primer Plano Film Group | false |
| 40 | Horizontal/Vertical | - | - | - | $14,104 | 13 | $14,104 | Oct 22 | Primer Plano Film Group | false |
| 41 | Ashes of Time | - | - | - | $10,956 | 5 | $12,565 | Oct 8 | Distribution Company | false |
| 42 | Traitor | - | - | - | $9,909 | 20 | $67,295 | Sep 10 | Distribution Company | false |
| 43 | My Bloody Valentine | - | - | - | $7,943 | 60 | $574,286 | Sep 3 | Alfa Films | false |
| 44 | Homero Manzi, un poeta en la tormenta | - | - | - | $7,439 | 5 | $14,857 | Sep 24 | Primer Plano Film Group | false |
| 45 | The Wave | - | - | - | $7,257 | 18 | $181,293 | Aug 20 | Impacto Cine | false |
| 46 | Ice Age: Dawn of the Dinosaurs | - | - | - | $7,005 | 170 | $8,069,767 | Jul 2 | 20th Century Fox International | false |
| 47 | Nunca estuviste tan adorable | - | - | - | $6,075 | 5 | $7,299 | Oct 8 | Primer Plano Film Group | false |
| 48 | Street Fighter: The Legend of Chun-Li | - | - | - | $5,788 | 5 | $5,788 | Oct 1 | Distribution Company | false |
| 49 | Tierra sublevada: Oro impuro | - | - | - | $4,819 | 6 | $16,933 | Sep 10 | Primer Plano Film Group | false |
| 50 | Wrong Rosary | - | - | - | $4,801 | 4 | $9,767 | Oct 29 | - | false |
| 51 | Hannah Montana: The Movie | - | - | - | $4,711 | 68 | $458,212 | Aug 13 | Walt Disney Pictures | false |
| 52 | Giovanna's Father 2009 Re-release | - | - | - | $2,863 | 5 | $9,129 | Sep 24 | Primer Plano Film Group | false |
| 53 | Drag Me to Hell | - | - | - | $2,501 | 36 | $450,226 | Aug 13 | Universal Pictures International (UPI) | false |
| 54 | Stranded | - | - | - | $2,491 | 5 | $2,491 | Oct 15 | - | false |
| 55 | Wild Blood | - | - | - | $2,442 | 9 | $23,353 | Sep 3 | Pachamama Cine | false |
| 56 | The Secret of the Grain | - | - | - | $1,335 | 7 | $83,642 | Jul 30 | - | false |
| 57 | G.I. Joe: The Rise of Cobra | - | - | - | $1,172 | 67 | $451,933 | Aug 6 | Paramount Pictures International | false |
| 58 | Mentiras piadosas | - | - | - | $1,086 | 6 | $20,176 | Aug 20 | - | false |
| 59 | El hombre que corría tras el viento | - | - | - | $924 | 26 | $36,014 | Sep 3 | Primer Plano Film Group | false |
| 60 | The Age of Stupid | - | - | - | $881 | 2 | $3,072 | Sep 24 | - | false |
| 61 | Unidad 25 | - | - | - | $607 | 1 | $633 | Oct 15 | - | false |
| 62 | Defiance | - | - | - | $327 | 29 | $120,141 | Aug 6 | - | false |
| 63 | The Dress | - | - | - | $270 | 5 | $5,948 | Sep 17 | Primer Plano Film Group | false |
| 64 | Harry Potter and the Half-Blood Prince | - | - | - | $244 | 143 | $4,461,626 | Jul 23 | Warner Bros. | false |
| 65 | Transformers: Revenge of the Fallen | - | - | - | $233 | 119 | $2,491,004 | Jun 25 | Paramount Pictures International | false |
| 66 | Breath 2009 Re-release | - | - | - | $175 | 9 | $20,563 | Jul 30 | Distribution Company | false |
| 67 | A Christmas Tale | - | - | - | $62 | 11 | $90,076 | Jul 2 | Pachamama Cine | false |
| 68 | Inspector Bellamy | - | - | - | $52 | 14 | $140,116 | Jun 4 | Alfa Films | false |
| 69 | The Reader | - | - | - | $42 | 35 | $570,036 | May 7 | Pachamama Cine | false |
