| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Devil Wears Prada | - | - | - | $708,378 | 70 | $1,313,141 | Oct 19 | 20th Century Fox International | false |
| 2 | Step Up | - | - | - | $573,221 | 42 | $832,024 | Sep 28 | United International Pictures | false |
| 3 | Garfield: A Tail of Two Kitties | - | - | - | $563,355 | 80 | $1,317,424 | Sep 14 | 20th Century Fox International | false |
| 4 | Out of the Blue | - | - | - | $405,360 | 36 | $723,690 | Oct 12 | Dendy Films | false |
| 5 | Gridiron Gang | - | - | - | $356,366 | 46 | $412,125 | Oct 12 | Sony Pictures Releasing | false |
| 6 | The Wild | - | - | - | $301,991 | 41 | $552,213 | Sep 21 | Buena Vista International | false |
| 7 | Little Miss Sunshine | - | - | - | $290,888 | 27 | $838,132 | Oct 12 | 20th Century Fox International | false |
| 8 | World Trade Center | - | - | - | $276,628 | 44 | $291,837 | Oct 5 | United International Pictures | false |
| 9 | Barnyard | - | - | - | $253,387 | 50 | $457,401 | Sep 21 | United International Pictures | false |
| 10 | Monster House | - | - | - | $241,967 | 64 | $542,098 | Sep 21 | Sony Pictures Releasing | false |
| 11 | An Inconvenient Truth | - | - | - | $231,069 | 23 | $680,559 | Sep 14 | United International Pictures | false |
| 12 | The Guardian | - | - | - | $207,025 | 41 | $314,957 | Oct 19 | Buena Vista International | false |
| 13 | Mrs Palfrey at the Claremont | - | - | - | $199,953 | 41 | $1,156,523 | Aug 17 | Rialto Distribution | false |
| 14 | Stormbreaker | - | - | - | $185,734 | 46 | $416,113 | Sep 21 | Roadshow Films | false |
| 15 | Talladega Nights: The Ballad of Ricky Bobby | - | - | - | $164,806 | 53 | $471,704 | Sep 21 | Sony Pictures Releasing | false |
| 16 | John Tucker Must Die | - | - | - | $146,593 | 35 | $394,795 | Sep 21 | 20th Century Fox International | false |
| 17 | Wah-Wah | - | - | - | $135,689 | 28 | $377,206 | Sep 7 | Hopscotch Films | false |
| 18 | Nacho Libre | - | - | - | $133,724 | 51 | $556,830 | Sep 14 | United International Pictures | false |
| 19 | The Grudge 2 | - | - | - | $113,738 | 32 | $340,523 | Oct 26 | Roadshow Films | false |
| 20 | Water 2006 Re-release | - | - | - | $112,939 | 16 | $236,534 | Sep 21 | Dendy Films | false |
| 21 | Stick It | - | - | - | $108,525 | 31 | $429,657 | Sep 14 | Roadshow Films | false |
| 22 | Brick | - | - | - | $88,060 | 23 | $108,546 | Oct 5 | Rialto Distribution | false |
| 23 | The Ant Bully | - | - | - | $75,713 | 50 | $150,527 | Sep 21 | Warner Bros. | false |
| 24 | Tristram Shandy | - | - | - | $45,595 | 4 | $64,418 | Oct 5 | Madman Entertainment | false |
| 25 | Don | - | - | - | $39,532 | 5 | $52,556 | Oct 19 | MG Distribution | false |
| 26 | Friends with Money | - | - | - | $25,093 | 10 | $90,981 | Oct 26 | Roadshow Films | false |
| 27 | The Wind that Shakes the Barley | - | - | - | $21,171 | 21 | $207,528 | Oct 26 | Dendy Films | false |
| 28 | Thank You for Smoking | - | - | - | $20,758 | 10 | $312,695 | Aug 24 | 20th Century Fox International | false |
| 29 | Fast Food Nation | - | - | - | $19,946 | 19 | $36,685 | Oct 26 | Dendy Films | false |
| 30 | Junebug | - | - | - | $12,042 | 17 | $21,952 | Oct 19 | Arkles Entertainment | false |
