| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Fantastic Beasts and Where to Find Them | - | - | - | $12,250,419 | 783 | $16,200,000 | Nov 17 | Warner Bros. | false |
| 2 | Doctor Strange | - | - | - | $5,381,651 | 578 | $8,194,378 | Oct 26 | Walt Disney Pictures | false |
| 3 | The Girl on the Train | - | - | - | $5,228,331 | 467 | $5,380,555 | Nov 3 | Leone Film Group | false |
| 4 | Trolls | - | - | - | $3,885,046 | 511 | $4,911,414 | Oct 27 | 20th Century Fox International | false |
| 5 | At War with Love | - | - | - | $2,928,810 | 507 | $3,916,517 | Oct 27 | 01 Distribution | false |
| 6 | Inferno | - | - | - | $2,498,116 | 749 | $13,938,143 | Oct 13 | Sony Pictures Releasing | false |
| 7 | Masterminds | - | - | - | $2,437,183 | 262 | $2,643,130 | Nov 10 | Lucky Red | false |
| 8 | Non si ruba a casa dei ladri | - | - | - | $2,359,147 | 320 | $2,359,147 | Nov 3 | Medusa Distribuzione | false |
| 9 | Ouija: Origin of Evil | - | - | - | $1,868,085 | 242 | $2,675,728 | Oct 27 | Universal Pictures International (UPI) | false |
| 10 | Nocturnal Animals | - | - | - | $1,731,057 | 287 | $2,241,355 | Nov 17 | Universal Pictures International (UPI) | false |
| 11 | The Secret Life of Pets | - | - | - | $1,712,259 | 565 | $14,810,477 | Oct 6 | Universal Pictures International (UPI) | false |
| 12 | Che vuoi che sia | - | - | - | $1,542,328 | 400 | $1,728,588 | Nov 10 | Warner Bros. | false |
| 13 | La cena di Natale | - | - | - | $1,345,293 | 424 | $2,236,363 | Nov 24 | 01 Distribution | false |
| 14 | Quel bravo ragazzo | - | - | - | $1,306,628 | 292 | $1,365,822 | Nov 17 | Mediafilm | false |
| 15 | Sweet Dreams | - | - | - | $1,263,728 | 238 | $1,263,728 | Nov 10 | 01 Distribution | false |
| 16 | How to Grow Up Despite Your Parents | - | - | - | $1,184,775 | 374 | $2,038,275 | Nov 24 | Walt Disney Pictures | false |
| 17 | The Accountant | - | - | - | $1,134,225 | 302 | $1,800,000 | Oct 27 | Warner Bros. | false |
| 18 | Sausage Party | - | - | - | $1,043,249 | 200 | $1,043,249 | Nov 3 | Sony Pictures Releasing | false |
| 19 | Snowden | - | - | - | $949,596 | 272 | $1,699,527 | Nov 24 | BIM Distribuzione | false |
| 20 | Mechanic: Resurrection | - | - | - | $789,928 | 205 | $1,221,501 | Nov 24 | Eagle Pictures | false |
| 21 | Genius | - | - | - | $780,176 | 231 | $899,000 | Nov 10 | Eagle Pictures | false |
| 22 | A Street Cat Named Bob | - | - | - | $773,015 | 189 | $1,096,723 | Nov 10 | Notorious Pictures | false |
| 23 | I, Daniel Blake | - | - | - | $641,762 | 116 | $1,412,911 | Oct 20 | - | false |
| 24 | Kubo and the Two Strings | - | - | - | $594,188 | 273 | $631,007 | Nov 3 | Universal Pictures International (UPI) | false |
| 25 | 7 Minutes | - | - | - | $593,966 | 214 | $593,966 | Nov 3 | Koch Media | false |
| 26 | Storks | - | - | - | $370,358 | 345 | $1,413,945 | Oct 20 | Warner Bros. | false |
| 27 | Sing Street | - | - | - | $348,260 | 65 | $418,739 | Nov 10 | BIM Distribuzione | false |
| 28 | Jack Reacher: Never Go Back | - | - | - | $321,759 | 307 | $2,059,766 | Oct 20 | Paramount Pictures International | false |
| 29 | One Piece Film: Gold | - | - | - | $317,578 | 141 | $385,312 | Nov 24 | Koch Media | false |
| 30 | Snowtime! | - | - | - | $270,572 | 280 | $352,867 | Nov 24 | Notorious Pictures | false |
| 31 | I babysitter | - | - | - | $225,622 | 344 | $1,515,576 | Oct 20 | Medusa Distribuzione | false |
| 32 | Something New | - | - | - | $206,676 | 396 | $2,255,165 | Oct 13 | 01 Distribution | false |
| 33 | The Unknown Girl | - | - | - | $206,497 | 73 | $319,391 | Oct 27 | BIM Distribuzione | false |
| 34 | American Pastoral | - | - | - | $181,478 | 190 | $817,402 | Oct 20 | Eagle Pictures | false |
| 35 | The Innocents | - | - | - | $146,231 | 56 | $208,211 | Nov 24 | Good Films | false |
| 36 | Sheep & Wolves | - | - | - | $135,260 | 214 | $135,260 | Nov 17 | Barter Films | false |
| 37 | 3 Generations | - | - | - | $124,673 | 98 | $210,917 | Nov 24 | Videa | false |
| 38 | Finding Dory | - | - | - | $117,529 | 800 | $17,433,399 | Sep 15 | Walt Disney Pictures | false |
| 39 | Denial | - | - | - | $107,415 | 72 | $107,415 | Nov 17 | - | false |
| 40 | Lamb of God 2016 Re-release | - | - | - | $97,956 | 60 | $116,744 | Nov 17 | Good Films | false |
| 41 | La pelle dell'orso | - | - | - | $82,653 | 27 | $98,890 | Nov 3 | Parthenos | false |
| 42 | The Forger 2016 Re-release | - | - | - | $65,987 | 44 | $65,987 | Nov 24 | M2 Pictures | false |
| 43 | Southside with You | - | - | - | $65,590 | 103 | $220,701 | Nov 17 | Microcinema | false |
| 44 | Café Society | - | - | - | $40,139 | 420 | $4,034,370 | Sep 29 | Warner Bros. | false |
| 45 | Pete's Dragon | - | - | - | $10,098 | 512 | $4,210,372 | Aug 10 | Walt Disney Pictures | false |
| 46 | Julieta | - | - | - | $6,533 | 315 | $2,476,404 | May 26 | Warner Bros. | false |
| 47 | Zootopia | - | - | - | $3,443 | 615 | $12,643,572 | Feb 18 | Walt Disney Pictures | false |
| 48 | Deepwater Horizon | - | - | - | $3,216 | 290 | $1,058,198 | Oct 6 | Leone Film Group | false |
| 49 | The Jungle Book | - | - | - | $1,344 | 766 | $11,956,478 | Apr 14 | Walt Disney Pictures | false |
| 50 | The Man Who Knew Infinity | - | - | - | $556 | 223 | $1,200,726 | Jun 9 | Eagle Pictures | false |
| 51 | Alice Through the Looking Glass | - | - | - | $318 | 726 | $7,374,314 | May 25 | Walt Disney Pictures | false |
