| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $17,507,830 | 836 | $24,923,463 | Nov 19 | Warner Bros. | false |
| 2 | Men Vs Women | - | - | - | $12,389,153 | 575 | $18,452,860 | Oct 27 | 01 Distribution | false |
| 3 | Welcome to the South | - | - | - | $5,534,507 | 568 | $43,015,634 | Oct 1 | Medusa Distribuzione | false |
| 4 | Saw 3D | - | - | - | $4,922,775 | 275 | $7,037,160 | Nov 17 | Moviemax | false |
| 5 | Despicable Me | - | - | - | $4,051,067 | 544 | $17,064,781 | Oct 15 | United International Pictures | false |
| 6 | A Natale mi sposo | - | - | - | $3,211,632 | 450 | $10,583,880 | Nov 26 | Medusa Distribuzione | false |
| 7 | Winx Club 3D: Magical Adventure | - | - | - | $3,086,354 | 382 | $3,872,632 | Oct 29 | Medusa Distribuzione | false |
| 8 | The Social Network | - | - | - | $2,841,337 | 311 | $3,758,965 | Nov 12 | Sony Pictures Releasing | false |
| 9 | Tangled | - | - | - | $2,465,536 | 584 | $14,670,362 | Nov 26 | Walt Disney Pictures | false |
| 10 | Ti presento un amico | - | - | - | $2,365,532 | 385 | $2,433,357 | Nov 12 | Warner Bros. | false |
| 11 | Salt | - | - | - | $2,039,069 | 297 | $3,187,250 | Oct 29 | Sony Pictures Releasing | false |
| 12 | Everybody's Fine | - | - | - | $1,893,570 | 227 | $1,994,220 | Nov 12 | Medusa Distribuzione | false |
| 13 | A Quiet Life | - | - | - | $1,657,124 | 164 | $2,021,470 | Nov 5 | 01 Distribution | false |
| 14 | Unstoppable | - | - | - | $1,642,573 | 251 | $1,683,466 | Nov 12 | 20th Century Fox International | false |
| 15 | Devil | - | - | - | $1,635,682 | 194 | $1,676,907 | Nov 12 | United International Pictures | false |
| 16 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $1,547,407 | 298 | $2,177,011 | Oct 29 | Warner Bros. | false |
| 17 | Last Night | - | - | - | $1,517,431 | 238 | $1,517,431 | Nov 5 | Medusa Distribuzione | false |
| 18 | The Switch | - | - | - | $1,308,026 | 186 | $1,499,653 | Nov 5 | Moviemax | false |
| 19 | The Worst Week of My Life | - | - | - | $1,278,518 | 291 | $3,825,937 | Nov 26 | Universal Pictures International (UPI) | false |
| 20 | Wall Street: Money Never Sleeps | - | - | - | $1,184,398 | 324 | $4,137,171 | Oct 22 | 20th Century Fox International | false |
| 21 | The Accidental Husband | - | - | - | $1,099,020 | 193 | $1,213,842 | Nov 19 | Eagle Pictures | false |
| 22 | Paranormal Activity 2 | - | - | - | $993,669 | 250 | $3,856,430 | Oct 22 | United International Pictures | false |
| 23 | We Believed | - | - | - | $972,489 | 77 | $2,124,145 | Nov 12 | 01 Distribution | false |
| 24 | Potiche | - | - | - | $969,523 | 103 | $1,051,787 | Nov 5 | BIM Distribuzione | false |
| 25 | 22 Bullets | - | - | - | $960,840 | 173 | $1,007,452 | Nov 5 | Eagle Pictures | false |
| 26 | Of Gods and Men | - | - | - | $837,010 | 65 | $1,891,721 | Oct 22 | Lucky Red | false |
| 27 | Unlikely Revolutionaries | - | - | - | $470,183 | 265 | $2,104,909 | Oct 22 | Warner Bros. | false |
| 28 | Step Up 3D | - | - | - | $464,716 | 339 | $9,282,511 | Oct 8 | Eagle Pictures | false |
| 29 | Scott Pilgrim vs. the World | - | - | - | $298,363 | 99 | $298,363 | Nov 19 | United International Pictures | false |
| 30 | Porco Rosso 2010 Re-release | - | - | - | $272,183 | 49 | $337,951 | Nov 12 | Lucky Red | false |
| 31 | Precious | - | - | - | $224,065 | 77 | $767,729 | Nov 26 | Fandango | false |
| 32 | The Illusionist | - | - | - | $222,041 | 19 | $317,410 | Oct 29 | Sacher Distribuzione | false |
| 33 | Mammuth | - | - | - | $196,725 | 28 | $302,913 | Oct 29 | Fandango | false |
| 34 | The Killer Inside Me | - | - | - | $192,146 | 83 | $416,443 | Nov 26 | BIM Distribuzione | false |
| 35 | The Flowers of Kirkuk | - | - | - | $190,339 | 25 | $224,084 | Nov 19 | Medusa Distribuzione | false |
| 36 | Fair Game | - | - | - | $187,354 | 199 | $1,248,756 | Oct 22 | Eagle Pictures | false |
| 37 | The Extraordinary Adventures of Adèle Blanc-Sec | - | - | - | $145,944 | 260 | $2,191,940 | Oct 15 | Medusa Distribuzione | false |
| 38 | Petty Letters and Love Crimes | - | - | - | $127,563 | 70 | $127,563 | Nov 19 | 01 Distribution | false |
| 39 | Animal Kingdom | - | - | - | $118,882 | 36 | $190,504 | Oct 29 | Mikado Film | false |
| 40 | Dinner for Schmucks | - | - | - | $110,842 | 51 | $110,842 | Nov 5 | United International Pictures | false |
| 41 | Buried | - | - | - | $94,349 | 166 | $2,127,617 | Oct 15 | - | false |
| 42 | The City of Your Final Destination | - | - | - | $93,909 | 58 | $916,654 | Oct 8 | Teodora Film | false |
| 43 | My Name Is Khan | - | - | - | $67,539 | 52 | $152,972 | Nov 26 | 20th Century Fox International | false |
| 44 | Gorbaciof | - | - | - | $66,996 | 133 | $879,825 | Oct 15 | Lucky Red | false |
| 45 | Seraphine | - | - | - | $52,374 | 12 | $169,425 | Oct 22 | One Movie | false |
| 46 | The Solitude of Prime Numbers | - | - | - | $49,782 | 371 | $4,928,162 | Sep 10 | Medusa Distribuzione | false |
| 47 | A Second Childhood | - | - | - | $48,305 | 189 | $1,367,507 | Oct 8 | 01 Distribution | false |
| 48 | Let It Be | - | - | - | $42,126 | 21 | $72,776 | Nov 19 | Bolero Film | false |
| 49 | The Black Sheep | - | - | - | $41,149 | 66 | $820,140 | Oct 1 | BIM Distribuzione | false |
| 50 | Edge of Darkness | - | - | - | $19,514 | 272 | $1,820,221 | Mar 19 | 01 Distribution | false |
| 51 | Illégal | - | - | - | $16,209 | 11 | $25,452 | Nov 19 | - | false |
| 52 | Eat Pray Love | - | - | - | $13,612 | 320 | $5,000,639 | Sep 17 | Sony Pictures Releasing | false |
| 53 | Passione | - | - | - | $10,987 | 39 | $452,105 | Oct 22 | 01 Distribution | false |
| 54 | Saw VI | - | - | - | $10,201 | 300 | $2,520,502 | Jun 1 | 01 Distribution | false |
| 55 | Saw II | - | - | - | $5,170 | 275 | $6,984,945 | Jan 6 | 01 Distribution | false |
| 56 | Nowhere Boy | - | - | - | $2,937 | 13 | $84,992 | Dec 3 | 01 Distribution | false |
| 57 | Post Mortem | - | - | - | $2,423 | 2 | $48,190 | Oct 29 | Archibald | false |
| 58 | Mia and the Migoo 2010 Re-release | - | - | - | $2,187 | 4 | $35,873 | Nov 26 | - | false |
| 59 | Remembering the Children | - | - | - | $1,584 | 22 | $263,808 | Jun 11 | Teodora Film | false |
| 60 | School Is Over | - | - | - | $1,496 | 1 | $49,802 | Nov 12 | Bolero Film | false |
