| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Twilight Saga: New Moon | - | - | - | $4,338,579 | 91 | $6,142,938 | Nov 19 | Belga Films | false |
| 2 | 2012 | - | - | - | $4,311,988 | 98 | $6,322,004 | Nov 11 | Sony Pictures Releasing | false |
| 3 | Up | - | - | - | $2,744,410 | 132 | $7,088,865 | Oct 7 | Walt Disney Pictures | false |
| 4 | This Is It | - | - | - | $1,741,259 | 62 | $2,795,161 | Oct 28 | Sony Pictures Releasing | false |
| 5 | Das Lied der Dinge | - | - | - | $1,416,262 | 33 | $3,589,842 | Oct 7 | Kinepolis Film Distribution (KFD) | false |
| 6 | The Box | - | - | - | $783,077 | 29 | $947,541 | Nov 4 | Benelux Film Distributors | false |
| 7 | The Barons | - | - | - | $663,928 | 13 | $1,266,035 | Nov 4 | Cinéart | false |
| 8 | A Christmas Carol | - | - | - | $657,646 | 66 | $1,769,393 | Nov 18 | Walt Disney Pictures | false |
| 9 | Little Nicholas | - | - | - | $653,090 | 30 | $1,905,136 | Sep 30 | Cinéart | false |
| 10 | Fame | - | - | - | $556,128 | 47 | $1,992,120 | Oct 7 | Kinepolis Film Distribution (KFD) | false |
| 11 | Surrogates | - | - | - | $520,216 | 53 | $1,237,516 | Oct 21 | Walt Disney Pictures | false |
| 12 | Cirque du Freak: The Vampire's Assistant | - | - | - | $461,517 | 30 | $513,855 | Nov 4 | Universal Pictures International (UPI) | false |
| 13 | Astro Boy | - | - | - | $384,471 | 44 | $507,079 | Oct 28 | Belga Films | false |
| 14 | The Concert | - | - | - | $310,951 | 15 | $820,323 | Nov 11 | Cinéart | false |
| 15 | Dance Flick | - | - | - | $284,386 | 21 | $437,491 | Oct 28 | Universal Pictures International (UPI) | false |
| 16 | Trésor | - | - | - | $281,919 | 14 | $324,589 | Nov 11 | Alternative Films | false |
| 17 | Micmacs | - | - | - | $245,235 | 45 | $400,517 | Oct 28 | Cinéart | false |
| 18 | The Rebound | - | - | - | $243,037 | 27 | $356,704 | Nov 11 | Paradiso Entertainment | false |
| 19 | Lucky Luke | - | - | - | $221,472 | 24 | $465,170 | Oct 21 | Les Films de l'Elysée | false |
| 20 | The White Ribbon | - | - | - | $219,391 | 17 | $497,190 | Oct 21 | Cinéart | false |
| 21 | Sinterklaas en de verdwenen pakjesboot | - | - | - | $213,908 | 16 | $279,115 | Oct 28 | Kinepolis Film Distribution (KFD) | false |
| 22 | Inglourious Basterds | - | - | - | $210,758 | 71 | $5,339,232 | Aug 19 | Universal Pictures International (UPI) | false |
| 23 | 500 Days of Summer | - | - | - | $183,079 | 11 | $243,919 | Nov 4 | 20th Century Fox International | false |
| 24 | Jennifer's Body | - | - | - | $181,041 | 35 | $578,583 | Oct 21 | 20th Century Fox International | false |
| 25 | G-Force | - | - | - | $173,737 | 79 | $3,144,067 | Jul 29 | Walt Disney Pictures | false |
| 26 | Paranormal Activity | - | - | - | $158,684 | 20 | $1,155,278 | Nov 25 | Kinepolis Film Distribution (KFD) | false |
| 27 | Love Happens | - | - | - | $139,156 | 16 | $198,539 | Nov 18 | A-Film Distribution | false |
| 28 | The Ugly Truth | - | - | - | $126,892 | 35 | $1,541,791 | Sep 23 | Sony Pictures Releasing | false |
| 29 | Lilly the Witch: The Dragon and the Magic Book | - | - | - | $104,377 | 10 | $201,899 | Feb 18 | Kinepolis Film Distribution (KFD) | false |
| 30 | The Informant! | - | - | - | $97,264 | 7 | $227,494 | Nov 18 | Warner Bros. | false |
| 31 | Twilight | - | - | - | $93,631 | 54 | $3,294,541 | Nov 26 | Belga Films | false |
| 32 | My Sister's Keeper | - | - | - | $80,859 | 20 | $202,332 | Nov 25 | Warner Bros. | false |
| 33 | My Queen Karo | - | - | - | $73,015 | 10 | $102,161 | Oct 28 | Kinepolis Film Distribution (KFD) | false |
| 34 | Wild Grass | - | - | - | $50,417 | 8 | $61,419 | Nov 4 | - | false |
| 35 | Whatever Works | - | - | - | $47,139 | 21 | $395,542 | Sep 30 | Paradiso Entertainment | false |
| 36 | Departures | - | - | - | $44,611 | 6 | $65,851 | Nov 4 | - | false |
| 37 | Ice Age: Dawn of the Dinosaurs | - | - | - | $44,424 | 160 | $9,755,324 | Jul 1 | 20th Century Fox International | false |
| 38 | Whiteout | - | - | - | $35,511 | 12 | $54,362 | Nov 4 | Universal Pictures International (UPI) | false |
| 39 | District 9 | - | - | - | $31,129 | 32 | $871,010 | Sep 30 | Sony Pictures Releasing | false |
| 40 | The Taking of Pelham 123 | - | - | - | $28,466 | 45 | $1,579,177 | Jul 29 | Sony Pictures Releasing | false |
| 41 | Fish Tank | - | - | - | $26,484 | 8 | $95,025 | Nov 25 | Cinéart | false |
| 42 | Julie & Julia | - | - | - | $17,817 | 18 | $265,006 | Oct 14 | Sony Pictures Releasing | false |
| 43 | Altiplano | - | - | - | $15,910 | 6 | $154,835 | Nov 25 | - | false |
| 44 | The Final Destination | - | - | - | $15,005 | 41 | $1,405,282 | Sep 16 | Warner Bros. | false |
| 45 | A Perfect Getaway | - | - | - | $13,288 | 23 | $693,518 | Aug 26 | A-Film Distribution | false |
| 46 | The Storm | - | - | - | $12,175 | 9 | $134,457 | Sep 30 | Universal Pictures International (UPI) | false |
| 47 | Het geheim van Mega Mindy | - | - | - | $9,254 | 33 | $1,731,315 | Jul 1 | Kinepolis Film Distribution (KFD) | false |
| 48 | Simon Konianski | - | - | - | $5,814 | 8 | $6,296 | Nov 25 | - | false |
