| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Harry Potter and the Goblet of Fire | - | - | - | $11,403,988 | 697 | $24,274,111 | Nov 25 | Warner Bros. | false |
| 2 | Flightplan | - | - | - | $5,909,800 | 303 | $6,135,492 | Nov 4 | Buena Vista International | false |
| 3 | Melissa P. | - | - | - | $5,314,338 | 297 | $7,175,149 | Nov 18 | Sony Pictures Releasing | false |
| 4 | Corpse Bride | - | - | - | $4,630,761 | 282 | $5,893,918 | Oct 28 | Warner Bros. | false |
| 5 | The Interpreter | - | - | - | $4,379,369 | 360 | $6,726,536 | Oct 28 | United International Pictures | false |
| 6 | The Tiger and the Snow | - | - | - | $4,176,293 | 754 | $17,451,649 | Oct 14 | 01 Distribution | false |
| 7 | La seconda notte di nozze | - | - | - | $3,233,366 | 241 | $4,235,042 | Nov 11 | 01 Distribution | false |
| 8 | March of the Penguins | - | - | - | $2,898,929 | 313 | $4,036,047 | Nov 18 | Lucky Red | false |
| 9 | The Legend of Zorro | - | - | - | $2,876,839 | 440 | $4,129,361 | Oct 28 | Sony Pictures Releasing | false |
| 10 | The Brothers Grimm | - | - | - | $2,831,514 | 246 | $2,860,077 | Nov 11 | Buena Vista International | false |
| 11 | Elizabethtown | - | - | - | $2,515,207 | 198 | $2,653,862 | Nov 4 | United International Pictures | false |
| 12 | Oliver Twist | - | - | - | $2,369,254 | 301 | $5,014,686 | Oct 21 | Medusa Distribuzione | false |
| 13 | Crash | - | - | - | $1,481,865 | 140 | $3,535,519 | Nov 11 | Filmauro | false |
| 14 | Lord of War | - | - | - | $1,156,350 | 143 | $1,461,115 | Nov 18 | Italian International Film | false |
| 15 | In Her Shoes | - | - | - | $1,143,841 | 186 | $1,313,493 | Nov 11 | 20th Century Fox International | false |
| 16 | Cry Wolf | - | - | - | $1,022,302 | 184 | $18,838,390 | Nov 25 | Eagle Pictures | false |
| 17 | Valiant | - | - | - | $927,757 | 170 | $1,139,363 | Oct 28 | Medusa Distribuzione | false |
| 18 | An Unfinished Life | - | - | - | $785,724 | 163 | $883,431 | Nov 18 | Eagle Pictures | false |
| 19 | Monster-in-Law | - | - | - | $607,110 | 310 | $5,173,546 | Oct 7 | Eagle Pictures | false |
| 20 | Romanzo Criminale | - | - | - | $507,552 | 306 | $5,482,452 | Sep 30 | Warner Bros. | false |
| 21 | Edison | - | - | - | $502,753 | 144 | $502,753 | Nov 11 | Warner Bros. | false |
| 22 | Charlie and the Chocolate Factory | - | - | - | $410,997 | 389 | $12,487,531 | Sep 23 | Warner Bros. | false |
| 23 | Sophie Scholl: The Final Days | - | - | - | $386,727 | 54 | $1,034,241 | Oct 28 | Istituto Luce | false |
| 24 | Caché | - | - | - | $383,468 | 78 | $1,336,153 | Oct 14 | BIM Distribuzione | false |
| 25 | Red Eye | - | - | - | $365,728 | 197 | $1,602,083 | Oct 21 | United International Pictures | false |
| 26 | The Exorcism of Emily Rose | - | - | - | $309,214 | 311 | $5,751,578 | Oct 7 | Sony Pictures Releasing | false |
| 27 | Everything Is Illuminated | - | - | - | $231,499 | 25 | $1,094,152 | Nov 11 | Warner Bros. | false |
| 28 | Go for Zucker | - | - | - | $119,595 | 41 | $505,556 | Nov 25 | Lady Film | false |
| 29 | Transporter 2 | - | - | - | $112,558 | 75 | $194,529 | Nov 25 | 20th Century Fox International | false |
| 30 | Goal! The Dream Begins | - | - | - | $93,995 | 53 | $93,995 | Nov 18 | Buena Vista International | false |
| 31 | Live and Become | - | - | - | $90,776 | 54 | $316,099 | Nov 4 | Medusa Distribuzione | false |
| 32 | Viva Zapatero! | - | - | - | $89,965 | 78 | $1,890,632 | Sep 16 | Lucky Red | false |
| 33 | The Big White | - | - | - | $89,789 | 80 | $95,009 | Nov 18 | Medusa Distribuzione | false |
| 34 | Wolf Creek | - | - | - | $87,332 | 53 | $89,023 | Nov 18 | Time Code | false |
| 35 | The Beat That My Heart Skipped | - | - | - | $76,411 | 34 | $105,024 | Nov 11 | BIM Distribuzione | false |
| 36 | Serenity | - | - | - | $67,908 | 97 | $107,531 | Nov 25 | United International Pictures | false |
| 37 | Never Again as Before | - | - | - | $67,218 | 72 | $296,888 | Nov 11 | Medusa Distribuzione | false |
| 38 | The Bow | - | - | - | $34,026 | 19 | $74,419 | Oct 28 | Mikado Film | false |
| 39 | Madagascar | - | - | - | $33,233 | 470 | $28,044,781 | Sep 2 | United International Pictures | false |
| 40 | Good Night, and Good Luck. | - | - | - | $7,691 | 195 | $2,890,928 | Sep 16 | Mediafilm | false |
