| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Fatal Attraction | - | - | - | $36,242,662 | 1,401 | $156,645,693 | Sep 18 | Paramount Pictures | false |
| 2 | The Running Man | - | - | - | $25,350,952 | 1,694 | $38,122,105 | Nov 13 | TriStar Pictures | false |
| 3 | Hello Again | - | - | - | $16,721,673 | 1,207 | $20,419,446 | Nov 6 | Walt Disney Studios Motion Pictures | false |
| 4 | Baby Boom | - | - | - | $13,452,729 | 892 | $26,712,476 | Oct 9 | United Artists | false |
| 5 | Cinderella 1987 Re-release | - | - | - | $12,184,410 | 1,657 | $34,101,149 | Nov 20 | Walt Disney Studios Motion Pictures | false |
| 6 | Three Men and a Baby | - | - | - | $11,018,269 | 1,813 | $167,780,960 | Nov 25 | Walt Disney Studios Motion Pictures | false |
| 7 | Fatal Beauty | - | - | - | $10,963,071 | 1,117 | $12,046,526 | Oct 30 | Metro-Goldwyn-Mayer (MGM) | false |
| 8 | Nuts | - | - | - | $9,852,141 | 1,112 | $30,950,002 | Nov 20 | Warner Bros. | false |
| 9 | Suspect | - | - | - | $9,846,021 | 1,029 | $18,782,400 | Oct 23 | TriStar Pictures | false |
| 10 | Dirty Dancing | - | - | - | $9,512,292 | 1,012 | $63,446,382 | Aug 21 | Vestron Pictures | false |
| 11 | The Princess Bride | - | - | - | $9,192,599 | 803 | $30,857,814 | Sep 25 | Twentieth Century Fox | false |
| 12 | Flowers in the Attic | - | - | - | $8,964,916 | 1,095 | $15,151,736 | Nov 20 | New World Pictures | false |
| 13 | Less Than Zero | - | - | - | $8,944,107 | 871 | $12,396,383 | Nov 6 | Twentieth Century Fox | false |
| 14 | The Hidden | - | - | - | $8,749,864 | 1,045 | $9,747,988 | Oct 30 | New Line Cinema | false |
| 15 | Planes, Trains & Automobiles | - | - | - | $8,184,156 | 1,684 | $49,530,280 | Nov 25 | Paramount Pictures | false |
| 16 | Like Father Like Son | - | - | - | $7,719,019 | 1,277 | $34,377,585 | Oct 2 | TriStar Pictures | false |
| 17 | Prince of Darkness | - | - | - | $7,130,592 | 1,239 | $14,182,492 | Oct 23 | Universal Pictures | false |
| 18 | Hiding Out | - | - | - | $7,019,441 | 988 | $7,019,441 | Nov 6 | De Laurentiis Entertainment Group (DEG) | false |
| 19 | Death Wish 4: The Crackdown | - | - | - | $6,880,310 | 1,030 | $6,880,310 | Nov 6 | Cannon Film Distributors | false |
| 20 | Teen Wolf Too | - | - | - | $4,988,918 | 1,540 | $7,888,703 | Nov 20 | Atlantic Releasing Corporation | false |
| 21 | Made in Heaven | - | - | - | $4,572,845 | 898 | $4,572,845 | Nov 6 | Lorimar Motion Pictures | false |
| 22 | Stakeout | - | - | - | $3,474,980 | 1,364 | $65,673,233 | Aug 7 | Walt Disney Studios Motion Pictures | false |
| 23 | Sign 'o' the Times | - | - | - | $3,000,073 | 234 | $3,000,073 | Nov 20 | - | false |
| 24 | The Sicilian | - | - | - | $2,837,636 | 370 | $5,406,879 | Oct 23 | Twentieth Century Fox | false |
| 25 | Russkies | - | - | - | $2,189,047 | 604 | $2,189,047 | Nov 6 | New Century | false |
| 26 | Date with an Angel | - | - | - | $1,988,962 | 843 | $1,988,962 | Nov 20 | De Laurentiis Entertainment Group (DEG) | false |
| 27 | Someone to Watch Over Me | - | - | - | $1,846,434 | 894 | $10,278,549 | Oct 9 | Columbia Pictures | false |
| 28 | Weeds | - | - | - | $1,560,269 | 86 | $2,325,444 | Oct 16 | De Laurentiis Entertainment Group (DEG) | false |
| 29 | From a Whisper to a Scream | - | - | - | $1,200,737 | 137 | $1,355,728 | Sep 4 | - | false |
| 30 | Cry Freedom | - | - | - | $1,180,156 | 479 | $5,899,797 | Nov 6 | Universal Pictures | false |
| 31 | Housekeeping | - | - | - | $1,051,111 | 2 | $1,083,282 | Nov 25 | Columbia Pictures | false |
| 32 | Cross My Heart | - | - | - | $1,025,762 | 205 | $1,025,762 | Nov 13 | Universal Pictures | false |
| 33 | Steel Dawn | - | - | - | $562,187 | 290 | $562,187 | Nov 6 | Vestron Pictures | false |
| 34 | The Last Emperor | - | - | - | $466,638 | 877 | $43,984,230 | Nov 20 | Columbia Pictures | false |
| 35 | Sammy and Rosie Get Laid | - | - | - | $39,505 | 15 | $1,196,336 | Oct 30 | Cinecom Pictures | false |
| 36 | Siesta | - | - | - | $32,041 | 30 | $700,000 | Nov 11 | Lorimar Motion Pictures | false |
