| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Kingdom of the Planet of the Apes | - | - | - | $2,632,316 | 452 | $3,167,601 | May 9 | Walt Disney Pictures | false |
| 2 | Challengers | - | - | - | $2,136,100 | 562 | $4,722,889 | Apr 25 | Warner Bros. | false |
| 3 | The Fall Guy | - | - | - | $1,662,706 | 363 | $2,365,865 | May 2 | Universal Pictures International (UPI) | false |
| 4 | Sarò con te | - | - | - | $1,537,306 | 155 | $1,537,306 | May 4 | Nexo Digital | false |
| 5 | IF | - | - | - | $1,514,845 | 461 | $2,246,442 | May 16 | Paramount Pictures International | false |
| 6 | The Garfield Movie | - | - | - | $1,374,714 | 472 | $2,259,589 | May 2 | Eagle Pictures | false |
| 7 | Il segreto di Liberato | - | - | - | $1,187,060 | 288 | $1,212,508 | May 9 | - | false |
| 8 | Tarot | - | - | - | $1,138,681 | 257 | $1,176,814 | May 9 | Eagle Pictures | false |
| 9 | Furiosa: A Mad Max Saga | - | - | - | $1,019,191 | 466 | $1,844,434 | May 23 | Warner Bros. | false |
| 10 | Trust | - | - | - | $646,131 | 447 | $1,942,017 | Apr 23 | - | false |
| 11 | The Taste of Things | - | - | - | $551,126 | 214 | $750,217 | May 9 | Lucky Red | false |
| 12 | Back to Black | - | - | - | $340,103 | 447 | $2,468,899 | Apr 18 | Universal Pictures International (UPI) | false |
| 13 | Wicked Little Letters | - | - | - | $331,908 | 254 | $1,647,908 | Apr 18 | BIM Distribuzione | false |
| 14 | Civil War | - | - | - | $329,081 | 668 | $1,985,972 | Apr 18 | 01 Distribution | false |
| 15 | Un mondo a parte | - | - | - | $329,034 | 652 | $8,108,856 | Mar 28 | Medusa Distribuzione | false |
| 16 | Anselm | - | - | - | $300,419 | 180 | $432,015 | May 2 | Lucky Red | false |
| 17 | The Monk and the Gun | - | - | - | $265,232 | 72 | $388,053 | May 2 | Officine UBU | false |
| 18 | Mothers' Instinct | - | - | - | $230,787 | 249 | $233,790 | May 9 | Vértice 360 | false |
| 19 | Sei fratelli | - | - | - | $229,618 | 245 | $309,243 | May 1 | 01 Distribution | false |
| 20 | Ghostbusters: Frozen Empire | - | - | - | $225,844 | 442 | $3,021,690 | Apr 11 | Columbia Pictures | false |
| 21 | Vangelo Secondo Maria | - | - | - | $224,495 | 324 | $292,979 | May 23 | - | false |
| 22 | Una storia nera | - | - | - | $148,282 | 252 | $148,282 | May 16 | 01 Distribution | false |
| 23 | Marcello Mio | - | - | - | $132,692 | 199 | $182,642 | May 23 | Lucky Red | false |
| 24 | La haine | - | - | - | $113,825 | 98 | $334,056 | May 13 | - | false |
| 25 | Ennio Doris - C'è anche domani | - | - | - | $99,865 | 20 | $775,395 | Apr 18 | Medusa Distribuzione | false |
| 26 | The Damned | - | - | - | $84,287 | 73 | $102,935 | May 16 | Lucky Red | false |
| 27 | Bonnard: Pierre & Marthe | - | - | - | $72,679 | 93 | $75,860 | May 16 | I Wonder Pictures | false |
| 28 | Gloria! | - | - | - | $62,998 | 265 | $575,154 | Apr 11 | 01 Distribution | false |
| 29 | Troppo azzurro | - | - | - | $55,462 | 63 | $56,696 | May 9 | - | false |
| 30 | My Place Is Here | - | - | - | $55,367 | 57 | $57,655 | May 9 | Adler Entertainment | false |
| 31 | Godzilla x Kong: The New Empire | - | - | - | $47,038 | 433 | $4,470,737 | Mar 28 | Warner Bros. | false |
| 32 | Palazzina Laf | - | - | - | $46,810 | 111 | $1,157,178 | Nov 30 | BIM Distribuzione | false |
| 33 | Past Lives | - | - | - | $45,853 | 474 | $3,592,280 | Feb 14 | Lucky Red | false |
| 34 | The President's Wife | - | - | - | $40,591 | 107 | $155,684 | Apr 24 | Europictures | false |
| 35 | Kung Fu Panda 4 | - | - | - | $38,959 | 591 | $12,803,184 | Mar 21 | Universal Pictures International (UPI) | false |
| 36 | The First Omen | - | - | - | $38,043 | 301 | $1,164,583 | Apr 4 | Walt Disney Pictures | false |
| 37 | Zamora | - | - | - | $34,341 | 295 | $816,336 | Apr 4 | 01 Distribution | false |
| 38 | The Goldman Case | - | - | - | $33,032 | 37 | $54,141 | May 23 | Movies Inspired | false |
| 39 | The Teachers' Lounge | - | - | - | $30,245 | 237 | $1,529,986 | Feb 29 | Lucky Red | false |
| 40 | Spy x Family Code: White | - | - | - | $25,238 | 215 | $323,481 | Apr 23 | Columbia Pictures | false |
| 41 | Io e il Secco | - | - | - | $19,483 | 48 | $19,483 | May 23 | Europictures | false |
| 42 | Tatami | - | - | - | $19,405 | 156 | $329,507 | Apr 4 | BIM Distribuzione | false |
| 43 | Sound of Freedom | - | - | - | $18,550 | 88 | $707,500 | Feb 19 | Dominus Production | false |
| 44 | And the Party Goes On | - | - | - | $18,483 | 118 | $325,180 | Apr 11 | Lucky Red | false |
| 45 | Explanation for Everything | - | - | - | $15,868 | 14 | $40,641 | May 1 | Arthouse | false |
| 46 | Io Capitano | - | - | - | $12,121 | 321 | $5,483,512 | Sep 7 | 01 Distribution | false |
| 47 | La casa di Ninetta | - | - | - | $9,279 | 9 | $9,279 | - | - | false |
| 48 | Just the Two of Us | - | - | - | $8,955 | 9 | $24,726 | May 2 | Movies Inspired | false |
| 49 | All of Us Strangers | - | - | - | $7,715 | 281 | $796,548 | Feb 29 | Walt Disney Pictures | false |
| 50 | Benson - La vita è il nemico | - | - | - | $7,304 | 17 | $26,790 | Feb 16 | - | false |
| 51 | Volare | - | - | - | $7,241 | 214 | $693,953 | Feb 22 | Fandango | false |
| 52 | Junkyard Dog | - | - | - | $6,619 | 20 | $9,757 | May 23 | Nomad Entertainment | false |
| 53 | L'amore e la gloria - La giovane Deledda | - | - | - | $6,145 | 9 | $7,528 | - | - | false |
| 54 | Girasoli | - | - | - | $5,906 | 15 | $5,906 | May 23 | - | false |
| 55 | There's Still Tomorrow | - | - | - | $4,566 | 694 | $40,632,735 | Oct 26 | - | false |
| 56 | Fantastic Machine | - | - | - | $4,170 | 20 | $4,170 | May 9 | Teodora Film | false |
| 57 | Poor Things | - | - | - | $3,866 | 552 | $10,038,975 | Jan 25 | Walt Disney Pictures | false |
| 58 | Food for Profit | - | - | - | $3,372 | 77 | $516,027 | Feb 29 | Mescalito Film | false |
| 59 | All to Play For | - | - | - | $2,990 | 16 | $19,175 | May 16 | Wanted | false |
| 60 | Samsara | - | - | - | $2,689 | 4 | $13,195 | May 10 | - | false |
| 61 | The Last Bus | - | - | - | $2,626 | 28 | $126,238 | Jan 25 | Celsius Entertainment | false |
| 62 | Neve | - | - | - | $2,445 | 32 | $247,363 | Feb 20 | - | false |
| 63 | Unbelievers | - | - | - | $2,367 | 5 | $48,698 | Sep 28 | - | false |
| 64 | One Life | - | - | - | $2,197 | 301 | $2,847,396 | Dec 21 | Eagle Pictures | false |
| 65 | Dune: Part Two | - | - | - | $2,161 | 553 | $10,823,082 | Feb 28 | Warner Bros. | false |
| 66 | Romeo è Giulietta | - | - | - | $2,088 | 469 | $1,648,515 | Feb 15 | - | false |
| 67 | Wish | - | - | - | $287 | 553 | $10,679,550 | Dec 21 | Walt Disney Pictures | false |
