Italian Box Office For May 2022
| Rank | Release | Gross | Max Th | Opening | % of Total | Open Th | Open | Close | Distributor |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Doctor Strange in the Multiverse of Madness | $14,487,541 | 577 | $6,579,103 | 45.4% | 543 | May 4 | - | Walt Disney Pictures |
| 2 | Top Gun: Maverick | $13,995,686 | 548 | $2,879,141 | 20.6% | 548 | May 27 | - | Paramount Pictures International |
| 3 | Nostalgia | $1,525,762 | 442 | $457,188 | 30% | 442 | May 25 | - | Medusa Distribuzione |
| 4 | Exterior Night | $539,166 | 313 | $184,257 | 34.2% | 305 | May 19 | - | Lucky Red |
| 5 | Operation Mincemeat | $456,820 | 384 | $174,982 | 38.3% | 353 | May 12 | - | Warner Bros. |
| 6 | Dog | $402,104 | 344 | $145,910 | 36.3% | 344 | May 12 | - | Notorious Pictures |
| 7 | Settembre | $296,020 | 272 | $145,884 | 49.3% | 272 | May 5 | - | 01 Distribution |
| 8 | The 355 | $226,773 | 260 | $80,255 | 35.4% | 260 | May 12 | - | 01 Distribution |
| 9 | The United States vs. Billie Holiday | $218,261 | 126 | $114,132 | 52.3% | 112 | May 5 | - | BIM Distribuzione |
| 10 | Firestarter | $132,996 | 251 | $70,590 | 53.1% | 251 | May 12 | - | Universal Pictures |
| 11 | Alcarràs | $116,862 | 90 | $44,341 | 37.9% | 90 | May 26 | - | I Wonder Pictures |
| 12 | American Night | $39,112 | 254 | $24,974 | 63.9% | 254 | May 19 | - | 01 Distribution |
| 13 | Gagarine | $34,009 | 52 | $17,067 | 50.2% | 52 | May 19 | - | Officine UBU |
| 14 | Zero Fucks Given | $23,951 | 42 | $13,156 | 54.9% | 42 | May 12 | - | I Wonder Pictures |
| 15 | La Grande Guerra del Salento | $22,825 | 15 | $21,694 | 95% | 15 | May 5 | - | - |
| 16 | Only the Animals | $21,796 | 27 | $11,851 | 54.4% | 24 | May 12 | - | Parthenos |
| 17 | On the Run | $20,733 | 54 | $16,512 | 79.6% | 54 | May 5 | - | - |
| 18 | Twenty One Pilots: Livestream Experience | $19,238 | 140 | $19,238 | 100% | 140 | May 19 | - | Nexo Digital |
| 19 | Koza Nostra | $7,846 | 77 | $7,846 | 100% | 77 | May 19 | - | Adler Entertainment |
| 20 | While at War | $5,064 | 20 | $5,064 | 100% | 20 | May 26 | - | Movies Inspired |
| 21 | Wild Nights with Emily | $4,495 | 13 | - | - | - | May 26 | - | - |
