| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: Dead Men Tell No Tales | - | - | - | $14,503,644 | 955 | $4,558,861 | 31.4% | 955 | May 24 | - | Walt Disney Pictures | false |
| 2 | Alien: Covenant | - | - | - | $2,834,020 | 480 | $1,239,104 | 43.7% | 480 | May 11 | - | 20th Century Fox International | false |
| 3 | Fortunata | - | - | - | $2,492,254 | 439 | $498,422 | 20% | 396 | May 20 | - | Universal Pictures International (UPI) | false |
| 4 | King Arthur: Legend of the Sword | - | - | - | $2,200,000 | 518 | $776,033 | 35.3% | 518 | May 10 | - | Warner Bros. | false |
| 5 | Get Out | - | - | - | $1,257,308 | 337 | $565,525 | 45% | 337 | May 18 | - | Universal Pictures International (UPI) | false |
| 6 | Friends by Chance | - | - | - | $1,191,233 | 221 | $272,230 | 22.9% | 192 | May 11 | - | 01 Distribution | false |
| 7 | Gold | - | - | - | $1,030,941 | 283 | $539,575 | 52.3% | 283 | May 4 | - | Eagle Pictures | false |
| 8 | Unlocked | - | - | - | $735,160 | 256 | $420,828 | 57.2% | 256 | May 4 | - | Notorious Pictures | false |
| 9 | 47 Meters Down | - | - | - | $676,904 | 241 | $238,011 | 35.2% | 241 | May 25 | - | Adler Entertainment | false |
| 10 | The Dinner | - | - | - | $636,883 | 226 | $250,405 | 39.3% | 216 | May 18 | - | Videa | false |
| 11 | Going in Style | - | - | - | $589,000 | 151 | $312,034 | 53% | 151 | May 4 | - | Warner Bros. | false |
| 12 | The Last Word | - | - | - | $337,903 | 91 | $147,000 | 43.5% | 91 | May 4 | - | Teodora Film | false |
| 13 | Little Bird's Big Adventure | - | - | - | $330,268 | 291 | $127,736 | 38.7% | 291 | May 11 | - | M2 Pictures | false |
| 14 | Song to Song | - | - | - | $288,310 | 261 | $159,079 | 55.2% | 261 | May 11 | - | Lucky Red | false |
| 15 | I peggiori | - | - | - | $248,126 | 253 | $165,714 | 66.8% | 253 | May 18 | - | Warner Bros. | false |
| 16 | After the Storm | - | - | - | $171,571 | 41 | $49,944 | 29.1% | 41 | May 25 | - | Tucker Film | false |
| 17 | Pure Hearts | - | - | - | $156,302 | 55 | $57,873 | 37% | 50 | May 25 | - | - | false |
| 18 | Sole cuore amore | - | - | - | $142,270 | 51 | $83,533 | 58.7% | 51 | May 4 | - | Koch Media | false |
| 19 | Snatched | - | - | - | $137,122 | 127 | - | - | - | May 25 | - | 20th Century Fox International | false |
| 20 | If I Were a Boy | - | - | - | $117,383 | 179 | $117,275 | 99.9% | 179 | May 11 | - | Adler Entertainment | false |
| 21 | Sicilian Ghost Story | - | - | - | $81,841 | 57 | $46,046 | 56.3% | 57 | May 18 | - | BIM Distribuzione | false |
| 22 | A Monster Calls | - | - | - | $61,206 | 114 | $61,206 | 100% | 114 | May 18 | - | 01 Distribution | false |
| 23 | Maradonapoli | - | - | - | $57,389 | 85 | $21,995 | 38.3% | 85 | May 4 | - | Warner Bros. | false |
| 24 | Orecchie | - | - | - | $54,681 | 22 | - | - | - | May 18 | - | 102 Distribution | false |
| 25 | On the Milky Road | - | - | - | $36,246 | 38 | $36,246 | 100% | 38 | May 11 | - | Europictures | false |
| 26 | The Night My Mother Killed My Father | - | - | - | $36,055 | 53 | $34,004 | 94.3% | 53 | May 18 | - | - | false |
| 27 | Monster Trucks | - | - | - | $35,031 | 76 | $35,031 | 100% | 76 | May 4 | - | Universal Pictures International (UPI) | false |