| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Avengers | - | - | - | $405,350 | 15 | $517,473 | Apr 27 | Walt Disney Pictures | false |
| 2 | Men in Black³ | - | - | - | $150,279 | 18 | $429,922 | May 25 | Sony Pictures Releasing | false |
| 3 | Safe House | - | - | - | $51,478 | 6 | $102,068 | Apr 20 | Universal Pictures International (UPI) | false |
| 4 | The Lucky One | - | - | - | $51,349 | 6 | $77,264 | May 18 | Warner Bros. | false |
| 5 | Battleship | - | - | - | $48,355 | 8 | $49,055 | May 11 | Universal Pictures International (UPI) | false |
| 6 | The Vow | - | - | - | $44,476 | 6 | $125,674 | Apr 13 | Sony Pictures Releasing | false |
| 7 | Beauty and the Beast 2012 3D Release | - | - | - | $41,398 | 8 | $45,486 | May 11 | Walt Disney Pictures | false |
| 8 | The Woman in Black | - | - | - | $34,881 | 3 | $102,320 | Apr 6 | - | false |
| 9 | One for the Money | - | - | - | $34,776 | 3 | $35,905 | May 11 | - | false |
| 10 | Margin Call | - | - | - | $33,409 | 3 | $41,164 | May 11 | - | false |
| 11 | La Culpa del Cordero | - | - | - | $32,681 | 6 | $42,924 | May 11 | - | false |
| 12 | Titanic 2012 3D Release | - | - | - | $29,915 | 9 | $225,706 | Apr 13 | 20th Century Fox International | false |
| 13 | Extraños en la noche | - | - | - | $26,410 | 5 | $26,410 | May 4 | Walt Disney Pictures | false |
| 14 | Carnage | - | - | - | $25,414 | 4 | $37,370 | Apr 27 | - | false |
| 15 | Drive | - | - | - | $17,883 | 3 | $21,203 | May 18 | - | false |
| 16 | Mirror Mirror | - | - | - | $16,904 | 7 | $96,640 | Apr 6 | - | false |
| 17 | The Salt of Life | - | - | - | $14,893 | 1 | $16,459 | May 4 | - | false |
| 18 | The Hunger Games | - | - | - | $14,795 | 9 | $185,791 | Mar 23 | - | false |
| 19 | The Lorax | - | - | - | $14,731 | 13 | $174,375 | Mar 30 | Universal Pictures International (UPI) | false |
| 20 | Shame | - | - | - | $14,705 | 2 | $17,201 | May 4 | - | false |
| 21 | Cave of Forgotten Dreams | - | - | - | $13,404 | 1 | $21,681 | Apr 13 | - | false |
| 22 | The First Beautiful Thing 2011 Re-release | - | - | - | $13,188 | 2 | $38,929 | Apr 13 | - | false |
| 23 | Last Night | - | - | - | $11,908 | 2 | $26,635 | Dec 16 | - | false |
| 24 | The Tree of Life | - | - | - | $10,277 | 1 | $27,866 | Apr 13 | - | false |
| 25 | The Debt | - | - | - | $6,499 | 3 | $49,522 | Mar 23 | Universal Pictures International (UPI) | false |
| 26 | My Afternoons with Margueritte | - | - | - | $4,345 | 1 | $83,726 | Nov 18 | - | false |
| 27 | Sidewalls | - | - | - | $4,123 | 2 | $9,261 | May 25 | - | false |
| 28 | 3 Millones | - | - | - | $3,091 | 10 | $146,248 | Nov 4 | - | false |
| 29 | We Need to Talk About Kevin | - | - | - | $2,852 | 1 | $3,299 | May 18 | - | false |
| 30 | Project X | - | - | - | $2,406 | 6 | $70,238 | Mar 16 | Warner Bros. | false |
| 31 | El cultivo de la flor invisible | - | - | - | $2,063 | 2 | $4,250 | May 25 | - | false |
| 32 | We Bought a Zoo | - | - | - | $1,926 | 8 | $67,229 | Feb 24 | 20th Century Fox International | false |
| 33 | Man on a Ledge | - | - | - | $1,023 | 5 | $63,110 | Mar 16 | - | false |
