| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Avengers | - | - | - | $11,004,775 | 679 | $22,012,517 | Apr 25 | Walt Disney Pictures | false |
| 2 | American Reunion | - | - | - | $7,554,916 | 410 | $7,878,279 | May 3 | United International Pictures | false |
| 3 | Dark Shadows | - | - | - | $7,107,330 | 541 | $8,830,490 | May 11 | Warner Bros. | false |
| 4 | Men in Black³ | - | - | - | $3,458,750 | 670 | $7,671,850 | May 23 | Warner Bros. | false |
| 5 | The Hunger Games | - | - | - | $2,660,288 | 535 | $3,834,276 | May 1 | Warner Bros. | false |
| 6 | To Rome with Love | - | - | - | $2,030,306 | 603 | $9,565,012 | Apr 20 | Medusa Distribuzione | false |
| 7 | The Cabin in the Woods | - | - | - | $1,272,768 | 265 | $1,527,772 | May 18 | M2 Pictures | false |
| 8 | The Lucky One | - | - | - | $949,748 | 281 | $1,948,392 | Apr 25 | Warner Bros. | false |
| 9 | Chronicle | - | - | - | $918,154 | 319 | $1,060,028 | May 9 | 20th Century Fox International | false |
| 10 | The Cold Light of Day | - | - | - | $749,202 | 228 | $777,495 | May 18 | - | false |
| 11 | The Rum Diary | - | - | - | $622,952 | 264 | $1,439,166 | Apr 24 | 01 Distribution | false |
| 12 | Cosmopolis | - | - | - | $612,226 | 273 | $1,001,528 | May 25 | 01 Distribution | false |
| 13 | Salmon Fishing in the Yemen | - | - | - | $568,821 | 197 | $680,122 | May 18 | M2 Pictures | false |
| 14 | Sea Level | - | - | - | $562,802 | 188 | $575,888 | May 3 | Moviemax | false |
| 15 | The Players | - | - | - | $544,464 | 158 | $544,424 | May 3 | BIM Distribuzione | false |
| 16 | The First Man | - | - | - | $463,407 | 76 | $954,811 | Apr 20 | 01 Distribution | false |
| 17 | Margin Call | - | - | - | $432,639 | 106 | $540,072 | May 18 | 01 Distribution | false |
| 18 | Castle in the Sky 2012 Re-release | - | - | - | $426,993 | 143 | $725,189 | Apr 25 | Lucky Red | false |
| 19 | Extremely Loud & Incredibly Close | - | - | - | $347,060 | 135 | $825,428 | May 23 | Warner Bros. | false |
| 20 | Cherry on the Cake | - | - | - | $320,133 | 50 | $1,094,191 | Apr 12 | Bolero Film | false |
| 21 | Hunger 2012 Re-release | - | - | - | $290,980 | 45 | $397,707 | Apr 27 | BIM Distribuzione | false |
| 22 | Special Forces | - | - | - | $277,094 | 148 | $277,094 | May 11 | Eagle Pictures | false |
| 23 | All Our Desires | - | - | - | $276,647 | 49 | $359,401 | May 11 | - | false |
| 24 | Sister | - | - | - | $274,297 | 38 | $442,434 | May 11 | Teodora Film | false |
| 25 | StreetDance 2 2012 Re-release | - | - | - | $264,771 | 251 | $1,718,734 | Apr 20 | Eagle Pictures | false |
| 26 | Operazione vacanze | - | - | - | $240,245 | 229 | $319,265 | May 23 | - | false |
| 27 | 100 metri dal paradiso | - | - | - | $209,640 | 171 | $209,640 | May 11 | 01 Distribution | false |
| 28 | Battleship | - | - | - | $196,144 | 420 | $5,747,869 | Apr 12 | United International Pictures | false |
| 29 | Diaz: Don't Clean Up This Blood | - | - | - | $183,708 | 243 | $2,558,925 | Apr 12 | Fandango | false |
| 30 | The Best Exotic Marigold Hotel | - | - | - | $165,409 | 132 | $1,110,398 | Mar 29 | 20th Century Fox International | false |
| 31 | Caesar Must Die | - | - | - | $84,949 | 41 | $961,469 | Mar 1 | Sacher Distribuzione | false |
| 32 | Mirror Mirror | - | - | - | $84,295 | 387 | $6,571,936 | Apr 4 | 01 Distribution | false |
| 33 | Little White Lies | - | - | - | $80,982 | 89 | $1,079,098 | Apr 6 | Lucky Red | false |
| 34 | Chicken with Plums | - | - | - | $64,865 | 41 | $541,904 | Apr 6 | Officine UBU | false |
| 35 | The Call | - | - | - | $54,753 | 19 | $141,327 | May 11 | - | false |
| 36 | Workers - Pronti a tutto | - | - | - | $53,120 | 78 | $53,120 | May 11 | - | false |
| 37 | Silent Souls 2012 Re-release | - | - | - | $46,623 | 28 | $95,864 | May 25 | - | false |
| 38 | This Means War | - | - | - | $43,018 | 167 | $560,455 | Apr 20 | 20th Century Fox International | false |
| 39 | It May Be Love But It Doesn't Show | - | - | - | $39,266 | 527 | $7,855,434 | Nov 24 | Medusa Distribuzione | false |
| 40 | Fallo per papà | - | - | - | $35,995 | 20 | $60,342 | May 25 | - | false |
| 41 | The Mill and the Cross | - | - | - | $29,991 | 11 | $206,470 | Mar 29 | - | false |
| 42 | Someday This Pain Will Be Useful to You | - | - | - | $26,214 | 201 | $666,922 | Feb 23 | 01 Distribution | false |
| 43 | My Worst Nightmare | - | - | - | $20,942 | 82 | $620,827 | Mar 29 | BIM Distribuzione | false |
| 44 | Chinese Take-Away | - | - | - | $20,822 | 29 | $367,010 | Mar 23 | - | false |
| 45 | The Lady | - | - | - | $15,600 | 75 | $458,943 | Mar 23 | - | false |
| 46 | A Magnificent Haunting | - | - | - | $8,458 | 444 | $3,950,054 | Mar 15 | 01 Distribution | false |
| 47 | Another Earth | - | - | - | $8,048 | 7 | $26,044 | May 25 | 20th Century Fox International | false |
| 48 | Maternity Blues | - | - | - | $7,764 | 10 | $43,397 | Apr 26 | Fandango | false |
| 49 | Roman Polanski: A Film Memoir | - | - | - | $6,582 | 6 | $31,222 | May 25 | Lucky Red | false |
| 50 | A Flat for Three | - | - | - | $5,408 | 609 | $11,398,541 | Mar 1 | Filmauro | false |
| 51 | Martha Marcy May Marlene | - | - | - | $5,224 | 11 | $13,454 | May 25 | 20th Century Fox International | false |
| 52 | The Artist | - | - | - | $4,093 | 127 | $3,528,704 | Dec 8 | BIM Distribuzione | false |
| 53 | Madang Amtark | - | - | - | $4,061 | 99 | $85,760 | Apr 20 | - | false |
| 54 | La casa nel vento dei morti | - | - | - | $3,192 | 4 | $38,447 | Apr 26 | DIA Distributori Indipendenti | false |
| 55 | Maledimiele | - | - | - | $3,071 | 4 | $18,048 | Apr 20 | - | false |
| 56 | Hugo | - | - | - | $3,013 | 467 | $9,526,733 | Feb 2 | 01 Distribution | false |
| 57 | Cave of Forgotten Dreams | - | - | - | $2,709 | 2 | $25,100 | Mar 8 | DIA Distributori Indipendenti | false |
| 58 | The Descendants | - | - | - | $2,665 | 313 | $4,054,051 | Feb 16 | 20th Century Fox International | false |
| 59 | Hysteria | - | - | - | $2,480 | 141 | $1,388,235 | Feb 23 | BIM Distribuzione | false |
| 60 | Days of Harvest | - | - | - | $1,929 | 3 | $91,024 | Feb 23 | Ierà | false |
| 61 | Shun Li and the Poet | - | - | - | $1,648 | 24 | $617,850 | Sep 22 | - | false |
| 62 | Wrath of the Titans | - | - | - | $1,452 | 350 | $5,447,003 | Mar 29 | Warner Bros. | false |
| 63 | Journey 2: The Mysterious Island | - | - | - | $1,208 | 437 | $5,908,558 | Feb 23 | Warner Bros. | false |
