| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: On Stranger Tides | - | - | - | $3,651,614 | 153 | $5,268,571 | May 18 | Walt Disney Pictures | false |
| 2 | Fast Five | - | - | - | $1,330,859 | 101 | $2,014,415 | Apr 28 | Universal Pictures International (UPI) | false |
| 3 | Thor | - | - | - | $986,546 | 105 | $1,477,787 | Apr 27 | Paramount Pictures International | false |
| 4 | Kung Fu Panda 2 | - | - | - | $858,467 | 133 | $2,286,825 | May 26 | - | false |
| 5 | Priest | - | - | - | $565,208 | 95 | $585,184 | May 12 | - | false |
| 6 | Hanna | - | - | - | $178,651 | 40 | $180,932 | May 5 | - | false |
| 7 | Hop | - | - | - | $166,476 | 81 | $468,158 | Apr 21 | Universal Pictures International (UPI) | false |
| 8 | Hall Pass | - | - | - | $166,325 | 45 | $366,149 | Apr 21 | Warner Bros. | false |
| 9 | Rio | - | - | - | $109,889 | 110 | $1,838,484 | Apr 7 | 20th Century Fox International | false |
| 10 | Utomlennye solntsem 2: Tsitadel | - | - | - | $99,128 | 32 | $99,128 | May 5 | - | false |
| 11 | Little Big Panda | - | - | - | $44,116 | 22 | $44,116 | May 5 | - | false |
| 12 | Scream 4 | - | - | - | $27,237 | 42 | $231,734 | Apr 14 | - | false |
| 13 | Generation P | - | - | - | $24,345 | 49 | $275,426 | Apr 14 | - | false |
| 14 | PiraMMMida | - | - | - | $8,888 | 32 | $120,769 | Apr 14 | - | false |
| 15 | Just Go with It | - | - | - | $7,814 | 59 | $918,252 | Mar 31 | Sony Pictures Releasing | false |
| 16 | Paul | - | - | - | $2,642 | 49 | $360,221 | Mar 24 | Universal Pictures International (UPI) | false |
| 17 | Sucker Punch | - | - | - | $1,783 | 50 | $213,496 | Mar 31 | Warner Bros. | false |
| 18 | Black Swan | - | - | - | $1,449 | 10 | $185,650 | Mar 10 | 20th Century Fox International | false |
| 19 | I Am Number Four | - | - | - | $1,245 | 77 | $555,952 | Feb 24 | Walt Disney Pictures | false |
| 20 | Red Riding Hood | - | - | - | $1,027 | 42 | $243,438 | Mar 24 | Warner Bros. | false |
| 21 | Rango | - | - | - | $548 | 86 | $1,005,795 | Mar 17 | Paramount Pictures International | false |
| 22 | Drive Angry | - | - | - | $38 | 59 | $566,160 | Mar 3 | Warner Bros. | false |
