| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Fast Five | - | - | - | $436,605 | 11 | $519,841 | May 5 | United International Pictures | false |
| 2 | Pirates of the Caribbean: On Stranger Tides | - | - | - | $264,017 | 11 | $475,742 | May 19 | Walt Disney Pictures | false |
| 3 | Thor | - | - | - | $175,404 | 10 | $282,342 | Apr 28 | United International Pictures | false |
| 4 | Rio | - | - | - | $130,278 | 11 | $440,337 | Apr 21 | 20th Century Fox International | false |
| 5 | The Hangover Part II | - | - | - | $93,927 | 9 | $452,330 | May 26 | Warner Bros. | false |
| 6 | Something Borrowed | - | - | - | $88,129 | 8 | $95,634 | May 5 | Jaguar Film International Distribution | false |
| 7 | Scream 4 | - | - | - | $85,694 | 7 | $92,910 | May 12 | Italian International Film | false |
| 8 | Priest | - | - | - | $63,574 | 9 | $68,507 | May 12 | Sony Pictures Releasing | false |
| 9 | Water for Elephants | - | - | - | $49,548 | 8 | $49,548 | May 5 | 20th Century Fox International | false |
| 10 | The Rite | - | - | - | $47,526 | 9 | $84,385 | Apr 28 | Warner Bros. | false |
| 11 | Limitless | - | - | - | $43,131 | 9 | $164,118 | Apr 21 | - | false |
| 12 | Blitz | - | - | - | $34,696 | 6 | $36,704 | May 12 | - | false |
| 13 | Arthur | - | - | - | $32,913 | 5 | $32,913 | May 12 | Warner Bros. | false |
| 14 | The Beaver | - | - | - | $30,660 | 9 | $35,527 | May 19 | Jaguar Film International Distribution | false |
| 15 | 365 Days of Happiness | - | - | - | $24,835 | 7 | $120,021 | Apr 7 | - | false |
| 16 | The Other Woman | - | - | - | $17,514 | 5 | $33,479 | Apr 28 | Italian International Film | false |
| 17 | Ironclad | - | - | - | $14,601 | 7 | $62,519 | Apr 21 | Italian International Film | false |
| 18 | Hanna | - | - | - | $13,240 | 8 | $37,424 | May 26 | Italian International Film | false |
| 19 | Space Dogs | - | - | - | $10,542 | 6 | $10,542 | May 19 | - | false |
| 20 | Hop | - | - | - | $7,013 | 8 | $88,037 | Apr 14 | United International Pictures | false |
| 21 | Incendies | - | - | - | $2,309 | 4 | $17,915 | Mar 17 | - | false |
| 22 | The Roommate | - | - | - | $2,063 | 6 | $44,425 | Apr 14 | Sony Pictures Releasing | false |
| 23 | Tamara Drewe | - | - | - | $2,003 | 6 | $3,860 | May 26 | - | false |
| 24 | Of Gods and Men | - | - | - | $1,491 | 5 | $35,547 | Mar 31 | Joseph Chacra & Sons | false |
| 25 | Source Code | - | - | - | $1,268 | 9 | $171,270 | Mar 31 | Jaguar Film International Distribution | false |
| 26 | Carlos | - | - | - | $490 | 5 | $14,915 | Apr 7 | - | false |
| 27 | The King's Speech | - | - | - | $395 | 5 | $132,260 | Feb 17 | Italian International Film | false |
| 28 | Fasel wa Na'ood | - | - | - | $303 | 4 | $16,860 | Apr 14 | - | false |
| 29 | The Eagle | - | - | - | $118 | 8 | $98,517 | Mar 17 | Italian International Film | false |
