Domestic Box Office For May 2010
| Rank | Release | Gross | Max Th | Opening | % of Total | Open Th | Open | Close | Distributor |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Iron Man 2 | $312,433,331 | 4,390 | $128,122,480 | 41% | 4,380 | May 7 | Aug 19 | Paramount Pictures |
| 2 | Shrek Forever After | $238,736,787 | 4,386 | $70,838,207 | 29.7% | 4,359 | May 21 | Sep 9 | DreamWorks |
| 3 | Robin Hood | $105,269,730 | 3,505 | $36,063,385 | 34.3% | 3,503 | May 14 | Aug 5 | Universal Pictures |
| 4 | Sex and the City 2 | $95,347,692 | 3,445 | $31,001,870 | 32.5% | 3,445 | May 27 | Aug 19 | Warner Bros. |
| 5 | Prince of Persia: The Sands of Time | $90,759,676 | 3,646 | $30,095,259 | 33.2% | 3,646 | May 28 | Sep 23 | Walt Disney Studios Motion Pictures |
| 6 | Letters to Juliet | $53,032,453 | 2,975 | $13,540,486 | 25.5% | 2,968 | May 14 | Aug 26 | Summit Entertainment |
| 7 | Just Wright | $21,540,363 | 1,831 | $8,284,989 | 38.5% | 1,831 | May 14 | Aug 5 | Fox Searchlight Pictures |
| 8 | MacGruber | $8,525,600 | 2,551 | $4,043,495 | 47.4% | 2,551 | May 21 | Jun 10 | Universal Pictures |
| 9 | Babies | $7,320,323 | 543 | $2,160,460 | 29.5% | 534 | May 7 | Jul 8 | Focus Features |
| 10 | Sea Rex 3D: Journey to a Prehistoric World | $6,096,582 | 14 | - | - | - | May 28 | Sep 13 | 3D Entertainment |
| 11 | Solitary Man | $4,360,548 | 177 | $94,936 | 2.2% | 4 | May 21 | Oct 7 | Anchor Bay Films |
| 12 | Kites | $1,643,486 | 207 | $959,329 | 58.4% | 207 | May 21 | Jun 24 | Reliance Big Pictures |
| 13 | Micmacs | $1,262,079 | 52 | $42,751 | 3.4% | 4 | May 28 | Oct 21 | Sony Pictures Classics |
| 14 | Mother and Child | $1,110,509 | 119 | $43,040 | 3.9% | 4 | May 7 | Oct 21 | Sony Pictures Classics |
| 15 | Princess Kaiulani | $883,887 | 47 | $186,995 | 21.2% | 33 | May 14 | Sep 30 | Roadside Attractions |
| 16 | Agora | $619,423 | 17 | $33,262 | 5.4% | 2 | May 28 | Oct 21 | Newmarket Films |
| 17 | Mademoiselle Chambon | $531,685 | 16 | $19,446 | 3.7% | 2 | May 28 | Jan 13 | Lorber Films |
| 18 | Metropolis 2010 Re-release | $529,603 | 9 | $19,978 | 3.8% | 2 | May 7 | Dec 23 | Kino International |
| 19 | Breathless 2010 Re-release | $363,031 | 12 | $32,424 | 8.9% | 4 | May 28 | Dec 16 | Rialto Pictures |
| 20 | Holy Rollers | $303,064 | 20 | $39,685 | 13.1% | 3 | May 21 | Aug 26 | First Independent Pictures |
| 21 | Casino Jack and the United States of Money | $176,865 | 21 | $28,234 | 16% | 9 | May 7 | Jul 8 | Magnolia Pictures |
| 22 | Only the Brave | $150,000 | 5 | $14,825 | 9.9% | 5 | May 28 | Jul 15 | Indican Pictures |
| 23 | Father of My Children | $144,022 | 7 | $10,414 | 7.2% | 1 | May 21 | Jul 1 | IFC Films |
| 24 | Survival of the Dead | $101,740 | 20 | $43,757 | 43% | 20 | May 28 | Jul 15 | Magnolia Pictures |
| 25 | OSS 117: Lost in Rio | $89,375 | 7 | $10,243 | 11.5% | 3 | May 7 | Aug 19 | Music Box Films |
| 26 | John Rabe | $67,519 | 6 | $4,892 | 7.2% | 3 | May 21 | Oct 14 | Strand Releasing |
| 27 | Racing Dreams | $65,082 | 33 | $20,048 | 30.8% | 33 | May 21 | Jul 22 | Hannover House |
| 28 | Looking for Eric | $55,804 | 11 | $6,743 | 12.1% | 2 | May 14 | Jul 1 | IFC Films |
| 29 | The Oath | $42,273 | 4 | $5,760 | 13.6% | 1 | May 7 | Jul 29 | Zeitgeist Films |
| 30 | Kites The Remix | $41,783 | 40 | $24,869 | 59.5% | 40 | May 28 | Jun 10 | Reliance Big Pictures |
| 31 | Beetle Queen Conquers Tokyo | $32,308 | 3 | $6,498 | 20.1% | 1 | May 12 | Jul 29 | Argot Pictures |
| 32 | 180° South | $31,745 | 4 | $10,269 | 32.3% | 4 | May 21 | Jun 10 | Magnolia Pictures |
| 33 | Multiple Sarcasms | $29,731 | 15 | $16,025 | 53.9% | 15 | May 7 | May 27 | MAC Releasing |
| 34 | Two in the Wave | $28,808 | 1 | $5,676 | 19.7% | 1 | May 19 | Oct 7 | Lorber Films |
| 35 | Here and There | $27,156 | 5 | $6,352 | 23.4% | 1 | May 14 | - | Cinema Purgatorio |
| 36 | Daddy Longlegs | $21,766 | 2 | $8,323 | 38.2% | 1 | May 14 | Jun 3 | IFC Films |
| 37 | Carbon Nation | $16,901 | 2 | $402 | 2.4% | 1 | May 7 | - | Clay Way Media |
| 38 | The Living Wake | $12,232 | 1 | $3,821 | 31.2% | 1 | May 14 | Jul 22 | Mangusta Productions |
| 39 | After the Cup: Sons of Sakhnin United | $11,538 | 3 | $2,501 | 21.7% | 1 | May 21 | Jun 24 | Variance Films |
| 40 | Happiness Runs | $7,199 | 2 | $2,674 | 37.1% | 1 | May 7 | May 27 | Strand Releasing |
| 41 | In/Significant Others | $3,763 | 1 | $1,408 | 37.4% | 1 | May 14 | Jul 29 | North Poplar Pictures |
| 42 | Perrier's Bounty | $828 | 1 | $828 | 100% | 1 | May 21 | May 27 | IFC Films |
