| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Robin Hood | - | - | - | $246,994 | 9 | $333,336 | May 13 | United International Pictures | false |
| 2 | Iron Man 2 | - | - | - | $154,432 | 8 | $165,313 | Apr 29 | United International Pictures | false |
| 3 | The Light of My Eyes | - | - | - | $153,485 | 10 | $473,018 | May 20 | - | false |
| 4 | Clash of the Titans | - | - | - | $122,459 | 9 | $353,010 | Apr 15 | Warner Bros. | false |
| 5 | The Back-up Plan | - | - | - | $86,332 | 7 | $110,529 | May 6 | Sony Pictures Releasing | false |
| 6 | She's Out of My League | - | - | - | $66,421 | 6 | $81,874 | May 6 | United International Pictures | false |
| 7 | Prince of Persia: The Sands of Time | - | - | - | $54,254 | 8 | $252,106 | May 27 | Walt Disney Pictures | false |
| 8 | Cop Out | - | - | - | $39,312 | 6 | $42,561 | May 6 | Warner Bros. | false |
| 9 | OceanWorld | - | - | - | $37,685 | 3 | $64,713 | Apr 22 | Prime Pictures | false |
| 10 | Toy Story 2 2009 Re-release | - | - | - | $34,613 | 6 | $37,002 | Apr 29 | Walt Disney Pictures | false |
| 11 | Date Night | - | - | - | $25,694 | 7 | $84,660 | Apr 8 | 20th Century Fox International | false |
| 12 | The Ghost Writer | - | - | - | $24,718 | 6 | $47,708 | Apr 22 | Jaguar Film International Distribution | false |
| 13 | The Last Song | - | - | - | $24,022 | 5 | $118,246 | Apr 1 | Walt Disney Pictures | false |
| 14 | The Bounty Hunter | - | - | - | $20,338 | 7 | $221,368 | Mar 25 | Sony Pictures Releasing | false |
| 15 | Hot Tub Time Machine | - | - | - | $16,434 | 6 | $16,434 | Apr 29 | Jaguar Film International Distribution | false |
| 16 | Nanny McPhee Returns | - | - | - | $14,435 | 6 | $29,697 | Apr 22 | United International Pictures | false |
| 17 | The Imaginarium of Doctor Parnassus | - | - | - | $13,477 | 3 | $13,477 | May 13 | - | false |
| 18 | Serious Moonlight | - | - | - | $11,143 | 4 | $13,633 | May 20 | - | false |
| 19 | Remember Me | - | - | - | $10,826 | 6 | $93,981 | Apr 1 | Jaguar Film International Distribution | false |
| 20 | How to Train Your Dragon | - | - | - | $10,614 | 7 | $139,341 | Mar 25 | United International Pictures | false |
| 21 | Captain Alatriste: The Spanish Musketeer 2010 Re-release | - | - | - | $8,158 | 5 | $16,903 | Apr 22 | Italian International Film | false |
| 22 | Kick-Ass | - | - | - | $6,400 | 4 | $15,321 | May 27 | - | false |
| 23 | 9 | - | - | - | $4,820 | 5 | $6,221 | May 20 | Italian International Film | false |
| 24 | My Name Is Khan | - | - | - | $4,164 | 7 | $61,406 | Mar 11 | 20th Century Fox International | false |
| 25 | Dorian Gray | - | - | - | $3,826 | 1 | $33,360 | Apr 1 | Prime Pictures | false |
| 26 | When in Rome | - | - | - | $3,663 | 7 | $121,320 | Feb 25 | Walt Disney Pictures | false |
| 27 | Precious | - | - | - | $3,443 | 3 | $5,964 | May 13 | Italian International Film | false |
| 28 | From My Window, Without a Home... | - | - | - | $3,441 | 4 | $4,630 | Apr 22 | Italian International Film | false |
| 29 | Blood and Bone | - | - | - | $3,103 | 4 | $3,492 | May 6 | Italian International Film | false |
| 30 | Alice in Wonderland | - | - | - | $2,567 | 8 | $430,952 | Mar 4 | Walt Disney Pictures | false |
| 31 | The Runaways | - | - | - | $2,428 | 5 | $3,724 | May 27 | Jaguar Film International Distribution | false |
| 32 | From Paris with Love | - | - | - | $1,739 | 7 | $179,264 | Feb 18 | Italian International Film | false |
| 33 | Shutter Island | - | - | - | $863 | 7 | $165,389 | Mar 11 | United International Pictures | false |
| 34 | Dear John | - | - | - | $745 | 3 | $42,078 | Mar 25 | - | false |
| 35 | Cold Souls | - | - | - | $679 | 1 | $872 | Apr 22 | - | false |
| 36 | Arthur and the Revenge of Maltazard | - | - | - | $669 | 6 | $18,066 | Apr 1 | Walt Disney Pictures | false |
| 37 | Everybody's Fine | - | - | - | $433 | 5 | $55,409 | Jan 28 | Walt Disney Pictures | false |
| 38 | Agora | - | - | - | $426 | 6 | $134,053 | Dec 31 | Italian International Film | false |
| 39 | Tooth Fairy | - | - | - | $331 | 6 | $43,777 | Apr 1 | 20th Century Fox International | false |
| 40 | Green Zone | - | - | - | $112 | 8 | $157,308 | Mar 18 | United International Pictures | false |
| 41 | The Burning Plain | - | - | - | $74 | 5 | $16,311 | Mar 18 | - | false |
