| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Clash of the Titans | - | - | - | $29,211,599 | 468 | $29,242,160 | Apr 2 | Warner Bros. | false |
| 2 | Iron Man 2 | - | - | - | $28,874,701 | 522 | $30,456,328 | Apr 30 | Paramount Pictures International | false |
| 3 | Robin Hood | - | - | - | $16,796,894 | 537 | $23,179,445 | May 14 | Universal Pictures International (UPI) | false |
| 4 | Sex and the City 2 | - | - | - | $8,879,326 | 542 | $33,336,058 | May 28 | Warner Bros. | false |
| 5 | StreetDance 2 | - | - | - | $7,650,831 | 414 | $17,458,740 | May 21 | Vertigo Films | false |
| 6 | StreetDance 3D | - | - | - | $6,252,820 | 414 | $9,941,976 | May 21 | Vertigo Films | false |
| 7 | Prince of Persia: The Sands of Time | - | - | - | $5,807,256 | 484 | $13,514,456 | May 28 | Walt Disney Pictures | false |
| 8 | A Nightmare on Elm Street | - | - | - | $5,062,498 | 357 | $5,062,498 | May 7 | Warner Bros. | false |
| 9 | Furry Vengeance | - | - | - | $4,260,828 | 431 | $4,774,224 | May 7 | Entertainment One | false |
| 10 | Hot Tub Time Machine | - | - | - | $4,161,389 | 397 | $4,161,389 | May 7 | 20th Century Fox International | false |
| 11 | Four Lions | - | - | - | $3,380,997 | 218 | $3,705,570 | May 7 | Optimum Releasing | false |
| 12 | The Back-up Plan | - | - | - | $2,952,219 | 283 | $2,952,219 | May 7 | Sony Pictures Releasing | false |
| 13 | The Last Song | - | - | - | $2,797,888 | 330 | $2,797,888 | Apr 30 | Walt Disney Pictures | false |
| 14 | Date Night | - | - | - | $2,703,789 | 403 | $5,518,097 | Apr 23 | 20th Century Fox International | false |
| 15 | How to Train Your Dragon | - | - | - | $2,343,113 | 490 | $26,488,493 | Apr 2 | Paramount Pictures International | false |
| 16 | The Ghost Writer | - | - | - | $2,031,953 | 343 | $5,719,387 | Apr 16 | Optimum Releasing | false |
| 17 | Dear John | - | - | - | $1,777,192 | 415 | $7,918,385 | Apr 16 | Paramount Pictures International | false |
| 18 | Tooth Fairy | - | - | - | $1,221,291 | 417 | $6,165,210 | Feb 12 | 20th Century Fox International | false |
| 19 | Housefull | - | - | - | $808,480 | 54 | $808,480 | Apr 30 | Eros Worldwide | false |
| 20 | Bad Lieutenant: Port of Call New Orleans | - | - | - | $770,020 | 129 | $770,020 | May 21 | Lionsgate | false |
| 21 | Kites | - | - | - | $679,530 | 70 | $679,530 | May 21 | - | false |
| 22 | Space Chimps 2: Zartog Strikes Back | - | - | - | $628,625 | 404 | $2,318,090 | May 28 | Entertainment Film Distributors | false |
| 23 | Kick-Ass | - | - | - | $583,837 | 424 | $16,763,505 | Apr 2 | Universal Pictures International (UPI) | false |
| 24 | The Losers | - | - | - | $566,548 | 238 | $1,284,442 | May 28 | Optimum Releasing | false |
| 25 | Nanny McPhee Returns | - | - | - | $279,931 | 529 | $23,571,491 | Mar 26 | Universal Pictures International (UPI) | false |
| 26 | It's a Wonderful Afterlife | - | - | - | $267,751 | 294 | $1,243,650 | Apr 2 | Icon Film Distribution Australia | false |
| 27 | The Disappearance of Alice Creed | - | - | - | $217,478 | 67 | $217,478 | Apr 30 | - | false |
| 28 | Alice in Wonderland | - | - | - | $213,919 | 533 | $64,437,055 | Mar 5 | Walt Disney Pictures | false |
| 29 | The Joneses | - | - | - | $169,321 | 217 | $786,455 | Apr 23 | Entertainment One | false |
| 30 | Cemetery Junction | - | - | - | $115,475 | 330 | $2,030,778 | Apr 16 | Sony Pictures Releasing | false |
| 31 | [Rec]² | - | - | - | $101,716 | 50 | $101,716 | May 28 | Entertainment One | false |
| 32 | Cop Out | - | - | - | $94,051 | 127 | $94,051 | May 21 | Warner Bros. | false |
