| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Alice in Wonderland | - | - | - | $17,175,899 | 567 | $28,360,362 | Apr 23 | Walt Disney Pictures | false |
| 2 | Iron Man 2 | - | - | - | $15,484,378 | 626 | $15,835,025 | Apr 30 | Paramount Pictures International | false |
| 3 | Clash of the Titans | - | - | - | $8,859,361 | 554 | $16,238,888 | May 21 | Warner Bros. | false |
| 4 | Robin Hood | - | - | - | $6,350,855 | 413 | $7,953,519 | May 14 | Universal Pictures International (UPI) | false |
| 5 | Chico Xavier | - | - | - | $3,022,047 | 340 | $17,229,064 | Apr 2 | Sony Pictures Releasing | false |
| 6 | A Nightmare on Elm Street | - | - | - | $1,531,380 | 154 | $1,525,642 | May 7 | Warner Bros. | false |
| 7 | Whatever Works | - | - | - | $1,029,584 | 30 | $1,591,880 | Apr 30 | - | false |
| 8 | Sex and the City 2 | - | - | - | $1,007,434 | 216 | $3,185,351 | May 28 | Warner Bros. | false |
| 9 | The Bounty Hunter | - | - | - | $874,568 | 137 | $3,284,719 | Apr 16 | Sony Pictures Releasing | false |
| 10 | The Spy Next Door 2010 Re-release | - | - | - | $613,047 | 92 | $647,533 | May 7 | - | false |
| 11 | The Two Deaths of Quincas Wateryell | - | - | - | $605,671 | 107 | $1,212,639 | May 21 | Walt Disney Pictures | false |
| 12 | Chloe | - | - | - | $496,912 | 62 | $573,541 | May 14 | PlayArte Pictures | false |
| 13 | Date Night | - | - | - | $493,580 | 176 | $3,802,943 | Apr 9 | 20th Century Fox International | false |
| 14 | The Best Things in the World | - | - | - | $290,407 | 152 | $1,214,499 | Apr 16 | Warner Bros. | false |
| 15 | Furry Vengeance | - | - | - | $256,463 | 63 | $407,413 | May 21 | Paris Filmes | false |
| 16 | The Secret in Their Eyes | - | - | - | $242,050 | 24 | $1,805,523 | Feb 26 | Europa Filmes | false |
| 17 | Dear John | - | - | - | $174,709 | 33 | $258,261 | May 7 | Sony Pictures Releasing | false |
| 18 | The Ghost Writer | - | - | - | $164,587 | 30 | $728,417 | May 28 | Paris Filmes | false |
| 19 | The Girl with the Dragon Tattoo | - | - | - | $162,113 | 33 | $173,348 | May 14 | - | false |
| 20 | Segurança Nacional | - | - | - | $131,300 | 37 | $131,300 | May 7 | Europa Filmes | false |
| 21 | The Road | - | - | - | $112,101 | 54 | $312,953 | Apr 23 | Paris Filmes | false |
| 22 | The Imaginarium of Doctor Parnassus | - | - | - | $102,919 | 6 | $166,138 | May 7 | Sony Pictures Releasing | false |
| 23 | Frozen | - | - | - | $93,187 | 52 | $251,715 | May 28 | PlayArte Pictures | false |
| 24 | Green Zone 2010 Re-release | - | - | - | $89,693 | 51 | $508,137 | Apr 16 | Paramount Pictures International | false |
| 25 | Shutter Island | - | - | - | $68,082 | 192 | $4,834,195 | Mar 12 | Paramount Pictures International | false |
| 26 | The Blind Side | - | - | - | $51,522 | 115 | $3,004,286 | Mar 19 | Warner Bros. | false |
| 27 | The Book of Eli | - | - | - | $49,030 | 195 | $4,470,700 | Mar 19 | Sony Pictures Releasing | false |
| 28 | Before the World Ends | - | - | - | $48,112 | 13 | $92,934 | May 14 | - | false |
| 29 | Old Dogs | - | - | - | $38,880 | 49 | $632,898 | Apr 2 | Walt Disney Pictures | false |
| 30 | From Paris with Love | - | - | - | $38,068 | 200 | $1,311,891 | Apr 9 | PlayArte Pictures | false |
| 31 | Mary and Max | - | - | - | $36,816 | 18 | $119,079 | Apr 16 | PlayArte Pictures | false |
| 32 | Stolen Dreams | - | - | - | $30,005 | 27 | $88,222 | Apr 30 | Europa Filmes | false |
| 33 | How to Train Your Dragon | - | - | - | $29,040 | 384 | $11,483,006 | Mar 26 | Paramount Pictures International | false |
| 34 | The Goods: Live Hard, Sell Hard | - | - | - | $26,438 | 24 | $39,898 | May 28 | Europa Filmes | false |
| 35 | Did You Hear About the Morgans? | - | - | - | $24,055 | 61 | $594,219 | Mar 26 | Sony Pictures Releasing | false |
| 36 | The Box | - | - | - | $22,733 | 51 | $506,081 | Mar 26 | - | false |
| 37 | Extract | - | - | - | $22,580 | 18 | $22,580 | May 14 | Paris Filmes | false |
| 38 | Blue Eyes | - | - | - | $20,925 | 20 | $37,470 | May 28 | - | false |
| 39 | Case 39 | - | - | - | $17,500 | 143 | $1,046,012 | Apr 9 | Paramount Pictures International | false |
| 40 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $11,644 | 302 | $9,290,334 | Feb 12 | 20th Century Fox International | false |
| 41 | The Hurt Locker | - | - | - | $8,629 | 62 | $820,754 | Feb 5 | - | false |
| 42 | It's Complicated | - | - | - | $8,311 | 178 | $4,694,495 | Feb 26 | Universal Pictures International (UPI) | false |
| 43 | High School Musical: O Desafio | - | - | - | $6,830 | 203 | $1,149,290 | Feb 5 | Walt Disney Pictures | false |
| 44 | The Men Who Stare at Goats | - | - | - | $6,780 | 10 | $139,183 | Mar 26 | Sony Pictures Releasing | false |
| 45 | Valentine's Day | - | - | - | $4,279 | 160 | $4,405,954 | Feb 19 | Warner Bros. | false |
| 46 | An Education | - | - | - | $4,137 | 13 | $337,832 | Feb 19 | Sony Pictures Releasing | false |
| 47 | Remember Me | - | - | - | $2,126 | 153 | $1,980,250 | Mar 12 | Paris Filmes | false |
| 48 | Easy Virtue | - | - | - | $1,685 | 6 | $201,042 | Oct 23 | Sony Pictures Releasing | false |
| 49 | The Princess and the Frog | - | - | - | $1,346 | 205 | $4,075,122 | Dec 11 | Walt Disney Pictures | false |
| 50 | Brooklyn's Finest | - | - | - | $1,142 | 117 | $743,109 | Apr 2 | - | false |
| 51 | Zombieland | - | - | - | $911 | 47 | $408,565 | Jan 29 | Sony Pictures Releasing | false |
| 52 | Halloween II | - | - | - | $285 | 52 | $119,658 | Mar 26 | PlayArte Pictures | false |
| 53 | Love Happens | - | - | - | $272 | 134 | $1,194,638 | Mar 5 | PlayArte Pictures | false |
| 54 | Julie & Julia | - | - | - | $46 | 53 | $1,261,620 | Nov 27 | Sony Pictures Releasing | false |
