| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Iron Man 2 | - | - | - | $20,712,402 | 473 | $22,418,342 | Apr 29 | Paramount Pictures International | false |
| 2 | Robin Hood | - | - | - | $12,161,033 | 463 | $15,615,874 | May 13 | Universal Pictures International (UPI) | false |
| 3 | Prince of Persia: The Sands of Time | - | - | - | $2,957,559 | 299 | $8,734,153 | Jul 16 | Buena Vista International | false |
| 4 | Letters to Juliet | - | - | - | $2,858,701 | 228 | $3,809,388 | May 13 | Hoyts Distribution | false |
| 5 | The Kings of Mykonos | - | - | - | $2,837,909 | 203 | $4,243,936 | May 20 | Paramount Pictures International | false |
| 6 | The Back-up Plan | - | - | - | $2,145,562 | 205 | $3,370,015 | May 20 | Sony Pictures Releasing | false |
| 7 | I Love You Too | - | - | - | $1,957,891 | 228 | $1,597,474 | May 6 | Roadshow Films | false |
| 8 | A Nightmare on Elm Street | - | - | - | $1,783,848 | 135 | $2,388,495 | May 20 | Warner Bros. | false |
| 9 | Hot Tub Time Machine | - | - | - | $1,517,023 | 204 | $3,295,878 | Apr 22 | 20th Century Fox International | false |
| 10 | When in Rome | - | - | - | $1,169,431 | 211 | $2,315,091 | Apr 22 | Walt Disney Pictures | false |
| 11 | The Girl with the Dragon Tattoo | - | - | - | $938,493 | 90 | $4,849,540 | Mar 25 | Rialto Distribution | false |
| 12 | Beneath Hill 60 | - | - | - | $886,929 | 164 | $2,600,927 | Apr 15 | Paramount Pictures International | false |
| 13 | Date Night | - | - | - | $864,348 | 304 | $7,543,049 | Apr 8 | 20th Century Fox International | false |
| 14 | Harry Brown | - | - | - | $670,975 | 73 | $1,407,625 | May 20 | Icon Film Distribution Australia | false |
| 15 | StreetDance 2 | - | - | - | $643,852 | 127 | $1,838,689 | May 27 | Paramount Pictures International | false |
| 16 | The Book of Eli | - | - | - | $580,350 | 190 | $3,403,495 | Apr 15 | Sony Pictures Releasing | false |
| 17 | The Concert | - | - | - | $549,235 | 36 | $648,823 | Apr 29 | Hopscotch Films | false |
| 18 | The Losers | - | - | - | $373,845 | 116 | $658,469 | May 27 | Warner Bros. | false |
| 19 | Kick-Ass | - | - | - | $278,385 | 236 | $5,021,226 | Apr 8 | Universal Pictures International (UPI) | false |
| 20 | Soul Kitchen | - | - | - | $274,059 | 13 | $274,059 | May 6 | Sharmill Films | false |
| 21 | Kites | - | - | - | $272,835 | 32 | $272,835 | May 20 | Icon Film Distribution Australia | false |
| 22 | Housefull | - | - | - | $233,701 | 18 | $233,701 | Apr 29 | Eros Worldwide | false |
| 23 | New York, I Love You 2010 Re-release | - | - | - | $189,670 | 15 | $241,528 | May 13 | Madman Entertainment | false |
| 24 | The Secret in Their Eyes | - | - | - | $114,010 | 22 | $643,784 | May 27 | Rialto Distribution | false |
| 25 | The White Ribbon | - | - | - | $111,582 | 9 | $223,747 | May 6 | Paramount Pictures International | false |
| 26 | Animal Kingdom | - | - | - | $95,280 | 78 | $4,350,187 | Jun 3 | Madman Entertainment | false |
| 27 | Dynasty | - | - | - | $92,699 | 2 | $202,719 | May 27 | Warren Miller Entertainment | false |
| 28 | The Last Station 2010 Re-release | - | - | - | $76,675 | 50 | $1,040,696 | Apr 1 | Becker Film Group | false |
| 29 | The Blind Side | - | - | - | $58,430 | 226 | $12,273,902 | Feb 25 | Roadshow Films | false |
| 30 | The Hurt Locker | - | - | - | $57,650 | 76 | $5,226,567 | Feb 18 | Roadshow Films | false |
| 31 | Welcome | - | - | - | $45,996 | 23 | $558,706 | Apr 1 | Palace Films | false |
| 32 | Micmacs | - | - | - | $41,299 | 32 | $820,923 | Apr 1 | Hopscotch Films | false |
| 33 | Badmaash Company | - | - | - | $38,132 | 10 | $38,132 | May 6 | Mind Blowing Films | false |
| 34 | City Island | - | - | - | $35,383 | 11 | $244,252 | May 27 | - | false |
| 35 | Food, Inc. | - | - | - | $32,654 | 8 | $34,479 | May 20 | Roadshow Films | false |
| 36 | Fish Tank | - | - | - | $27,813 | 8 | $27,813 | May 27 | Paramount Pictures International | false |
| 37 | The Last Song | - | - | - | $18,463 | 234 | $6,073,470 | Apr 1 | Walt Disney Pictures | false |
| 38 | Love, Lust & Lies | - | - | - | $18,323 | 5 | $18,323 | May 13 | - | false |
| 39 | I, Don Giovanni | - | - | - | $15,640 | 11 | $15,640 | May 6 | Potential Films | false |
| 40 | Ghosts of the Abyss 2010 Re-release | - | - | - | $10,651 | 1 | $5,428,537 | May 13 | IMAX | false |
| 41 | Clash of the Titans | - | - | - | $10,604 | 351 | $17,033,579 | Apr 1 | Warner Bros. | false |
| 42 | The Stoning of Soraya M. | - | - | - | $8,140 | 5 | $8,140 | May 27 | Accent Film Entertainment | false |
| 43 | Ekam: Son of Soil | - | - | - | $4,919 | 4 | $4,919 | May 6 | - | false |
| 44 | The Other Man | - | - | - | $4,274 | 41 | $4,274 | May 13 | Roadshow Films | false |
| 45 | Savages Crossing | - | - | - | $3,928 | 5 | $3,928 | May 13 | - | false |
| 46 | Playing for Charlie | - | - | - | $2,367 | 1 | $2,367 | May 6 | - | false |
| 47 | Leap Year | - | - | - | $1,503 | 10 | $1,503 | May 27 | Roadshow Films | false |
| 48 | Hubble | - | - | - | $1,103 | 22 | $1,682,863 | - | IMAX | false |
