| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Angels & Demons | - | - | - | $211,263 | 7 | $305,510 | May 13 | Sony Pictures Releasing | false |
| 2 | X-Men Origins: Wolverine | - | - | - | $61,311 | 4 | $67,435 | Apr 29 | - | false |
| 3 | 17 Again | - | - | - | $59,003 | 3 | $95,570 | May 8 | - | false |
| 4 | Night at the Museum: Battle of the Smithsonian | - | - | - | $51,843 | 4 | $117,244 | May 22 | - | false |
| 5 | The Boat That Rocked | - | - | - | $41,536 | 3 | $60,077 | May 1 | - | false |
| 6 | I Love You, Man | - | - | - | $35,690 | 3 | $64,090 | Apr 24 | - | false |
| 7 | Monsters vs. Aliens | - | - | - | $31,177 | 8 | $130,366 | Apr 3 | - | false |
| 8 | Star Trek | - | - | - | $30,967 | 3 | $34,542 | May 8 | - | false |
| 9 | Fast & Furious | - | - | - | $22,693 | 4 | $222,074 | Apr 3 | - | false |
| 10 | Knowing | - | - | - | $22,129 | 2 | $83,546 | Apr 10 | ACME | false |
| 11 | Crank: High Voltage | - | - | - | $20,812 | 3 | $80,693 | Apr 17 | ACME | false |
| 12 | Paul Blart: Mall Cop | - | - | - | $16,320 | 3 | $40,733 | Apr 17 | Sony Pictures Releasing | false |
| 13 | The Haunting in Connecticut | - | - | - | $14,922 | 1 | $16,651 | May 8 | ACME | false |
| 14 | Hannah Montana: The Movie | - | - | - | $13,987 | 2 | $20,559 | May 15 | - | false |
| 15 | Taken | - | - | - | $13,523 | 3 | $13,523 | May 1 | ACME | false |
| 16 | Dark Planet: Rebellion | - | - | - | $10,263 | 2 | $25,289 | Apr 24 | ACME | false |
| 17 | The Tale of Despereaux | - | - | - | $10,157 | 7 | $79,979 | May 29 | - | false |
| 18 | Mazie laupitaji | - | - | - | $9,621 | 3 | $79,682 | Mar 27 | ACME | false |
| 19 | Newsmakers | - | - | - | $9,021 | 1 | $12,151 | May 15 | - | false |
| 20 | Slumdog Millionaire | - | - | - | $5,318 | 2 | $232,768 | Feb 27 | ACME | false |
| 21 | State of Play | - | - | - | $4,631 | 2 | $22,114 | Apr 17 | - | false |
| 22 | Observe and Report | - | - | - | $3,138 | 2 | $14,476 | May 29 | - | false |
| 23 | New in Town | - | - | - | $1,701 | 2 | $35,208 | Apr 10 | ACME | false |
| 24 | Confessions of a Shopaholic | - | - | - | $1,165 | 3 | $63,356 | Mar 27 | - | false |
