| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Angels & Demons | - | - | - | $119,580 | 7 | $189,627 | May 14 | Sony Pictures Releasing | false |
| 2 | X-Men Origins: Wolverine | - | - | - | $74,998 | 6 | $83,627 | Apr 30 | 20th Century Fox International | false |
| 3 | Terminator Salvation | - | - | - | $57,766 | 4 | $88,551 | May 21 | - | false |
| 4 | Knowing | - | - | - | $51,455 | 6 | $116,103 | Apr 16 | Jaguar Film International Distribution | false |
| 5 | I Love You, Man | - | - | - | $43,802 | 6 | $75,374 | May 28 | United International Pictures | false |
| 6 | Night at the Museum: Battle of the Smithsonian | - | - | - | $41,091 | 6 | $74,343 | May 21 | 20th Century Fox International | false |
| 7 | Duplicity | - | - | - | $40,839 | 7 | $127,379 | Apr 16 | United International Pictures | false |
| 8 | Coraline | - | - | - | $34,339 | 7 | $52,747 | May 14 | United International Pictures | false |
| 9 | The Uninvited | - | - | - | $33,507 | 6 | $34,031 | Apr 30 | United International Pictures | false |
| 10 | Paul Blart: Mall Cop | - | - | - | $30,157 | 5 | $53,793 | Apr 23 | Sony Pictures Releasing | false |
| 11 | Monsters vs. Aliens | - | - | - | $28,264 | 7 | $150,472 | Apr 2 | United International Pictures | false |
| 12 | Fast & Furious | - | - | - | $25,847 | 8 | $236,939 | Apr 9 | United International Pictures | false |
| 13 | Hannah Montana: The Movie | - | - | - | $25,491 | 6 | $133,756 | Apr 9 | Walt Disney Pictures | false |
| 14 | He's Just Not That Into You | - | - | - | $24,706 | 4 | $98,577 | Apr 9 | - | false |
| 15 | Defiance | - | - | - | $22,294 | 5 | $31,748 | May 14 | - | false |
| 16 | State of Play | - | - | - | $20,362 | 7 | $80,416 | May 28 | United International Pictures | false |
| 17 | Star Trek | - | - | - | $16,226 | 6 | $16,226 | May 7 | United International Pictures | false |
| 18 | How to Lose Friends & Alienate People | - | - | - | $12,686 | 3 | $12,686 | Apr 30 | - | false |
| 19 | New in Town | - | - | - | $11,641 | 5 | $17,993 | May 21 | - | false |
| 20 | It's Alive | - | - | - | $11,385 | 5 | $24,261 | Apr 23 | Italian International Film | false |
| 21 | Charbel | - | - | - | $10,995 | 6 | $314,871 | Feb 5 | Italian International Film | false |
| 22 | Silina | - | - | - | $10,633 | 9 | $106,168 | Mar 26 | Prime Pictures | false |
| 23 | Ramadan Mabrouk Abu Elalamain Hamouda | - | - | - | $8,129 | 7 | $51,670 | Apr 9 | - | false |
| 24 | Harold & Kumar Escape from Guantanamo Bay | - | - | - | $7,533 | 4 | $7,533 | May 7 | Joseph Chacra & Sons | false |
| 25 | Revolver 2007 Re-release | - | - | - | $6,975 | 6 | $7,691 | May 14 | Italian International Film | false |
| 26 | Frozen River | - | - | - | $6,903 | 3 | $7,610 | May 7 | Prime Pictures | false |
| 27 | Shola Cohen | - | - | - | $6,596 | 6 | $14,942 | Apr 9 | - | false |
| 28 | Inkheart | - | - | - | $6,321 | 5 | $6,321 | May 7 | Joseph Chacra & Sons | false |
| 29 | 12 Rounds | - | - | - | $4,329 | 6 | $28,844 | Apr 16 | 20th Century Fox International | false |
| 30 | Skirt Day | - | - | - | $3,449 | 3 | $5,508 | May 21 | Prime Pictures | false |
| 31 | Crossing Over | - | - | - | $3,203 | 5 | $49,356 | Mar 26 | Italian International Film | false |
| 32 | The Reader | - | - | - | $2,933 | 6 | $86,560 | Mar 12 | Italian International Film | false |
| 33 | Finding Amanda | - | - | - | $2,692 | 5 | $7,862 | May 28 | Italian International Film | false |
| 34 | Confessions of a Shopaholic | - | - | - | $2,263 | 6 | $104,508 | Feb 26 | Walt Disney Pictures | false |
| 35 | Race to Witch Mountain | - | - | - | $2,161 | 7 | $47,993 | Mar 12 | Walt Disney Pictures | false |
| 36 | Crusade in Jeans 2008 Re-release | - | - | - | $1,842 | 5 | $2,319 | May 21 | - | false |
| 37 | Boogeyman 2 | - | - | - | $1,704 | 3 | $3,748 | May 28 | - | false |
| 38 | My Mom's New Boyfriend | - | - | - | $1,279 | 4 | $61,575 | Mar 19 | - | false |
| 39 | Hunger | - | - | - | $924 | 1 | $6,263 | Apr 16 | Prime Pictures | false |
| 40 | The Wrestler | - | - | - | $753 | 4 | $10,013 | Apr 9 | Italian International Film | false |
| 41 | The Class | - | - | - | $586 | 2 | $5,958 | Apr 23 | - | false |
| 42 | The Last Deadly Mission | - | - | - | $286 | 5 | $3,002 | Apr 23 | - | false |
| 43 | Hotel for Dogs | - | - | - | $127 | 7 | $38,920 | Mar 19 | United International Pictures | false |
