| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Angels & Demons | - | - | - | $15,582,952 | 699 | $21,944,084 | May 15 | Sony Pictures Releasing | false |
| 2 | X-Men Origins: Wolverine | - | - | - | $10,227,046 | 476 | $11,967,909 | May 1 | 20th Century Fox International | false |
| 3 | Hannah Montana: The Movie | - | - | - | $7,935,883 | 387 | $9,219,841 | May 8 | Walt Disney Pictures | false |
| 4 | Brain Drain | - | - | - | $5,931,806 | 255 | $9,868,246 | Apr 24 | 20th Century Fox International | false |
| 5 | Night at the Museum: Battle of the Smithsonian | - | - | - | $4,825,442 | 503 | $8,925,816 | May 22 | 20th Century Fox International | false |
| 6 | Star Trek | - | - | - | $3,555,900 | 400 | $3,995,497 | May 8 | Paramount Pictures International | false |
| 7 | State of Play | - | - | - | $2,165,901 | 322 | $6,298,330 | Apr 17 | United International Pictures | false |
| 8 | The Girl with the Dragon Tattoo | - | - | - | $1,930,159 | 283 | $13,727,644 | May 29 | Vértigo Films | false |
| 9 | Last Chance Harvey | - | - | - | $1,893,664 | 147 | $2,341,564 | May 8 | United International Pictures | false |
| 10 | 17 Again | - | - | - | $1,712,222 | 304 | $1,924,817 | Apr 30 | TriPictures | false |
| 11 | Gran Torino | - | - | - | $1,609,148 | 263 | $19,038,938 | Mar 6 | Warner Bros. | false |
| 12 | Monsters vs. Aliens | - | - | - | $1,581,742 | 538 | $14,174,228 | Apr 3 | Paramount Pictures International | false |
| 13 | The Young Victoria | - | - | - | $1,565,122 | 151 | $1,812,249 | Apr 30 | Aurum Films | false |
| 14 | Race to Witch Mountain | - | - | - | $1,470,614 | 300 | $5,155,564 | Apr 17 | Walt Disney Pictures | false |
| 15 | The International | - | - | - | $1,301,702 | 230 | $2,523,847 | Apr 24 | Sony Pictures Releasing | false |
| 16 | Fly Me to the Moon 3D | - | - | - | $844,622 | 152 | $938,770 | May 8 | TriPictures | false |
| 17 | Fighting | - | - | - | $785,177 | 179 | $908,527 | May 15 | United International Pictures | false |
| 18 | Knowing | - | - | - | $719,141 | 330 | $6,612,965 | Apr 8 | DeAPlaneta | false |
| 19 | Good | - | - | - | $709,153 | 84 | $1,186,571 | May 22 | DeAPlaneta | false |
| 20 | Slumdog Millionaire | - | - | - | $678,945 | 253 | $14,887,637 | Feb 13 | Filmax | false |
| 21 | The Uninvited | - | - | - | $559,623 | 211 | $1,597,235 | May 22 | Paramount Pictures International | false |
| 22 | Let the Right One In | - | - | - | $558,475 | 65 | $1,304,820 | Apr 17 | Karma Films | false |
| 23 | Road to Santiago | - | - | - | $491,905 | 232 | $3,845,148 | Apr 8 | Warner Bros. | false |
| 24 | Ponyo | - | - | - | $379,969 | 109 | $691,812 | Apr 24 | Aurum Films | false |
| 25 | Seraphine | - | - | - | $364,401 | 30 | $566,810 | May 8 | Golem Distribución | false |
| 26 | Fast & Furious | - | - | - | $356,621 | 333 | $8,747,242 | Apr 3 | United International Pictures | false |
| 27 | Mid-August Lunch | - | - | - | $352,437 | 31 | $1,272,844 | May 22 | Alta Films | false |
| 28 | A Summer in Genoa | - | - | - | $339,164 | 55 | $422,673 | May 8 | Wanda Visión S.A. | false |
| 29 | Bedtime Stories | - | - | - | $292,195 | 400 | $6,753,174 | Mar 6 | Walt Disney Pictures | false |
| 30 | A Good Man | - | - | - | $255,750 | 88 | $279,797 | Apr 30 | Alta Films | false |
| 31 | The Reader | - | - | - | $222,578 | 210 | $6,648,318 | Feb 13 | On Pictures | false |
| 32 | Rabbit Without Ears | - | - | - | $222,305 | 101 | $246,624 | Apr 30 | Warner Bros. | false |
| 33 | Carmo, Hit the Road | - | - | - | $209,385 | 26 | $226,713 | May 15 | - | false |
| 34 | The Visitor | - | - | - | $205,490 | 52 | $1,514,424 | Mar 13 | Karma Films | false |
| 35 | The Shame | - | - | - | $204,880 | 47 | $232,548 | Apr 30 | Avalon | false |
| 36 | 25 Carat | - | - | - | $185,572 | 26 | $277,723 | Apr 24 | Golem Distribución | false |
| 37 | Welcome to the Sticks | - | - | - | $136,738 | 159 | $4,921,136 | Jan 9 | Wanda Visión S.A. | false |
| 38 | Dragonball Evolution | - | - | - | $128,772 | 348 | $2,979,059 | Apr 8 | 20th Century Fox International | false |
| 39 | Insignificant Things | - | - | - | $123,791 | 35 | $316,085 | May 15 | Notro Films | false |
| 40 | Watchmen | - | - | - | $122,694 | 426 | $4,316,109 | Mar 6 | Paramount Pictures International | false |
| 41 | Deception | - | - | - | $114,963 | 235 | $2,625,481 | Apr 3 | TriPictures | false |
| 42 | Hotel for Dogs | - | - | - | $113,962 | 220 | $2,369,928 | Mar 13 | Paramount Pictures International | false |
| 43 | Marley & Me | - | - | - | $113,514 | 304 | $3,762,236 | Mar 20 | 20th Century Fox International | false |
| 44 | The Duchess | - | - | - | $110,646 | 160 | $1,487,262 | Apr 3 | Vértigo Films | false |
| 45 | Duplicity | - | - | - | $106,392 | 301 | $3,394,289 | Mar 20 | United International Pictures | false |
| 46 | Smother | - | - | - | $101,599 | 121 | $340,018 | Apr 24 | Manga Entertainment | false |
| 47 | Esperpentos | - | - | - | $95,289 | 2 | $181,045 | Apr 24 | - | false |
| 48 | Little Ashes | - | - | - | $73,115 | 29 | $104,991 | May 8 | - | false |
| 49 | Empties | - | - | - | $72,272 | 21 | $146,373 | May 22 | Karma Films | false |
| 50 | Cataluña Espanya | - | - | - | $68,171 | 13 | $132,629 | Apr 24 | - | false |
| 51 | Sex, Party & Lies | - | - | - | $67,931 | 240 | $5,697,683 | Mar 27 | Sony Pictures Releasing | false |
| 52 | Confessions of a Shopaholic | - | - | - | $66,619 | 270 | $1,923,368 | Mar 27 | Walt Disney Pictures | false |
| 53 | Paris 36 | - | - | - | $63,769 | 100 | $732,328 | Apr 8 | Aurum Films | false |
| 54 | Sicko 2009 Re-release | - | - | - | $62,490 | 20 | $70,264 | Apr 30 | - | false |
| 55 | El libro de las aguas | - | - | - | $60,499 | 15 | $292,773 | Nov 13 | Independent Films | false |
| 56 | Paraiso Travel | - | - | - | $58,993 | 27 | $68,767 | May 1 | Filmax | false |
| 57 | The Boat That Rocked | - | - | - | $58,371 | 47 | $212,834 | May 29 | United International Pictures | false |
| 58 | The Class | - | - | - | $57,824 | 65 | $1,876,570 | Jan 16 | Golem Distribución | false |
| 59 | The Burning Plain | - | - | - | $55,824 | 101 | $1,025,130 | Mar 13 | United International Pictures | false |
| 60 | Possibility of an Island | - | - | - | $50,694 | 6 | $54,414 | May 15 | - | false |
| 61 | L'auberge rouge 2009 Re-release | - | - | - | $43,979 | 28 | $48,549 | May 15 | Filmax | false |
| 62 | Female Agents | - | - | - | $41,778 | 63 | $562,283 | Apr 8 | Manga Entertainment | false |
| 63 | Around the World for Free | - | - | - | $36,614 | 118 | $42,551 | Apr 24 | Barton Films | false |
| 64 | The Wrestler | - | - | - | $31,022 | 155 | $1,113,996 | Feb 20 | United International Pictures | false |
| 65 | Tricks | - | - | - | $28,012 | 6 | $44,599 | Apr 24 | Sherlock Films | false |
| 66 | Blindness | - | - | - | $27,353 | 120 | $828,898 | Mar 13 | Notro Films | false |
| 67 | Sukalde kontuak | - | - | - | $27,141 | 31 | $34,004 | May 22 | Barton Films | false |
| 68 | Waltz with Bashir | - | - | - | $25,415 | 34 | $282,886 | Feb 20 | Golem Distribución | false |
| 69 | Cherry Blossoms | - | - | - | $23,790 | 35 | $356,041 | Mar 6 | Wanda Visión S.A. | false |
| 70 | Salt of This Sea | - | - | - | $22,562 | 6 | $63,361 | Apr 17 | Alta Films | false |
| 71 | Rudo y Cursi | - | - | - | $21,061 | 116 | $118,053 | Mar 27 | United International Pictures | false |
| 72 | Flash of Genius | - | - | - | $19,313 | 12 | $20,965 | May 8 | United International Pictures | false |
| 73 | Notorious | - | - | - | $18,809 | 30 | $38,793 | May 8 | 20th Century Fox International | false |
| 74 | A Christmas Tale | - | - | - | $18,303 | 8 | $171,096 | Mar 27 | Alta Films | false |
| 75 | How I Celebrated the End of the World 2009 Re-release | - | - | - | $18,004 | 7 | $26,423 | May 22 | - | false |
| 76 | Black Listed | - | - | - | $17,793 | 63 | $291,074 | Apr 3 | Filmax | false |
| 77 | The Beautiful Person | - | - | - | $16,598 | 9 | $33,436 | May 22 | - | false |
| 78 | Henry Poole Is Here | - | - | - | $15,443 | 31 | $29,198 | May 29 | Filmax | false |
| 79 | Control | - | - | - | $15,175 | 20 | $149,862 | Apr 8 | Avalon | false |
| 80 | The Fish Child | - | - | - | $14,648 | 14 | $39,063 | Apr 24 | Wanda Visión S.A. | false |
| 81 | The Good Life | - | - | - | $13,600 | 9 | $87,575 | Apr 3 | Alta Films | false |
| 82 | Flight of the Red Balloon | - | - | - | $12,930 | 6 | $52,341 | Apr 17 | Notro Films | false |
| 83 | The Secret Life of Bees | - | - | - | $12,920 | 46 | $190,372 | Mar 27 | 20th Century Fox International | false |
| 84 | Una cierta verdad | - | - | - | $11,660 | 3 | $11,660 | May 8 | Notro Films | false |
| 85 | Últimos testigos | - | - | - | $11,612 | 3 | $11,612 | May 8 | - | false |
| 86 | Two-Legged Horse | - | - | - | $8,478 | 5 | $13,753 | May 22 | Golem Distribución | false |
| 87 | Where Is Winky's Horse? 2008 Re-release | - | - | - | $8,404 | 13 | $11,170 | May 15 | - | false |
| 88 | The Bottle | - | - | - | $7,691 | 23 | $36,918 | Apr 17 | - | false |
| 89 | Man on Wire | - | - | - | $5,095 | 29 | $57,262 | Apr 17 | Vértigo Films | false |
| 90 | Liverpool | - | - | - | $4,345 | 5 | $14,862 | Apr 24 | Sagrera TV | false |
| 91 | Billu | - | - | - | $3,835 | 3 | $4,759 | May 15 | - | false |
| 92 | Flower of Seduction | - | - | - | $3,479 | 16 | $19,753 | Apr 17 | - | false |
| 93 | Paul Blart: Mall Cop | - | - | - | $3,141 | 30 | $105,532 | Mar 27 | Sony Pictures Releasing | false |
| 94 | Underworld: Rise of the Lycans | - | - | - | $2,802 | 297 | $3,548,025 | Mar 13 | Sony Pictures Releasing | false |
| 95 | La mala | - | - | - | $2,236 | 6 | $5,780 | May 29 | - | false |
| 96 | The Pink Panther 2 | - | - | - | $1,478 | 397 | $3,806,443 | Feb 27 | Sony Pictures Releasing | false |
| 97 | Cloud 9 | - | - | - | $1,213 | 27 | $155,768 | Mar 20 | Baditri | false |
| 98 | The Curious Case of Benjamin Button | - | - | - | $929 | 461 | $16,210,146 | Feb 6 | Warner Bros. | false |
| 99 | Beverly Hills Chihuahua | - | - | - | $723 | 300 | $7,963,722 | Feb 6 | Walt Disney Pictures | false |
| 100 | Return to Hansala | - | - | - | $723 | 39 | $143,567 | Mar 27 | Wanda Visión S.A. | false |
| 101 | Let it Rain | - | - | - | $638 | 29 | $257,516 | Feb 27 | Festival Films S.L. | false |
| 102 | Doubt | - | - | - | $520 | 132 | $3,535,903 | Jan 30 | Walt Disney Pictures | false |
| 103 | Revolutionary Road | - | - | - | $182 | 261 | $5,580,919 | Jan 23 | Paramount Pictures International | false |
