| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Angels & Demons | - | - | - | $29,915,121 | 1,092 | $47,070,399 | May 13 | Sony Pictures Releasing | false |
| 2 | Star Trek | - | - | - | $10,784,086 | 688 | $12,798,139 | May 7 | Paramount Pictures International | false |
| 3 | X-Men Origins: Wolverine | - | - | - | $8,871,525 | 692 | $9,633,797 | Apr 29 | 20th Century Fox International | false |
| 4 | Night at the Museum: Battle of the Smithsonian | - | - | - | $7,927,192 | 748 | $19,146,827 | May 21 | 20th Century Fox International | false |
| 5 | 17 Again | - | - | - | $3,520,764 | 294 | $5,556,424 | May 14 | Warner Bros. | false |
| 6 | Slumdog Millionaire | - | - | - | $3,247,563 | 432 | $19,188,873 | Mar 19 | Prokino Filmverleih | false |
| 7 | Duplicity | - | - | - | $2,493,327 | 277 | $2,789,468 | Apr 30 | Universal Pictures International (UPI) | false |
| 8 | Twilight | - | - | - | $1,788,427 | 640 | $23,734,298 | Jan 15 | Concorde Filmverleih | false |
| 9 | Beverly Hills Chihuahua | - | - | - | $1,702,155 | 312 | $2,425,811 | Apr 30 | Walt Disney Pictures | false |
| 10 | Crank: High Voltage | - | - | - | $1,628,918 | 405 | $6,890,754 | Apr 16 | Universum Film (UFA) | false |
| 11 | Ghosts of Girlfriends Past | - | - | - | $1,605,588 | 328 | $6,957,884 | May 28 | Walt Disney Pictures | false |
| 12 | Fast & Furious | - | - | - | $1,345,171 | 637 | $15,423,592 | Apr 2 | Universal Pictures International (UPI) | false |
| 13 | My Bloody Valentine | - | - | - | $1,170,770 | 69 | $3,135,001 | May 20 | Kinowelt Filmverleih | false |
| 14 | Monsters vs. Aliens | - | - | - | $1,143,951 | 715 | $6,874,432 | Apr 2 | Paramount Pictures International | false |
| 15 | Paul Blart: Mall Cop | - | - | - | $1,114,852 | 509 | $12,900,472 | Mar 26 | Sony Pictures Releasing | false |
| 16 | The Reader | - | - | - | $1,092,990 | 490 | $20,544,884 | Feb 26 | Senator Film | false |
| 17 | Knowing | - | - | - | $1,013,904 | 440 | $4,994,862 | Apr 9 | Concorde Filmverleih | false |
| 18 | The Crocodiles | - | - | - | $971,130 | 450 | $4,452,060 | Mar 26 | Constantin Film | false |
| 19 | Princess Lillifee | - | - | - | $852,211 | 506 | $6,431,914 | Mar 26 | Universum Film (UFA) | false |
| 20 | I Love You, Man | - | - | - | $767,774 | 268 | $1,384,912 | Apr 23 | Paramount Pictures International | false |
| 21 | The Last House on the Left | - | - | - | $745,401 | 150 | $1,160,672 | Jul 30 | Universal Pictures International (UPI) | false |
| 22 | Phantom Pain | - | - | - | $693,304 | 146 | $769,245 | Apr 30 | Warner Bros. | false |
| 23 | Männersache | - | - | - | $628,359 | 502 | $16,813,421 | Mar 19 | Constantin Film | false |
| 24 | Welcome to the Sticks | - | - | - | $626,883 | 321 | $17,147,691 | Oct 30 | Kinowelt Filmverleih | false |
| 25 | Last Chance Harvey | - | - | - | $599,842 | 123 | $2,139,464 | Apr 16 | Concorde Filmverleih | false |
| 26 | I Saw the Sun 2009 Re-release | - | - | - | $587,348 | 70 | $1,555,535 | Apr 16 | - | false |
| 27 | Gran Torino | - | - | - | $580,853 | 157 | $6,371,649 | Mar 5 | Warner Bros. | false |
| 28 | Mid-August Lunch | - | - | - | $537,180 | 59 | $1,030,273 | Apr 30 | Pandora Filmproduktion | false |
| 29 | The First Day of the Rest of Your Life | - | - | - | $502,624 | 63 | $1,024,920 | Apr 23 | Kinowelt Filmverleih | false |
| 30 | The Three Investigators and the Secret of Terror Castle | - | - | - | $501,249 | 386 | $4,137,662 | Mar 19 | Walt Disney Pictures | false |
| 31 | The Boat That Rocked | - | - | - | $460,051 | 497 | $1,821,517 | Apr 16 | Universal Pictures International (UPI) | false |
| 32 | The Uninvited | - | - | - | $411,393 | 101 | $1,253,346 | May 28 | Paramount Pictures International | false |
| 33 | Defiance | - | - | - | $408,632 | 253 | $860,153 | Apr 23 | Constantin Film | false |
| 34 | John Rabe | - | - | - | $378,710 | 127 | $1,241,380 | Mar 12 | Majestic Filmverleih | false |
| 35 | Sunshine Cleaning | - | - | - | $360,977 | 71 | $765,397 | May 21 | Capelight Pictures | false |
| 36 | Lilly the Witch: The Dragon and the Magic Book | - | - | - | $334,734 | 454 | $8,264,019 | Feb 19 | Walt Disney Pictures | false |
| 37 | Hilde | - | - | - | $312,536 | 243 | $3,552,579 | Mar 12 | Warner Bros. | false |
| 38 | Dorfpunks | - | - | - | $245,302 | 43 | $424,773 | Aug 27 | Piffl Medien | false |
| 39 | Effi Briest | - | - | - | $207,860 | 154 | $3,314,400 | Feb 12 | Constantin Film | false |
| 40 | The Limits of Control | - | - | - | $180,705 | 56 | $812,258 | May 28 | TOBIS Film | false |
| 41 | Public Enemy | - | - | - | $173,627 | 32 | $211,125 | May 21 | Senator Film | false |
| 42 | Eldorado | - | - | - | $164,989 | 23 | $225,930 | May 14 | KOOL Filmdistribution | false |
| 43 | The Boy in the Striped Pajamas | - | - | - | $164,209 | 30 | $218,186 | May 7 | Walt Disney Pictures | false |
| 44 | Mesrine: Killer Instinct | - | - | - | $141,913 | 127 | $379,408 | Apr 23 | Senator Film | false |
| 45 | Willi und die Wunder dieser Welt | - | - | - | $138,303 | 197 | $1,928,276 | Mar 5 | MFA+ FilmDistribution | false |
| 46 | Race to Witch Mountain | - | - | - | $107,364 | 310 | $888,041 | Apr 9 | Walt Disney Pictures | false |
| 47 | Il Divo | - | - | - | $99,083 | 32 | $264,251 | Apr 16 | Delphi Filmverleih Produktion | false |
| 48 | Journey to the Center of the Earth | - | - | - | $93,881 | 225 | $1,486,420 | Mar 5 | Warner Bros. | false |
| 49 | The Unborn | - | - | - | $60,770 | 250 | $1,665,286 | Mar 12 | Universal Pictures International (UPI) | false |
| 50 | Boy A | - | - | - | $56,352 | 33 | $56,352 | May 7 | Senator Film | false |
| 51 | Ricky | - | - | - | $45,991 | 45 | $45,991 | May 14 | Concorde Filmverleih | false |
| 52 | The Duchess | - | - | - | $40,534 | 155 | $677,525 | Mar 26 | Kinowelt Filmverleih | false |
| 53 | The Tale of Despereaux | - | - | - | $39,123 | 310 | $803,545 | Mar 19 | Universal Pictures International (UPI) | false |
| 54 | The Forbidden Kingdom | - | - | - | $38,962 | 121 | $344,900 | Apr 16 | Central Film | false |
| 55 | 12 Rounds | - | - | - | $36,256 | 15 | $48,378 | May 28 | 20th Century Fox International | false |
| 56 | Adoration | - | - | - | $30,911 | 34 | $30,911 | May 28 | X Verleih AG | false |
| 57 | Pain of Autumn | - | - | - | $28,977 | 21 | $28,977 | Apr 30 | Kinostar Filmverleih | false |
| 58 | Cadillac Records | - | - | - | $15,932 | 50 | $81,266 | Apr 23 | Sony Pictures Releasing | false |
| 59 | Confessions of a Shopaholic | - | - | - | $12,883 | 426 | $4,418,662 | Mar 12 | Walt Disney Pictures | false |
| 60 | I've Never Been Happier | - | - | - | $9,461 | 37 | $179,876 | Apr 9 | Kinowelt Filmverleih | false |
| 61 | Die Ludolfs - Dankeschön für Italien! | - | - | - | $7,905 | 68 | $203,607 | Apr 9 | Zorro Film | false |
| 62 | Milk | - | - | - | $7,617 | 76 | $1,658,829 | Feb 19 | Constantin Film | false |
| 63 | Rachel Getting Married | - | - | - | $7,252 | 51 | $273,535 | Apr 2 | Sony Pictures Releasing | false |
| 64 | Machan | - | - | - | $3,366 | 8 | $3,366 | May 7 | 20th Century Fox International | false |
