| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | X-Men Origins: Wolverine | - | - | - | $12,169,090 | 575 | $14,135,273 | Apr 30 | 20th Century Fox International | false |
| 2 | Angels & Demons | - | - | - | $9,902,411 | 509 | $13,858,975 | May 15 | Sony Pictures Releasing | false |
| 3 | Night at the Museum: Battle of the Smithsonian | - | - | - | $5,457,587 | 488 | $11,516,835 | May 22 | 20th Century Fox International | false |
| 4 | Diva 2009 Re-release | - | - | - | $4,213,971 | 194 | $8,466,593 | Apr 17 | - | false |
| 5 | Star Trek | - | - | - | $1,730,458 | 275 | $1,907,913 | May 8 | Paramount Pictures International | false |
| 6 | Fast & Furious | - | - | - | $1,554,728 | 226 | $10,348,525 | Apr 3 | Universal Pictures International (UPI) | false |
| 7 | If I Were You 2 | - | - | - | $1,233,480 | 311 | $24,415,116 | Jan 2 | 20th Century Fox International | false |
| 8 | Monsters vs. Aliens | - | - | - | $1,220,184 | 331 | $6,947,463 | Apr 3 | Paramount Pictures International | false |
| 9 | Knowing | - | - | - | $827,708 | 201 | $4,357,618 | Apr 10 | Paris Filmes | false |
| 10 | Garfield's Fun Fest | - | - | - | $629,883 | 113 | $729,560 | Apr 30 | PlayArte Pictures | false |
| 11 | New in Town | - | - | - | $473,136 | 65 | $522,314 | Apr 30 | - | false |
| 12 | Slumdog Millionaire | - | - | - | $368,649 | 185 | $6,215,957 | Mar 6 | Europa Filmes | false |
| 13 | The Haunting in Connecticut | - | - | - | $348,952 | 137 | $1,682,223 | Apr 17 | - | false |
| 14 | He's Just Not That Into You | - | - | - | $346,113 | 145 | $3,693,638 | Mar 27 | PlayArte Pictures | false |
| 15 | Race to Witch Mountain | - | - | - | $314,807 | 108 | $1,249,852 | Apr 17 | Walt Disney Pictures | false |
| 16 | I Hate Valentine's Day | - | - | - | $293,382 | 132 | $834,206 | Apr 24 | PlayArte Pictures | false |
| 17 | Defiance | - | - | - | $282,307 | 42 | $321,534 | May 8 | - | false |
| 18 | Jonas Brothers: The 3D Concert Experience | - | - | - | $279,615 | 50 | $680,392 | May 29 | Walt Disney Pictures | false |
| 19 | I Love You, Man | - | - | - | $259,938 | 75 | $536,762 | Apr 24 | Paramount Pictures International | false |
| 20 | The Invisible Woman | - | - | - | $247,811 | 221 | $11,436,322 | Jun 5 | Warner Bros. | false |
| 21 | Budapest | - | - | - | $243,241 | 39 | $386,929 | May 22 | - | false |
| 22 | Underworld: Rise of the Lycans | - | - | - | $229,121 | 163 | $1,410,880 | Apr 17 | Sony Pictures Releasing | false |
| 23 | Dragonball Evolution | - | - | - | $214,163 | 146 | $1,861,083 | Apr 9 | 20th Century Fox International | false |
| 24 | Che: Part One | - | - | - | $201,213 | 34 | $789,064 | Mar 27 | Europa Filmes | false |
| 25 | Simonal: Ninguém Sabe o Duro que Dei | - | - | - | $180,273 | 24 | $332,619 | May 15 | - | false |
| 26 | Bedtime Stories | - | - | - | $177,993 | 207 | $3,618,106 | Jan 23 | Walt Disney Pictures | false |
| 27 | Gran Torino | - | - | - | $159,345 | 104 | $1,653,661 | Mar 20 | Warner Bros. | false |
| 28 | Lust, Caution | - | - | - | $146,199 | 12 | $299,932 | May 15 | Europa Filmes | false |
| 29 | The Class | - | - | - | $134,519 | 35 | $610,089 | Mar 13 | Imovision | false |
| 30 | Confessions of a Shopaholic | - | - | - | $118,839 | 78 | $812,724 | Apr 10 | Walt Disney Pictures | false |
| 31 | Donkey Xote | - | - | - | $109,867 | 90 | $217,446 | May 29 | - | false |
| 32 | The Reader | - | - | - | $103,056 | 70 | $1,824,947 | Feb 6 | Imagem Filmes | false |
| 33 | Push | - | - | - | $99,145 | 69 | $171,028 | May 29 | Paris Filmes | false |
| 34 | Hotel for Dogs | - | - | - | $98,975 | 130 | $1,868,930 | Feb 20 | Paramount Pictures International | false |
| 35 | The Happy Cricket and the Giant Bugs | - | - | - | $84,305 | 119 | $915,932 | Jan 9 | 20th Century Fox International | false |
| 36 | My Bloody Valentine | - | - | - | $83,588 | 137 | $1,229,646 | Mar 13 | PlayArte Pictures | false |
| 37 | Killshot | - | - | - | $70,383 | 37 | $119,569 | May 29 | PlayArte Pictures | false |
| 38 | The Counterfeiters | - | - | - | $68,559 | 24 | $249,802 | May 29 | Europa Filmes | false |
| 39 | Doubt | - | - | - | $60,946 | 36 | $757,109 | Feb 6 | Walt Disney Pictures | false |
| 40 | Happy-Go-Lucky | - | - | - | $59,335 | 20 | $236,302 | Mar 27 | Imagem Filmes | false |
| 41 | Milk | - | - | - | $54,831 | 50 | $1,012,071 | Feb 20 | Universal Pictures International (UPI) | false |
| 42 | The Unborn | - | - | - | $46,460 | 120 | $873,034 | Mar 20 | Universal Pictures International (UPI) | false |
| 43 | Beverly Hills Chihuahua | - | - | - | $34,821 | 65 | $589,395 | Feb 13 | Walt Disney Pictures | false |
| 44 | Earth | - | - | - | $31,327 | 35 | $97,761 | Apr 22 | Walt Disney Pictures | false |
| 45 | O Menino da Porteira | - | - | - | $22,845 | 270 | $1,871,774 | Mar 6 | Sony Pictures Releasing | false |
| 46 | Personal Effects | - | - | - | $20,730 | 37 | $160,670 | Apr 3 | Imagem Filmes | false |
| 47 | Waltz with Bashir | - | - | - | $19,770 | 9 | $111,235 | Apr 3 | Sony Pictures Releasing | false |
| 48 | Rachel Getting Married | - | - | - | $18,316 | 15 | $334,135 | Feb 13 | Sony Pictures Releasing | false |
| 49 | Crossing Over | - | - | - | $16,727 | 40 | $137,284 | Apr 10 | - | false |
| 50 | Synecdoche, New York | - | - | - | $15,807 | 6 | $80,683 | Apr 17 | - | false |
| 51 | Actresses | - | - | - | $13,581 | 2 | $14,284 | May 1 | Pandora Filmes | false |
| 52 | The Visitor | - | - | - | $12,804 | 12 | $119,343 | Mar 13 | Moviemobz Rain | false |
| 53 | FilmeFobia | - | - | - | $12,048 | 6 | $12,105 | Apr 30 | - | false |
| 54 | The Secrets | - | - | - | $9,867 | 11 | $58,280 | Mar 27 | Paris Filmes | false |
| 55 | Miracle at St. Anna | - | - | - | $9,630 | 4 | $9,821 | Apr 30 | - | false |
| 56 | Ashes of Time | - | - | - | $9,503 | 11 | $27,531 | May 1 | - | false |
| 57 | Katyn | - | - | - | $9,304 | 6 | $45,138 | Apr 3 | Moviemobz Rain | false |
| 58 | W. | - | - | - | $7,528 | 9 | $48,536 | Apr 10 | - | false |
| 59 | Paulo Gracindo - O Bem Amado | - | - | - | $6,225 | 3 | $6,225 | Apr 30 | - | false |
| 60 | Alexandra | - | - | - | $4,918 | 2 | $6,125 | May 1 | - | false |
| 61 | Bolt | - | - | - | $4,600 | 220 | $4,640,182 | Jan 1 | Walt Disney Pictures | false |
| 62 | Frozen River | - | - | - | $4,163 | 6 | $49,510 | Feb 20 | Sony Pictures Releasing | false |
| 63 | A Ilha Da Morte | - | - | - | $1,743 | 4 | $1,773 | May 8 | - | false |
| 64 | Valkyrie | - | - | - | $1,210 | 224 | $4,605,676 | Feb 13 | 20th Century Fox International | false |
| 65 | The Spirit | - | - | - | $1,184 | 76 | $358,180 | Mar 20 | Sony Pictures Releasing | false |
| 66 | Impy's Wonderland | - | - | - | $800 | 14 | $327,790 | Mar 13 | Paris Filmes | false |
| 67 | Yes Man | - | - | - | $431 | 151 | $5,321,595 | Jan 30 | Warner Bros. | false |
| 68 | Surf Adventures 2 - A Busca Continua | - | - | - | $392 | 61 | $206,620 | Mar 27 | Universal Pictures International (UPI) | false |
| 69 | The Code | - | - | - | $372 | 106 | $1,081,542 | Mar 13 | Imagem Filmes | false |
| 70 | The Pink Panther 2 | - | - | - | $342 | 251 | $1,954,340 | Feb 20 | Sony Pictures Releasing | false |
| 71 | The Curious Case of Benjamin Button | - | - | - | $261 | 202 | $8,598,448 | Jan 16 | Warner Bros. | false |
| 72 | The Boy in the Striped Pajamas | - | - | - | $213 | 20 | $327,032 | Dec 12 | Walt Disney Pictures | false |
| 73 | Seven Pounds | - | - | - | $193 | 215 | $4,651,219 | Dec 25 | Sony Pictures Releasing | false |
| 74 | They Killed Sister Dorothy | - | - | - | $144 | 4 | $4,726 | Apr 17 | - | false |
