| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Angels & Demons | - | - | - | $164,263 | 8 | $239,530 | May 14 | Sony Pictures Releasing | false |
| 2 | X-Men Origins: Wolverine | - | - | - | $142,152 | 8 | $147,666 | Apr 30 | 20th Century Fox International | false |
| 3 | Night at the Museum: Battle of the Smithsonian | - | - | - | $86,006 | 9 | $150,284 | May 21 | 20th Century Fox International | false |
| 4 | The Boy in the Striped Pajamas | - | - | - | $30,545 | 3 | $30,545 | Apr 9 | Walt Disney Pictures | false |
| 5 | Star Trek | - | - | - | $29,986 | 6 | $30,804 | May 8 | United International Pictures | false |
| 6 | Race to Witch Mountain | - | - | - | $23,846 | 5 | $111,046 | Mar 26 | Walt Disney Pictures | false |
| 7 | My Bloody Valentine | - | - | - | $21,571 | 2 | $106,046 | Mar 13 | Trade International | false |
| 8 | Confessions of a Shopaholic | - | - | - | $21,559 | 4 | $21,559 | Apr 10 | Walt Disney Pictures | false |
| 9 | Donkey Xote | - | - | - | $16,698 | 2 | $20,713 | Apr 30 | Trade International | false |
| 10 | Jonas Brothers: The 3D Concert Experience | - | - | - | $14,838 | 2 | $22,952 | Apr 23 | Walt Disney Pictures | false |
| 11 | Captivity | - | - | - | $14,586 | 2 | $29,825 | Apr 16 | Trade International | false |
| 12 | Paul Blart: Mall Cop | - | - | - | $11,977 | 5 | $46,703 | Apr 9 | Sony Pictures Releasing | false |
| 13 | Monsters vs. Aliens | - | - | - | $9,937 | 10 | $115,993 | Apr 2 | United International Pictures | false |
| 14 | The Pink Panther 2 | - | - | - | $9,487 | 4 | $20,220 | Apr 23 | Sony Pictures Releasing | false |
| 15 | Fast & Furious | - | - | - | $9,345 | 5 | $23,965 | Apr 3 | United International Pictures | false |
| 16 | The Diving Bell and the Butterfly | - | - | - | $8,963 | 2 | $14,254 | Apr 23 | - | false |
| 17 | Earth | - | - | - | $6,957 | 1 | $12,471 | Apr 22 | Walt Disney Pictures | false |
| 18 | Lassie | - | - | - | $6,514 | 2 | $6,514 | May 7 | Trade International | false |
| 19 | Changeling | - | - | - | $5,895 | 4 | $5,895 | May 21 | United International Pictures | false |
| 20 | He's Just Not That Into You | - | - | - | $5,422 | 3 | $16,740 | Apr 23 | PlayArte Pictures | false |
| 21 | Dragonball Evolution | - | - | - | $4,396 | 8 | $80,306 | Apr 9 | 20th Century Fox International | false |
| 22 | Historias De Vino, Singani Y Alcoba | - | - | - | $3,456 | 6 | $49,445 | Apr 9 | - | false |
| 23 | Lonely Hearts | - | - | - | $3,412 | 1 | $3,412 | May 21 | Trade International | false |
| 24 | Che: Part Two | - | - | - | $3,151 | 3 | $14,884 | May 28 | - | false |
| 25 | Miguel N. El Hombre Detras del Secuestro de Londsdale | - | - | - | $2,506 | 3 | $2,506 | May 14 | - | false |
| 26 | The International | - | - | - | $2,458 | 4 | $18,607 | Apr 16 | Sony Pictures Releasing | false |
| 27 | Clerks II 2009 Re-release | - | - | - | $1,199 | 1 | $1,199 | May 14 | Trade International | false |
| 28 | Leonera | - | - | - | $549 | 1 | $549 | May 21 | - | false |
