| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Angels & Demons | - | - | - | $3,863,336 | 143 | $5,657,219 | May 13 | Sony Pictures Releasing | false |
| 2 | X-Men Origins: Wolverine | - | - | - | $1,284,099 | 102 | $1,573,330 | May 1 | 20th Century Fox International | false |
| 3 | Star Trek | - | - | - | $1,023,661 | 73 | $1,299,547 | May 8 | Universal Pictures International (UPI) | false |
| 4 | Night at the Museum: Battle of the Smithsonian | - | - | - | $973,756 | 107 | $2,357,145 | May 21 | 20th Century Fox International | false |
| 5 | 17 Again | - | - | - | $507,063 | 54 | $849,515 | May 15 | Warner Bros. | false |
| 6 | Hannah Montana: The Movie | - | - | - | $471,807 | 77 | $2,016,441 | May 28 | Walt Disney Pictures | false |
| 7 | Beverly Hills Chihuahua | - | - | - | $395,535 | 73 | $578,983 | Apr 30 | Walt Disney Pictures | false |
| 8 | My Bloody Valentine | - | - | - | $369,429 | 26 | $1,059,834 | May 21 | - | false |
| 9 | Ghosts of Girlfriends Past | - | - | - | $364,841 | 56 | $1,682,181 | May 28 | Warner Bros. | false |
| 10 | Slumdog Millionaire | - | - | - | $359,936 | 70 | $2,581,420 | Mar 19 | Filmladen | false |
| 11 | Duplicity | - | - | - | $322,831 | 48 | $363,836 | Apr 30 | Universal Pictures International (UPI) | false |
| 12 | Journey to the Center of the Earth | - | - | - | $253,651 | 55 | $345,142 | May 1 | Warner Bros. | false |
| 13 | Crank: High Voltage | - | - | - | $215,381 | 37 | $846,591 | Apr 17 | Constantin Film | false |
| 14 | I Love You, Man | - | - | - | $196,602 | 43 | $330,141 | Apr 24 | Universal Pictures International (UPI) | false |
| 15 | Fast & Furious | - | - | - | $194,872 | 81 | $2,766,603 | Apr 3 | Universal Pictures International (UPI) | false |
| 16 | The Bone Man | - | - | - | $184,913 | 84 | $2,796,567 | Mar 6 | Luna Filmverleih | false |
| 17 | Monsters vs. Aliens | - | - | - | $170,944 | 78 | $1,034,672 | Apr 2 | Universal Pictures International (UPI) | false |
| 18 | Paul Blart: Mall Cop | - | - | - | $166,520 | 91 | $2,350,624 | Mar 27 | Sony Pictures Releasing | false |
| 19 | The Last House on the Left | - | - | - | $164,253 | 32 | $237,016 | May 15 | Universal Pictures International (UPI) | false |
| 20 | The First Day of the Rest of Your Life | - | - | - | $140,717 | 15 | $267,978 | May 8 | Polyfilm Verleih | false |
| 21 | Knowing | - | - | - | $111,265 | 39 | $609,380 | Apr 10 | Constantin Film | false |
| 22 | Princess Lillifee | - | - | - | $105,093 | 51 | $601,630 | Mar 27 | Constantin Film | false |
| 23 | Contact High | - | - | - | $96,826 | 28 | $246,454 | Apr 17 | - | false |
| 24 | The Reader | - | - | - | $89,488 | 46 | $1,294,334 | Feb 27 | Senator Film | false |
| 25 | Mid-August Lunch | - | - | - | $88,687 | 15 | $172,409 | May 15 | Filmladen | false |
| 26 | The Duchess | - | - | - | $86,805 | 13 | $156,158 | Apr 24 | Filmladen | false |
| 27 | The Boat That Rocked | - | - | - | $72,576 | 55 | $270,808 | Apr 17 | Universal Pictures International (UPI) | false |
| 28 | Rachel Getting Married | - | - | - | $67,022 | 17 | $154,559 | May 22 | Sony Pictures Releasing | false |
| 29 | I Saw the Sun 2009 Re-release | - | - | - | $60,339 | 9 | $180,106 | Apr 17 | - | false |
| 30 | Lilly the Witch: The Dragon and the Magic Book | - | - | - | $57,343 | 85 | $1,515,407 | Feb 20 | Walt Disney Pictures | false |
| 31 | Welcome to the Sticks | - | - | - | $53,884 | 39 | $1,354,881 | Nov 14 | Luna Filmverleih | false |
| 32 | Gran Torino | - | - | - | $36,016 | 27 | $467,728 | Mar 6 | Warner Bros. | false |
| 33 | Let the Right One In | - | - | - | $35,721 | 13 | $40,570 | May 1 | Filmladen | false |
| 34 | The Three Investigators and the Secret of Terror Castle | - | - | - | $30,276 | 56 | $313,879 | Mar 20 | Walt Disney Pictures | false |
| 35 | Sturmfrei | - | - | - | $24,973 | 28 | $60,560 | Apr 24 | Einhorn-Film | false |
| 36 | A Secret | - | - | - | $23,785 | 7 | $62,611 | Apr 10 | Polyfilm Verleih | false |
| 37 | The Limits of Control | - | - | - | $22,250 | 6 | $84,749 | May 29 | Constantin Film | false |
| 38 | The Forbidden Kingdom | - | - | - | $20,803 | 20 | $50,908 | May 29 | - | false |
| 39 | Race to Witch Mountain | - | - | - | $18,243 | 56 | $144,130 | Apr 9 | Walt Disney Pictures | false |
| 40 | Berlin Calling | - | - | - | $17,825 | 7 | $21,057 | May 1 | Polyfilm Verleih | false |
| 41 | Universalove | - | - | - | $12,852 | 3 | $54,026 | Apr 17 | Stadtkino Filmverleih | false |
| 42 | The Crocodiles | - | - | - | $11,607 | 40 | $176,717 | Mar 27 | Constantin Film | false |
| 43 | For My Father | - | - | - | $10,228 | 5 | $12,300 | May 8 | Filmladen | false |
| 44 | Palermo Shooting | - | - | - | $10,171 | 6 | $15,499 | Apr 24 | - | false |
| 45 | Wendy and Lucy | - | - | - | $8,304 | 1 | $21,867 | May 8 | Stadtkino Filmverleih | false |
| 46 | Gangster Girls | - | - | - | $6,786 | 4 | $32,025 | Mar 27 | Stadtkino Filmverleih | false |
| 47 | The Tale of Despereaux | - | - | - | $6,644 | 48 | $289,342 | Mar 20 | Universal Pictures International (UPI) | false |
| 48 | John Rabe | - | - | - | $3,041 | 11 | $19,025 | Apr 10 | Filmladen | false |
| 49 | 7915 Km | - | - | - | $2,499 | 4 | $34,911 | Mar 6 | Stadtkino Filmverleih | false |
| 50 | The Pink Panther 2 | - | - | - | $2,492 | 80 | $448,932 | Mar 13 | Sony Pictures Releasing | false |
| 51 | Confessions of a Shopaholic | - | - | - | $2,017 | 56 | $657,984 | Mar 12 | Walt Disney Pictures | false |
| 52 | Frontier of the Dawn | - | - | - | $1,702 | 1 | $10,421 | May 29 | Stadtkino Filmverleih | false |
| 53 | Lorna's Silence | - | - | - | $1,639 | 6 | $19,953 | Apr 3 | Filmladen | false |
| 54 | Pain of Autumn | - | - | - | $1,123 | 3 | $1,123 | May 1 | - | false |
| 55 | Religulous | - | - | - | $1,058 | 1 | $11,856 | Apr 3 | Senator Film | false |
| 56 | Hilde | - | - | - | $986 | 11 | $86,371 | Mar 13 | Warner Bros. | false |
| 57 | Fay Grim | - | - | - | $512 | 1 | $5,638 | May 22 | - | false |
| 58 | Underworld: Rise of the Lycans | - | - | - | $248 | 52 | $524,711 | Feb 27 | Sony Pictures Releasing | false |
| 59 | The Plane 2009 Re-release | - | - | - | $92 | 2 | $92 | May 1 | Einhorn-Film | false |
