Domestic Box Office For May 2008
| Rank | Release | Gross | Max Th | Opening | % of Total | Open Th | Open | Close | Distributor |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Iron Man | $318,604,126 | 4,154 | $98,618,668 | 31% | 4,105 | May 2 | Oct 2 | Paramount Pictures |
| 2 | Indiana Jones and the Kingdom of the Crystal Skull | $317,101,119 | 4,264 | $100,137,835 | 31.6% | 4,260 | May 22 | Oct 16 | Paramount Pictures |
| 3 | Sex and the City | $152,647,258 | 3,325 | $57,038,404 | 37.4% | 3,285 | May 30 | Sep 18 | Warner Bros. |
| 4 | The Chronicles of Narnia: Prince Caspian | $141,621,490 | 3,929 | $55,034,805 | 38.9% | 3,929 | May 16 | Sep 4 | Walt Disney Studios Motion Pictures |
| 5 | What Happens in Vegas | $80,277,646 | 3,255 | $20,172,474 | 25.1% | 3,215 | May 9 | Sep 18 | Twentieth Century Fox |
| 6 | The Strangers | $52,597,610 | 2,477 | $20,997,985 | 39.9% | 2,466 | May 30 | Jul 24 | Rogue Pictures |
| 7 | Made of Honor | $46,012,734 | 2,816 | $14,756,850 | 32.1% | 2,729 | May 2 | Jun 29 | Sony Pictures Releasing |
| 8 | Speed Racer | $43,945,766 | 3,606 | $18,561,337 | 42.2% | 3,606 | May 9 | Aug 7 | Warner Bros. |
| 9 | Redbelt | $2,345,941 | 1,379 | $63,361 | 2.7% | 6 | May 2 | Jul 17 | Sony Pictures Classics |
| 10 | The Fall | $2,266,905 | 111 | $79,611 | 3.5% | 9 | May 9 | Jan 7 | Roadside Attractions |
| 11 | Son of Rambow | $1,785,505 | 155 | $53,789 | 3% | 5 | May 2 | Aug 14 | Paramount Vantage |
| 12 | The Children of Huang Shi | $1,031,872 | 43 | $42,755 | 4.1% | 7 | May 23 | Oct 16 | Sony Pictures Classics |
| 13 | Before the Rains | $1,029,655 | 44 | $48,159 | 4.7% | 8 | May 9 | Sep 18 | Roadside Attractions |
| 14 | The Edge of Heaven | $742,349 | 20 | $14,257 | 1.9% | 1 | May 21 | Oct 16 | Strand Releasing |
| 15 | Fugitive Pieces | $635,783 | 38 | $102,212 | 16.1% | 30 | May 2 | Aug 14 | The Samuel Goldwyn Company |
| 16 | War, Inc. | $580,862 | 33 | $35,336 | 6.1% | 2 | May 23 | Aug 7 | First Look International |
| 17 | Reprise | $554,826 | 15 | $49,060 | 8.8% | 3 | May 16 | Jul 24 | Miramax |
| 18 | Bhoothnath | $476,032 | 64 | $330,246 | 69.4% | 64 | May 9 | May 22 | Eros Worldwide |
| 19 | Savage Grace | $435,746 | 22 | $22,311 | 5.1% | 2 | May 28 | Aug 21 | IFC Films |
| 20 | Bigger Stronger Faster* | $308,575 | 26 | $31,576 | 10.2% | 6 | May 30 | Aug 21 | Magnolia Pictures |
| 21 | OSS 117: Cairo, Nest of Spies | $303,543 | 13 | $31,418 | 10.4% | 9 | May 9 | Oct 23 | Music Box Films |
| 22 | Surfwise | $269,994 | 13 | $10,304 | 3.8% | 1 | May 9 | Aug 7 | Magnolia Pictures |
| 23 | The Foot Fist Way | $234,286 | 25 | $36,391 | 15.5% | 4 | May 30 | Aug 14 | Paramount Vantage |
| 24 | How the Garcia Girls Spent Their Summer | $215,303 | 84 | $91,432 | 42.5% | 84 | May 18 | - | Maya Entertainment |
| 25 | My Father My Lord | $203,708 | 9 | $24,096 | 11.8% | 6 | May 16 | Nov 27 | Kino International |
| 26 | Mister Lonely | $167,396 | 8 | $16,769 | 10% | 1 | May 2 | Aug 7 | IFC Films |
| 27 | The Unknown Woman | $152,114 | 2 | $5,701 | 3.7% | 1 | May 30 | - | Outsider Pictures |
| 28 | A Jihad for Love | $105,651 | 5 | $10,519 | 10% | 1 | May 21 | Sep 25 | First Run |
| 29 | Il trittico dell'amore | $80,374 | 43 | $2,235 | 2.8% | 2 | May 2 | Oct 23 | Emerging Pictures |
| 30 | America the Beautiful | $76,173 | 5 | $6,760 | 8.9% | 1 | May 9 | Nov 23 | First Independent Pictures |
| 31 | Stuck | $67,505 | 16 | $8,844 | 13.1% | 2 | May 30 | Jul 17 | THINKFilm |
| 32 | Bloodline | $64,698 | 5 | $6,658 | 10.3% | 1 | May 9 | Aug 28 | Cinema Libre Studio |
| 33 | Love and Honor | $60,910 | 3 | $5,234 | 8.6% | 2 | May 2 | Nov 6 | Eleven Arts |
| 34 | Blood of My Blood | $55,730 | 7 | $8,385 | 15% | 1 | May 14 | Jul 17 | IFC Films |
| 35 | La Rondine | $49,088 | 5 | $2,972 | 6.1% | 1 | May 19 | Sep 18 | Emerging Pictures |
| 36 | XXY | $48,334 | 2 | $3,241 | 6.7% | 1 | May 2 | Nov 20 | Film Movement |
| 37 | The Babysitters | $44,852 | 22 | $23,518 | 52.4% | 22 | May 9 | May 22 | Peace Arch Entertainment Group |
| 38 | The Tracey Fragments | $32,645 | 4 | $3,002 | 9.2% | 1 | May 9 | May 22 | THINKFilm |
| 39 | Yella | $30,647 | 2 | $7,767 | 25.3% | 2 | May 16 | Dec 11 | The Cinema Guild |
| 40 | Vivre sa vie | $24,517 | 1 | $8,336 | 34% | 1 | May 30 | Jul 24 | Janus Films |
| 41 | Trying to Get Good: The Jazz Odyssey of Jack Sheldon | $19,712 | 1 | $4,792 | 24.3% | 1 | May 30 | Jun 15 | Reel Source |
| 42 | Noise | $16,513 | 2 | $3,687 | 22.3% | 2 | May 9 | Jun 5 | THINKFilm |
| 43 | Poultrygeist: Night of the Chicken Dead | $13,804 | 1 | $10,624 | 77% | 1 | May 9 | May 18 | Troma |
| 44 | Battle for Haditha | $10,310 | 2 | $1,982 | 19.2% | 1 | May 7 | May 22 | Lafayette Films |
| 45 | As It Is in Heaven 2008 Re-release | $10,236 | 1 | $2,402 | 23.5% | 1 | May 2 | - | Vitagraph Films |
| 46 | As Tears Go By | $9,436 | 1 | $4,279 | 45.3% | 1 | May 2 | May 15 | Kino International |
| 47 | Turn the River | $5,149 | 2 | $2,722 | 52.9% | 1 | May 9 | May 18 | Screen Media Films |
| 48 | Twisted: A Balloonamentary | $4,218 | 2 | $2,354 | 55.8% | 1 | May 23 | Jun 1 | - |
| 49 | Heavy Metal in Baghdad | $4,070 | 2 | $2,012 | 49.4% | 2 | May 23 | May 29 | Hart Sharp Entertainment |
| 50 | House of Usher | $1,677 | 2 | $891 | 53.1% | 1 | May 9 | Jun 19 | Regent Releasing |
| 51 | Kiss Me Deadly | $1,085 | 2 | $214 | 19.7% | 1 | May 2 | Jun 19 | Regent Releasing |
